Focusing exclusively on SPARC hardware and UNIX, this tutorial/reference on Sun Performance Tuning contains hard recommendations and expert opinions that are often needed, but not found in other books on the subject. Includes an appendix on a measurement methodology that describes a way of analyzing and modelling the performance of multiuser systems using sophisticated tools.

Fragment-based drug discovery is a rapidly evolving area of research, which has recently seen new applications in areas such as epigenetics, GPCRs and the identification of novel allosteric binding pockets. The first fragment-derived drug was recently approved for the treatment of melanoma. It is hoped that this approval is just the beginning of the many drugs yet to be discovered using this fascinating technique. This book is written from a Chemist's perspective and comprehensively assesses the impact of fragment-based drug discovery on a wide variety of areas of medicinal chemistry. It will prove to be an invaluable resource for medicinal chemists working in academia and industry, as well as anyone interested in novel drug discovery techniques.

This volume details protocols on formulation, surface modification, characterization, and application of a variety of pharmaceutical nanocarriers such as micelles, nanoparticles, dendrimers, carbon dots, polymersomes, and others. Chapters are targeted toward investigators working in academic and industrial laboratories conducting research in the broad field of pharmaceutical sciences, with an emphasis on drug delivery. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Pharmaceutical Nanotechnology: Basic Protocols aims to be a source of inspiration to all investigators who are interested in the potential of the merger of nanotechnology with pharmaceutical sciences.

This book is about the UN's role in housing, land, and property rights in countries after violent conflict.

This book discusses the significance, relevance, and usefulness of professional ethics in the context of higher education. It highlights the pivotal role of professional ethics in offering teachers a better understanding of their responsibilities, duties, rights, and institutional obligations as they work to provide quality education. The volume investigates the connection between the adoption of professional ethics by individual faculty members in higher education and the development of work cultures in higher educational institutions. It explores the requisite modifications of the Teachers’ Code of Ethics in relation to the usage of Information and Communication Technologies (ICTs) in teaching–learning platforms. While examining the validity, reliability, and application of professional ethics in the higher education sector, the book also illustrates the application of codes of ethics to resolve conflicting interests and commitments. This book will be useful to scholars and researchers in higher education, the philosophy of education, applied ethics, public policy, and the social sciences.

The book is a compendium of the aforementioned subclass of models of Basal Ganglia, which presents some the key existent theories of Basal Ganglia function. The book presents computational models of basal ganglia-related disorders, including Parkinson’s disease, schizophrenia, and addiction. Importantly, it highlights the applications of understanding the role of the basal ganglia to treat neurological and psychiatric disorders. The purpose of the present book is to amend and expand on James Houk’s book (MIT press; ASIN: B010BF4U9K) by providing a comprehensive overview on computational models of the basal ganglia. This book caters to researchers and academics from the area of computational cognitive neuroscience.