This work contains updated and clinically relevant information about tuberculosis. It is aimed at providing a succinct overview of history and disease epidemiology, clinical presentation and the most recent scientific developments in the field of tuberculosis research, with an emphasis on diagnosis and treatment. It may serve as a practical resource for students, clinicians and researchers who work in the field of infectious diseases.

Published as two individual books in its previous editions, this acclaimed reference now comes to you as one comprehensive two-volume resource, covering the entire range of esophageal and thoracic surgery for adults and children. Sixty nine brand-new chapters and 92 new authors deliver state-of-the-art, clear how-to-do-it guidance on the latest surgical techniques for the treatment of lung infections, lung cancer, benign conditions, trauma, reflux, and more-so you can effectively manage every common and uncommon condition you encounter. A new full-color design presents outstanding visual guidance that shows you exactly how to proceed, and a logical organization throughout makes reference easy. As an Expert Consult title, this thoroughly updated 3rd edition comes with access to the complete contents online, fully searchable-enabling you to consult it rapidly from any computer with an Internet connection. Addresses all surgical diseases of the chest wall, chest cavity, upper airway, lungs, pleura, and diaphragm in adults and children, giving you the comprehensive coverage you need for the patients you see. Presents clinical commentary at the end of each chapter that offers you a variety of viewpoints regarding the pros, cons, and complications associated with the techniques used to treat a patient.

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis and still represents one of the global health threats to mankind. The World Health Organization estimated more than 10 million new cases and reported more than 1.5 million deaths in 2019, thus ranking TB among the main causes of death due to a single pathogen. Standard anti-TB therapy includes four first-line antibiotics that should be administered for at least six months. However, in the case of multi- and extensively drug-resistant TB, second-line medications must be used and these frequently cause severe side effects resulting in poor compliance. Developing new anti-TB drug candidates is therefore of outmost importance. In this Special Issue dedicated to Tuberculosis Drug Discovery and Development, we present the main and latest achievements in the fields of drug and target discovery, host-directed therapy, anti-virulence drugs, and describe the development of two advanced compounds: macozinone and delpazolid. In addition, this Special Issue provides an historical perspective focused on Carlo Forlanini, the inventor of pneumothorax for TB treatment, and includes an overview of the state-of-the-art technologies which are being exploited nowadays in TB drug development. Finally, a summary of TB vaccines that are either approved or undergoing clinical trials concludes the Special Issue.

This open access book focuses on diagnostic and interventional imaging of the chest, breast, heart, and vessels. It consists of a remarkable collection of contributions authored by internationally respected experts, featuring the most recent diagnostic developments and technological advances with a highly didactical approach. The chapters are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions. As such, it presents a comprehensive review of current knowledge on imaging of the heart and chest, as well as thoracic interventions and a selection of "hot topics". The book is intended for radiologists, however, it is also of interest to clinicians in oncology, cardiology, and pulmonology.

A comprehensive textbook on tuberculosis that covers all aspects of the disease: epidemiology, microbiology, diagnosis, treatment, control and prevention. The main part of the book comprises very detailed and richly illustrated clinical chapters. The copious images are the advantage of this book. Chapters on new methods and treatments and on animal tuberculosis are included. The material is based on a wealth of experience in tuberculosis as seen in endemic countries such as Saudi Arabia that enjoy free access to advanced investigative and therapeutic facilities. This coexistence of endemicity of the disease and state-of-the-art facilities is rare in poor and developing countries or in rich and developed nations. This multidisciplinary volume is ideal for all clinicians, laboratory and research workers, epidemiologists, university teachers and students, health care planners and international organizations involved in world health and infectious disease.

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Medical Management of the Thoracic Surgery Patient, by Michael I. Lewis, MD and Robert J. McKenna, Jr., MD, is a comprehensive pulmonary and thoracic reference that takes a practical approach to the diagnosis, workup and care of the thoracic surgery patient. It is geared towards pulmonary and critical care physicians and their trainees as well as all other specialties with whom thoracic surgeons consult and interact. It outlines the principles for understanding the underlying disease entities as well as the clinical implications and complications of surgery, and interprets key surgical concepts such as correlative and functional anatomy for non-surgeons. Contributions from today’s authorities...“at-a-glance detailed key information, as well as summary bullets...and a multidisciplinary perspective, combine to offer essential guidance for confident patient management. As an Expert Consult title it includes convenient online access to the complete contents of the book—fully searchable—along with video clips of thoracic procedures, patient information sheets, all of the images downloadable for your personal use, and references linked to Medline at www.expertconsult.com. Includes access to a companion website at expertconsult.com where you can search the complete contents of the book, watch video clips of thoracic procedures, print out patient information sheets, download all of the images, and review references linked to Medline...providing you with a powerful resource for convenient consultation anytime, anywhere. Features ‘real world’ illustrative cases presented in a brief, bulleted format that facilitates easy access to and retention of the material. Examines every aspect of diagnosis and management for pre-, peri-, and postoperative care for an all-encompassing reference to respond to unique surgical problems. Provides coverage of individual topics supplemented by a brief case-based presentation, where appropriate, that lend a real-life perspective to the material. Contains all of the “need-to-know facts for a complete, thorough consultation in diagnosis and treatment of patients who undergo thoracic surgery. Offers practical information that utilizes the experience of today’s leaders while based on evidence in the literature for coverage you can trust. Examines current clinical controversies, providing you with an arena for discussion of sensitive topics and guidance on preferred approaches when relevant. Presents pearls, pitfalls, key points, and other learning elements in each chapter, to help you locate summaries of essential information “at-a-glance. Features chapters written by specialists of various disciplines, to equip you with a balanced perspective on each condition.