Spine Radiosurgery, Second Edition , is a comprehensive text that includes discussions of the latest devices, treatment planning techniques, target definition, and patient selection in this specialty. Written by leading experts in the fields of neurosurgery, radiation oncology, and medical physics, this book is the definitive reference for clinical applications of state-of-the-art radiosurgery of the spine. Key Features: Six new chapters on such topics as histopathological examination of spinal lesions, minimally invasive techniques, and treatment of spinal chordomas More than 100 full-color illustrations demonstrate key concepts Discussion of new treatments for metastatic spine disease and spinal cord compression This book is a must-have resource for clinicians, fellows, and residents in neurosurgery and radiation oncology. Spine surgeons, orthopaedists, medical physicists, and oncologists at all levels will also benefit from the wealth of information provided.

Written by leading experts from the fields of neurosurgery, radiation oncology, and medical physics, this book is the definitive reference for clinical applications of state-of-the-art radiosurgery of the spine. It discusses the benefits as well as the limitations of current spine radiosurgery treatments for benign and malignant spine disorders, primary and metastatic tumors, and spinal cord arteriovenous malformations. The opening chapters present the essential background information on relevant spinal cord radiobiology, physics, and technology, followed by chapters on specific applications of spine radiosurgery covering indications, techniques, outcomes, and possible complications. Highlights: Practical guidelines on radiosurgery target delineation, dose selection and escalation, patient immobilization, and quality assurance Comprehensive discussion of the design of various radiosurgical devices and the technical approaches recommended for the use of each More than 100 illustrations, most in full-color, to demonstrate key concepts This is a must-have resource for clinicians, medical physicists, fellows, and residents in neurosurgery and radiation oncology. Spine surgeons, orthopaedists, and oncologists at all levels of expertise will also benefit from the wealth of information provided in this book.

Following recent developments in hypofractionated stereotactic radiation therapy (SRT) for brain and spine tumors, this new edition offers a fully updated and comprehensive "how-to" guidance on hypofractionated SRT for brain and spine metastases, glioma, benign tumors, and other tumor types. Presenting the state of the art of the technology and practice, this book: • Discusses the pros and cons of hypofractionated SRT compared to single-fraction radiosurgery, providing a deeper understanding of radiosurgery and radiobiology • Explains the toxicity and adverse effects of hypofractionated SRT including the dosage of 24 Gy in two spine SBRT fractionation schemes, aiding practitioners in communicating the risks and benefits of treatment and in obtaining consent from their patients • Outlines the current standards for safe practice, including checklists for implementation • Explores new technologies for brain and spine tumors including LITT, MR-guided focused ultrasound, and Zap technology, with chapters authored by well-recognized experts in the radiation, oncology, and neurosurgery communities; this book delivers a level of technological and clinical detail not available in journal papers This book is suitable for radiation oncologists, neurosurgeons, and medical physicists who specialize in brain and/or spine radiosurgery or want to start a program and need a comprehensive reference with key checklists for practice.

Handbook of Radiosurgery in CNS Disease is a concise and practical manual offering radiation oncology, neurology, and neurosurgery residents, trainees, fellows, and clinicians up-to-date information on the role of radiosurgery within the overall context of CNS disease management. The emphasis is on decision making and the evaluation of radiosurgery as a viable option among the suite of potentially applicable treatments, including frame-based systems, non-invasive body immobilization, and image-guided targeting. The book examines radiosurgery as a treatment modality for various CNS pathologies, discussing relevant radiobiology, current technology, and the technical aspects of specific procedures. Chapters organized by pathology provide practical coverage of clinical evaluations, patient selection and management decision-making, and relevant points in radiosurgical applications for the entity under discussion. Pertinent cases are presented to demonstrate the process for each treatment paradigm. A unique collaboration of editors with an international reputation for excellence in radiation oncology, vascular neurosurgery, and neurosurgical oncology will offer insights into the role of radiosurgery in the entire central nervous system (i.e. both brain and spine). Handbook of Radiosurgery in CNS Disease features: Practical focus on key clinical issues in radiosurgery of CNS disease: patient selection, radiosurgery in context with other modalities, pitfalls Coverage of cranial and extracranial disease Relevant cases illustrate discussion of each treatment paradigm Outstanding editorial team Concise format makes for an easy review or quick reference, in contrast to large texts

Controversies in Stereotactic Radiosurgery: Best Evidence Recommendations is a comprehensive reference that compiles, synthesizes, and summarizes the most relevant scientific literature on the topic. Each succinct, problem-oriented chapter addresses a different controversy surrounding stereotactic radiosurgery. This book saves physicians significant amounts of time by distilling years of scientific research into sound guidelines that will help them make fully-informed treatment decisions. Key Features: Covers both intracranial and spine radiosurgery, providing complete coverage of this rapidly evolving technology Includes more than 35 chapters on treatment controversies for brain and spine tumors as well as vascular malformations Contains summary tables throughout the text that present the main conclusions of published studies All neurosurgeons, radiation oncologists, and neuro-oncologists, involved in the treatment of patients who may be candidates for stereotactic radiosurgery of the brain and spine will find this book to be an essential decision making guide.

This book is a comprehensive review of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT): its physics, clinical evidence, indications, and future directions. The utilization of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) is increasing internationally because of several factors. First, it offers patients a local treatment option that has demonstrated effectiveness similar to traditional surgery without the morbidity of general anesthesia and open surgical resection. Second, recent advancements in the quality of scientific evidence supporting a SRS or SBRT-containing approach in patients continues to evolve and demonstrate favorable disease-specific outcomes with little, if any, toxicity in various anatomic disease sites and for various conditions including cancer, benign tumors, and other psychiatric and neurologic conditions. Third, and most provocatively, is the notion that definitive local therapy (i.e. SRS or SBRT) in patients with cancer can boost the immune system to fight cancer in other sites throughout the body. While traditional medical knowledge would suggest that all patients with metastatic cancer are incurable, there is a mounting body of evidence that there is a subset of these patients that can be cured with definitive SRS or SBRT. This volume thus delves into each of these benefits and aspects of treatment, guiding physicians to the best treatment plan for their patients. Expert, international authors provide guidelines for SRS and SBRT use by clinicians. Chapters are divided into six main sections: Radiobiology of Radiosurgery and Stereotactic Body Radiation Therapy, Intracranial Radiosurgery Technique, Intracranial Radiosurgery by Indication, Stereotactic Body Radiation Therapy Technique, Stereotactic Body Radiation Therapy by Indication, The Future of Radiosurgery and SBRT. Overall physics are explained, as well as specific considerations for particular surgical tools (including the Leksell Gamma Knife and Accuray CyberKnife), techniques (including fractionated and charged particle radiosurgery), and anatomic sites (including brain metastases, pituitary tumors, and the prostate). Detailed images and charts enhance the chapters. This book provides physicians with a single, practical resource incorporating both of these broad categories of treatment, SRS and SBRT, and better defines the current role and the direction of radiosurgery.

This book provides the reader with a detailed update on the use of stereotactic radiosurgery (SRS) in patients with lesions of the brain and other parts of the body. The aim is not simply to explain the application of SRS and document its value with reference to the author's own clinical experiences and other published evidence, but also to contextualize the technology within a new strategic concept of cancer care. When embedded within an appropriate conceptual framework, technology becomes pivotal in changing therapeutic strategies. A new paradigm that is increasingly impacting on clinical practice is the oligometastatic state, on the basis that long-term survival might be achieved in patients with a low volume and number of metastatic lesions. This book accordingly addresses the value of SRS in patients with oligometastases of solid tumors to the brain, lung, spine, and liver. In addition, it examines the use of SRS in patients with diverse brain lesions, early-stage stage lung cancer, liver cancer, and early-stage prostate cancer. Readers will be persuaded that SRS, using cutting-edge imaging technologies to deliver precisely targeted radiation therapy, represents an exciting non-invasive procedure that holds great promise for the present and the future of cancer care.