This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Tanya Huff’s supernatural fantasy Smoke series, with a gothic twist • Mix of ghostly mystery, paranormal horror, and dark humor • Lamba Award nominated Fans of the X-Files and Twin Peaks will love acclaimed master of contemporary fantasy Tanya Huff’s twisted version of vampires, wizards, and TV terror. Tony Foster, fledgling wizard and now trainee assistant director on Darkest Night—the syndicated vampire detective show—is hoping that they only supernatural events he’ll be caught up in are those in the script. But that isn’t meant to be, for a demonic convergence is about to begin, creating weak spots through which lesser demons may enter the world. To complicate matters, Leah, the incredibly seductive stuntwoman who freelances for the show, is an immortal Demongate. Should Leah die, the Demongate will open and her sensual demon master will wreak havoc upon the unsuspecting human race. Can Tony—with the help of Leah, Henry, a tabloid reporter, a Mountie, and the cast of Darkest Night—halt a demonic invasion and stave off the end of the world?

Drinkina rye and water with Grandma. Guns in False Creek. Frat boy homies from the North Delta ghetto. Samuel L. Jackson. Phantom Lord & Metallica. A kid whoa s got the hots for his moma Hunh? Thata s right. Ita s all here in this collection of immediate, lean and visceral short fiction from Clint Burnham."

In this “incredible read on some incredible days and nights in the old association” (Adrian Wojnarowski, ESPN senior NBA insider) Charles Oakley—one of the toughest and most loyal players in NBA history—tells his unfiltered stories about his basketball journey and his relationships with Michael Jordan, LeBron James, Charles Barkley, Patrick Ewing, Phil Jackson, Pat Riley, James Dolan, Donald Trump, George Floyd, and many others. If you ask a New York Knicks fan about Charles Oakley, you better prepare to hear the love and a favorite story or two. But his individual stats weren’t remarkable, and while he helped power the Knicks to ten consecutive playoffs, he never won a championship. So why does he hold such a special place in the minds, hearts, and memories of NBA players and fans? Because over the course of nineteen years in the league, Oakley was at the center of more unbelievable encounters than Forrest Gump, and nearly as many fights as Mike Tyson. He was the friend you wish you had, and the enemy you wish you’d never made. If any opposing player was crazy enough to start a fight with him, or God forbid one of his teammates, Oakley would end it. “I can’t remember every rebound I grabbed but I do have a story—the true story—of just about every punch and slap on my resume,” he says. In The Last Enforcer, Oakley shares one incredible story after the next—all in his signature “unflinchingly tough, honest, and ultimately endearing” (Harvey Araton, New York Times bestselling author) style—about his life in the paint and beyond, fighting for rebounds and respect. You’ll look back on the era of the 1990s NBA, when tough guys with rugged attitudes, unflinching loyalty, and hard-nosed work ethics were just as important as three-point sharpshooters. You’ll feel like you were on the court, in the room, can’t believe what you just saw, and need to tell everyone you know about it.

"With potent, lyrical language and a profound knowledge of storytelling, Shaw encourages and illuminates the mythic in our own lives. He is a modern-day bard." – Madeline Miller, author of Circe and The Song of Achilles At a time when we are all confronted by not one, but many crossroads in our modern lives—identity, technology, trust, politics, and a global pandemic—celebrated mythologist and wilderness guide Martin Shaw delivers Smoke Hole: three metaphors to help us understand our world, one that is assailed by the seductive promises of social media and shadowed by a health crisis that has brought loneliness and isolation to an all-time high. Smoke Hole is a passionate call to arms and an invitation to use these stories to face the complexities of contemporary life, from fake news, parenthood, climate crises, addictive technology and more. Shaw urges us to reclaim our imagination and untangle ourselves from modern menace, letting these tales be our guide. More Praise: "I can still remember the first time I heard Martin Shaw tell a story. The tale that emerged was like a living thing, bounding around, throwing itself at us there listening. I had never heard anything like it before." – Paul Kingsnorth, Booker shortlisted author of The Wake "Martin Shaw’s work is so very beautiful. A new animal. His love of images is deep and contagious." – Coleman Barks, author of The Essential Rumi "Through feral tales and poetic exegesis, Martin Shaw makes you re-see the world, as a place of adventure, and of initiation, as perfect home, and as perfectly other. What a gift." – David Keenan, author of Xstabeth "Shaw has so much wisdom and knowledge about the old stories, it emanates from his pores." – John Densmore, The Doors

Data suggest that exposure to secondhand smoke can result in heart disease in nonsmoking adults. Recently, progress has been made in reducing involuntary exposure to secondhand smoke through legislation banning smoking in workplaces, restaurants, and other public places. The effect of legislation to ban smoking and its effects on the cardiovascular health of nonsmoking adults, however, remains a question. Secondhand Smoke Exposure and Cardiovascular Effects reviews available scientific literature to assess the relationship between secondhand smoke exposure and acute coronary events. The authors, experts in secondhand smoke exposure and toxicology, clinical cardiology, epidemiology, and statistics, find that there is about a 25 to 30 percent increase in the risk of coronary heart disease from exposure to secondhand smoke. Their findings agree with the 2006 Surgeon General's Report conclusion that there are increased risks of coronary heart disease morbidity and mortality among men and women exposed to secondhand smoke. However, the authors note that the evidence for determining the magnitude of the relationship between chronic secondhand smoke exposure and coronary heart disease is not very strong. Public health professionals will rely upon Secondhand Smoke Exposure and Cardiovascular Effects for its survey of critical epidemiological studies on the effects of smoking bans and evidence of links between secondhand smoke exposure and cardiovascular events, as well as its findings and recommendations.

Isaiah Quintabe—an unlicensed detective for all seasons—and his best friend and masterful sidekick, Juanell Dodson, are at a crossroads in this latest installment of the "aggressively entertaining" IQ series (New York Times). This time, their lives may never be the same. Isaiah Quintabe is no longer IQ, the genius of East Long Beach; instead, he’s a man on the road and on the run, hiding in a small Northern California town when his room is broken into by a desperate young man on the trail of the state’s most prolific serial killer. His old partner, Juanell Dodson, must go straight or lose his wife and child. His devil’s bargain? An internship at an LA advertising agency, where it turns out the rules of the street have simply been dressed in business casual, but where the aging company’s fortunes may well rest on their ability to attract a younger demographic. Dodson—”the hustler’s hustler”—just may be the right man for the job. Ide is the crime writer’s crime writer, and he’s filled his best novel yet with desperate souls, courageous outcasts, an ex-stripper who’ll do anything to protect her son, and wild half-brothers who may be the very incarnation of evil. With deft plotting, lacerating humor, and a keen eye for the ways in which characters rise or fall based on their ties to one another, Smoke is Joe Ide’s crowning achievement.