Smith & Sloan Family Data
Title | Smith & Sloan Family Data PDF eBook |
Author | Hugh C. Smith |
Publisher | |
Pages | |
Release | 1965* |
Genre | |
ISBN |
Sloan, Hale and Smith Family History 1996
Title | Sloan, Hale and Smith Family History 1996 PDF eBook |
Author | Jean Fitsch Justice (Olive Paschal Keener, Betty Smith Landon Kroeger and Lou Smith Olson) |
Publisher | |
Pages | |
Release | 1996 |
Genre | Family History |
ISBN |
Sloan, Hale and Smith Family History
Title | Sloan, Hale and Smith Family History PDF eBook |
Author | Jean Fitch Justice |
Publisher | |
Pages | 376 |
Release | 1996 |
Genre | |
ISBN |
James Sloan (1769-1853) was born in Rockbridge County, Virginia and served in the American Revolution. He eventually settled in Kentucky. He was the father of eleven children. Descendants married into the Hale family. One of the earliest known ancestors of the Hale family was Lewis Hale (1746-1802) who married Mary Burwell and settled in Grayson County, Virginia. His descendants moved to Kentucky. Descendants live in Kentucky, Missouri, Texas, Nebraska, Colorado and other parts of the United States.
National Data Book
Title | National Data Book PDF eBook |
Author | |
Publisher | |
Pages | 196 |
Release | 1987 |
Genre | Endowments |
ISBN |
Genealogy of the Corbett Family
Title | Genealogy of the Corbett Family PDF eBook |
Author | E. Clark Corbett |
Publisher | |
Pages | 96 |
Release | 1917 |
Genre | |
ISBN |
Novel Approaches to the Analysis of Family Data in Genetic Epidemiology
Title | Novel Approaches to the Analysis of Family Data in Genetic Epidemiology PDF eBook |
Author | Xiangqing Sun |
Publisher | Frontiers Media SA |
Pages | 86 |
Release | 2016-08-17 |
Genre | Genetics |
ISBN | 2889199320 |
Genome-wide association studies (GWAS) for complex disorders with large case-control populations have been performed on hundreds of traits in more than 1200 published studies (http://www.genome.gov/gwastudies/) but the variants detected by GWAS account for little of the heritability of these traits, leading to an increasing interest in using family based designs. While GWAS studies are designed to find common variants with low to moderate attributable risks, family based studies are expected to find rare variants with high attributable risk. Because family-based designs can better control both genetic and environmental background, this study design is robust to heterogeneity and population stratification. Moreover, in family-based analysis, the background genetic variation can be modeled to control the residual variance which could increase the power to identify disease associated rare variants. Analysis of families can also help us gain knowledge about disease transmission and inheritance patterns. Although a family-based design has the advantage of being robust to false positives, novel and powerful methods to analyze families in genetic epidemiology continue to be needed, especially for the interaction between genetic and environmental factors associated with disease. Moreover, with the rapid development of sequencing technology, advances in approaches to the design and analysis of sequencing data in families are also greatly needed. The 11 articles in this book all introduce new methodology and, using family data, substantial new findings are presented in the areas of infectious diseases, diabetes, eye traits, autism spectrum disorder and prostate cancer.
The Handbook of American Genealogy
Title | The Handbook of American Genealogy PDF eBook |
Author | |
Publisher | |
Pages | 400 |
Release | 1943 |
Genre | Genealogists |
ISBN |