Fully rewritten and updated for the cutting-edge sixth edition, Spencer's Pathology of the Lung follows in its predecessors' footsteps as the gold-standard textbook of pulmonary diseases. All recognized diseases of the lungs are discussed and illustrated with extensive, high-quality color images. Each chapter includes practical, clear and concise diagnostic features, including immunohistochemistry, molecular tests and differential diagnoses, while rare entities are discussed and illustrated in detail. This thoroughly reworked edition includes new classification schemes and the latest understanding of the pathophysiology and molecular aspects of a wide range of diseases. Non-neoplastic diseases are presented according to epidemiology, genetics, clinical manifestations, radiographic findings, pathology, cytology, laboratory findings, pathogenesis, differential diagnosis, prognosis and natural history. Neoplasms are discussed according to cell or origin with sections devoted to genetics, molecular findings and clinicopathologic correlations. Downloadable versions of all images are available on a CD-ROM packaged with the print book. Written and edited by leading experts in the field, this is an essential resource for practising and trainee pathologists.

This book comprehensively covers aortic dissection and acute aortic syndromes. Topics covered include the pathology, genetics, diagnosis, medical treatment and surgical management of uncomplicated and complicated aortic dissection, including endovascular stenting. In addition, imaging and follow-up procedures after initial surgical treatment are reviewed along with acute and chronic type A and type B dissection. Potential complications that can be encountered at various treatment stages and management strategies are also detailed. Aortic Dissection and Acute Aortic Syndromes comprehensively reviews aortic dissection in an easy to read, illustration-rich book. It is therefore an essential resource for both trainee and experienced cardiologist, cardiac surgeon and any other medical professionals involved in the management of these patients.

Emergency bedside ultrasound assessment is well established for adult patients, but has only recently been introduced into everyday clinical practice for the care of pediatric patients. Pediatric Emergency Critical Care and Ultrasound is a concise, practical text which explains the principles of ultrasound, its diagnostic application in all organ systems and its use as a procedural adjunct. Both well-established and innovative applications are described, assisting the practitioner in incorporating ultrasound into daily practice, facilitating patient care and decreasing radiation exposure. Case studies and abundant illustrations enable the reader to study the appropriate techniques in detail and learn from real examples from the pediatric emergency department and intensive care unit. Pediatric Emergency Critical Care and Ultrasound is the first comprehensive bedside ultrasonography resource focusing on pediatric patients and is essential reading not only for pediatric emergency medicine subspecialists but for all emergency physicians, intensivists/critical care physicians and pediatricians.

This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow’s generation of life-saving cardiac devices.

Equal parts true crime, twentieth-century history, and science thriller, The Poisoner's Handbook is "a vicious, page-turning story that reads more like Raymond Chandler than Madame Curie." —The New York Observer “The Poisoner’s Handbook breathes deadly life into the Roaring Twenties.” —Financial Times “Reads like science fiction, complete with suspense, mystery and foolhardy guys in lab coats tipping test tubes of mysterious chemicals into their own mouths.” —NPR: What We're Reading A fascinating Jazz Age tale of chemistry and detection, poison and murder, The Poisoner's Handbook is a page-turning account of a forgotten era. In early twentieth-century New York, poisons offered an easy path to the perfect crime. Science had no place in the Tammany Hall-controlled coroner's office, and corruption ran rampant. However, with the appointment of chief medical examiner Charles Norris in 1918, the poison game changed forever. Together with toxicologist Alexander Gettler, the duo set the justice system on fire with their trailblazing scientific detective work, triumphing over seemingly unbeatable odds to become the pioneers of forensic chemistry and the gatekeepers of justice. In 2014, PBS's AMERICAN EXPERIENCE released a film based on The Poisoner's Handbook.

While the global economy languishes, one place just keeps growing despite failing banks, uncertain markets, and high unemployment: Silicon Valley. In the last two years, more than 100 incubators have popped up there, and the number of angel investors has skyrocketed. Today, 40 percent of all venture capital investments in the United States come from Silicon Valley firms, compared to 10 percent from New York. In Secrets of Silicon Valley, entrepreneur and media commentator Deborah Perry Piscione takes us inside this vibrant ecosystem where meritocracy rules the day. She explores Silicon Valley's exceptionally risk-tolerant culture, and why it thrives despite the many laws that make California one of the worst states in the union for business. Drawing on interviews with investors, entrepreneurs, and community leaders, as well as a host of case studies from Google to Paypal, Piscione argues that Silicon Valley's unique culture is the best hope for the future of American prosperity and the global business community and offers lessons from the Valley to inspire reform in other communities and industries, from Washington, DC to Wall Street.