This PhD thesis focuses on the search for flavor-changing neutral currents in the decay of a top quark to an up-type quark (q = u, c) and the Standard Model Higgs boson, where the Higgs boson decays to bb. Further, the thesis presents the combination of this search for top quark pair events with other ATLAS searches – in the course of which the most restrictive bounds to date on tqH interactions were obtained. Following on from the discovery of the Higgs boson, it is particularly important to measure the Yukawa couplings of the Standard Model fermions; these parameters may provide crucial insights to help solve the flavor puzzle and may help reveal the presence of new physics before it is directly observed in experiments.

Squamous cell cancers of the head and neck (SCCHN), also known as head and neck cancers (HNC) encompass malignancies of the oral cavity, larynx, nasopharynx and pharynx, and are diagnosed in over 500,000 patients worldwide each year, accounting for 5% of all malignancies. It is estimated that approximately 50,000 patients develop head and neck cancer annually in the United States, of whom approximately 50% succumb to this cancer. For most cases of SCCHN, treatment is multimodal, often combining surgery or irradiation with chemotherapy; even successfully treated patients frequently experience durable and severe side effects. Improving cure rates and reducing chronic morbidity are urgent clinical needs for head and neck cancer. However, in contrast to cancer types such as breast or prostate that have been much studied and have well-defined biology, until recently, relatively few researchers investigated the molecular basis of HNC, making it difficult to design targeted treatments with better efficacy and less debilitating side effects. This volume will provide an overview of the factors contributing to disease pathogenesis, including the recognition of discrete molecular subtypes with distinct etiology, prognosis, and treatment response. This volume will familiarize the reader with the critical signaling pathways and oncogenic drivers for HNC. It will outline the differences between HPV-positive and HPV-negative disease, and how these differences affect treatment choice and outcome. The book will emphasize developments in the past five years, including the growing understanding of the genomic and epigenomic features of the disease based on analysis of next generation sequencing (NGS) data, and timely topics such as the analysis of HNC stem cell populations, non-coding mRNAs, and inflammatory response. It will address exciting new therapeutic approaches such as the use of immunotherapies to treat HNC patients. Overall, the book will provide the reader with current understanding of the biology and treatment of the disease, and describe timely questions that will guide future research aimed at controlling and curing this disease.

This practical guide covers the essential tasks in statistical data analysis encountered in high energy physics and provides comprehensive advice for typical questions and problems. The basic methods for inferring results from data are presented as well as tools for advanced tasks such as improving the signal-to-background ratio, correcting detector effects, determining systematics and many others. Concrete applications are discussed in analysis walkthroughs. Each chapter is supplemented by numerous examples and exercises and by a list of literature and relevant links. The book targets a broad readership at all career levels - from students to senior researchers. An accompanying website provides more algorithms as well as up-to-date information and links. * Free solutions manual available for lecturers at www.wiley-vch.de/supplements/

This book provides a self-contained description of the measurements of the magnetic dipole moments of the electron and muon, along with a discussion of the measurements of the fine structure constant, and the theory associated with magnetic and electric dipole moments. Also included are the searches for a permanent electric dipole moment of the electron, muon, neutron and atomic nuclei. The related topic of the transition moment for lepton flavor violating processes, such as neutrinoless muon or tauon decays, and the search for such processes are included as well. The papers, written by many of the leading authors in this field, cover both the experimental and theoretical aspects of these topics. Sample Chapter(s). Chapter 1: Historical Introduction to Electric and Mangnetic Moments (367 KB). Contents: Historical Introduction (B L Roberts); Electromagnetic Dipole Moments and New Physics (A Czarnecki & W J Marciano); Lepton g OCo 2 from 1947 to Present (T Kinoshita); Analytic QED Calculations of the Anomalous Magnetic Moment of the Electron (S Laporta & E Remiddi); Measurements of the Electron Magnetic Moment (G Gabrielse); Determining the Fine Structure Constant (G Gabrielse); Helium Fine Structure Theory for the Determination of (K Pachucki & J Sapirstein); Hadronic Vacuum Polarization and the Lepton Anomalous Magnetic Moments (M Davier); The Hadronic Light-by-Light Contribution to a, e (J Prades et al.); General Prescriptions for One-loop Contributions to a e, (K R Lynch); Measurement of the Muon ( g OCo 2) Value (J P Miller et al.); Muon ( g OCo 2) and Physics Beyond the Standard Model (D StAckinger); Probing CP Violation with Electric Dipole Moments (M Pospelov & A Ritz); The Electric Dipole Moment of the Electron (E D Commins & D DeMille); Neutron EDM Experiments (S K Lamoreaux & R Golub); Nuclear Electric Dipole Moments (W C Griffith et al.); EDM Measurements in Storage Rings (B L Roberts et al.); Models of Lepton Flavor Violation (Y Okada); Search for the Charged Lepton-Flavor-Violating Transition Moments l OaAE l OC (Y Kuno). Readership: Researchers and graduate students in particle physics, atomic physics and nuclear physics, as well as experts working in the field

Every night, William thinks up reasons why he shouldn't go to bed. One evening there is a very BIG reason -- someone has come to visit William. Will his parents believe him? Does William ever get to sleep? This delightful story about that tricky time at the end of every young family's day is guaranteed to make both child and parent smile!