Stress-Activated Protein Kinases
Title | Stress-Activated Protein Kinases PDF eBook |
Author | Francesc Posas |
Publisher | Springer Science & Business Media |
Pages | 322 |
Release | 2008-01-24 |
Genre | Science |
ISBN | 3540755691 |
In this book leading researchers in the field discuss the state-of-the-art of many aspects of SAPK signaling in various systems from yeast to mammals. These include various chapters on regulatory mechanisms as well as the contribution of the SAPK signaling pathways to processes such as gene expression, metabolism, cell cycle regulation, immune responses and tumorigenesis. Written by international experts, the book will appeal to cell biologists and biochemists.
Signal Transduction and Protein Phosphorylation
Title | Signal Transduction and Protein Phosphorylation PDF eBook |
Author | L.M.G. Heilmeyer |
Publisher | Springer Science & Business Media |
Pages | 370 |
Release | 2012-12-06 |
Genre | Science |
ISBN | 1475701667 |
Signal Transduction
Title | Signal Transduction PDF eBook |
Author | Bastien D. Gomperts |
Publisher | Gulf Professional Publishing |
Pages | 450 |
Release | 2002-03-18 |
Genre | Medical |
ISBN | 9780122896316 |
Prologue: Signal transduction, origins and personalities. -- First messengers. -- Receptors. -- GTP-binding proteins and signal transduction. -- Effector enzymes coupled to GTP-binding proteins: adenylyl cyclase and phospholipase. -- The regulation of visual transduction. -- Calcium and signal transduction. -- Calcium signalling. -- Phosphorylation and dephosphorylation:protein kinases A and C. -- Growth Factors :setting the framework. -- Signalling pathways operated by receptor protein tyrosine kinases. -- Signalling pathways operated by non-receptor protein tyrosine kinases. -- Phosphoinositide 3-kinases. -- Signal transduction to and from adhesion molecules. -- Adhesion molecules and trafficking of leukocytes. -- Signalling through receptor bound protein serine-threonine kinases. -- Protein dephosphorylation and protein phosphorylation. -- Protein domains and signal transduction.
Cell Signal Transduction, Second Messengers, and Protein Phosphorylation in Health and Disease
Title | Cell Signal Transduction, Second Messengers, and Protein Phosphorylation in Health and Disease PDF eBook |
Author | A.M. Municio |
Publisher | Springer Science & Business Media |
Pages | 255 |
Release | 2012-12-06 |
Genre | Science |
ISBN | 1461518792 |
It is the great glory as it is also the great threat of science that everything which is in principle possible can be done if the intention to do it is sufficiently resolute. Peter Medawar, "The Threat and the Glory" An international symposium on "Cell Signal Transduction, Second Messengers, and Protein Phosphorylation in Health and Disease" was held at EI Escorial (Spain) from July 5-9, 1993 as a summer course of the Complutense University in Madrid. The lectures were delivered by renowned scientists from Europe, America, and Asia and attended by a large number of young scientists and graduate students from many countries. During evolution multicellular organisms have developed the most sophisticated and heterogeneous signals to maintain in harmony their multiple functions. The latest and most controversial aspects and developments in signal transduction were the main focus of this course. The communication among participants was extremely fluid, alive, and warm. This allowed the understanding of the key steps in cellular communication, from their original and historical sources to the main present hypothesis in the borderline of the latest scientific discoveries in this field. Without any doubt, the special atmosphere of the place, the monuments and the old granite stones, the "patio" with the fountain and the rose garden were responsible for the cordial meeting. This book comprises the manuscripts of the participants and we hope it will contribute to our knowledge of cellular signal transduction and be of value to a wider scientific community.
Signal Transduction
Title | Signal Transduction PDF eBook |
Author | Carl-Henrik Heldin |
Publisher | Garland Science |
Pages | 404 |
Release | 1996 |
Genre | Cell physiology |
ISBN | 9780748740741 |
Signal Transduction was published in association with The International Union of Biochemistry and Molecular Biology. In a series of twenty-three short chapters, leading researchers provide cutting-edge reviews of signal transduction, and form cell membrane receptors through to gene regulation. Written for those with a basic understanding of molecular and cell biology, the book will be of particular interest to graduate students and researchers who need to grasp the principles of signal transduction.
Protein Phosphorylation in Cell Growth Regulation
Title | Protein Phosphorylation in Cell Growth Regulation PDF eBook |
Author | Michael J. Clemens |
Publisher | CRC Press |
Pages | 300 |
Release | 1996-12-03 |
Genre | Medical |
ISBN | 9789057020308 |
The aim of this text is to integrate the processes of protein phosphorylation and dephosphorylation into the complex pathways by which cellular proliferation is driven, bringing together the many different systems of control implicated in the regulation of cell growth. Presents a survey of protein phosphorylation roles in the control of cellular proliferation and differentiation. A large number of protein kinases and phosphatases have been characterised in higher cells, and have been shown to be involved in signal transduction pathways by which growth factors, mitogens, and extracellular agents exert proliferative effects on cells. Important subjects covered include control of gene expression at the transcriptional and translational levels, and roles of the cdk kinases and cyclins in cell cycles regulation. Describes all major families of protein kinases of significance to growth regulation.
Protein Kinase-mediated Decisions Between Life and Death
Title | Protein Kinase-mediated Decisions Between Life and Death PDF eBook |
Author | Ayse Basak Engin |
Publisher | Springer Nature |
Pages | 415 |
Release | 2021-02-04 |
Genre | Medical |
ISBN | 3030498441 |
Protein phosphorylation via protein kinases is an inevitable process that alters physiological and pathological functions of the cells. Thus, protein kinases play key roles in the regulation of cell life or death decisions. Protein kinases are frequently a driving factor in a variety of human diseases including aging and cellular senescence, immune system and endothelial dysfunctions, cancers, insulin resistance, cholestasis and neurodegenerative diseases, as well as bacterial resistance in persistent infections. Recent developments in quantitative proteomics provide important opinions on kinase inhibitor selectivity and their modes of action in the biological context. Protein Kinase-mediated Decisions Between Life and Death aims to have the reader catch insights about up-to-date opinions on “Protein Kinases” related pathways that threaten human health and life. As “Protein Kinases” are related to many health problems, clinicians, basic science researchers and students need this information. Chapter “Signal Transduction in Immune Cells and Protein Kinases” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.