As part of its scientific activities, the German Research Council on Smoking and Health regularly provides opportunities for scientists to discuss progress in the field of nicotine research. In this context, the Research Council sponsored a Satellite Symposium in Hamburg, June 28-30, 1990 entitled "Effects of Nicotine on Biological Systems". This meeting was held in conjunction with the XIth International Congress of Pharmacology in Amsterdam and follows the first Satellite Symposium on Nicotine which was convened in Brisbane, Australia in 1987. The aim of these conferences has been to discuss state of the art research on the pharmacology and toxicology of nicotine and its metabolites and to integrate this information to help define nicotinic actions on the central and peripheral nervous system as well as to evaluate health or behavioral effects associated with use of this alkaloid. Furthermore, at this conference, potential therapeutic benefits of nicotine for certain disease states were discussed. Smoking and the health effects of smoking were dealt with only as far as they could not be separated from the effects of nicotine. This volume contains the lectures presented at the symposium and illustrates that knowledge of nicotine has advanced considerably in recent years with regard to mechanisms of its actions. Despite such progress however, it is apparent that a' large number of questions remain unanswered, especially in the light of new insight into cellular and molecular mechanisms which can be affected by nicotine.

Written in the psychedelic era, Turn On, Tune In, Drop Out is Timothy Leary at his best, beckoning with humor and irreverence, a vision of individual empowerment, personal responsibility, and spiritual awakening. Includes: Start Your Own Religion Education as an Addictive Process Soul Session Buddha as Drop-Out Mad Virgin of Psychedelia God's Secret Agent o Homage to Huxley The Awe-Ful See-Er o The Molecular Revolution MIT is TIM Backwards Neurological Politics "Trickster is a major figure in American Indian folk Wisdom. Also in Sufi Tales … a certain type of "rascal"-with a grin and a wink (and wisdom beyond wisdom) … in the Zen tradition this is known as the School of Crazy Wisdom … Timothy Leary-in his own inimitable way-has become the twentieth century's grand master of crazy wisdom …" - Dr. Jeffrey Mishlove

Hallucinations, a natural phenomenon as old as mankind, have a surprisingly wide range. They appear under the most diversified conditions, in the "normal" psyche as well as in severe chronic mental derangement. As a symptom, hallucinations are a potential part of a variety of pathological conditions in almost all kinds of psychotic behavior. In addition, lately, various psychological and sociological circumstances seem to favor widespread use and abuse of hallucinogens, substances able to produce hallucinations in the normal brain. They not rarely lead to serious psychopatho logy such as toxic, and mobilized or aggravated endogenous psycho ses. While such development adds to our scientific knowledge, it also contributes to our current social troubles. Neurologists and neuro-surgeons, psychiatrists, psychologists and other specialized researchers constantly have been dealing with the phenomenon, its roots and branches, and yet, its primary mechanisms are largely un known. However, investigators of hallucinations now seem to enter common ground on which meaningful discussions and joint approaches become feasible and more promising. We have come a long way from the Latin term "hallucinari", meaning to talk nonsense, to be absent-minded, to the modern con cept of "hallucinations". While the Latin word was descriptive of what may be due to hallucinations, the modern concept defines hal lucinations as subjective experiences that are consequences of men tal processes, sometimes fulfilling a purpose in the individual's mental life.