This comprehensive review of a complex area is as much about women as it is about schizophrenia, encompassing the biological, endocrinological, epidemiological, reproductive, psychological and social aspects of schizophrenia as experienced by women. Femaleness impacts significantly on the onset and nature of schizophrenia suffered by women: the female brain develops more rapidly than the male; estrogens produce antipsychotic effects; the female brain ages differently from the male, with a massive preponderance of female very-late-onset schizophrenia which may be related to a relative excess of dopamine D2 receptors. An international, multidisciplinary team of clinicians and mental health researchers review past and current literature, assess the sex-specific issues and evaluate their therapeutic, clinical and social implications for more appropriate and effective treatments of schizophrenia in women now and in the future. It is essential reading for all clinicians, practitioners and researchers involved with mental health and also with women's health.

Interrogating the relationship between women and psychosis from a variety of perspectives, this edited collection explores personal, literary, spiritual, psychological, biological, and psychodynamic approaches. The contributors reflect on medieval mystics and witches, postpartum psychosis, disordered eating, art and literature, feminism, and male/female differences in schizophrenia. Women with experience of psychosis, psychotherapists, and a shaman provide first-person accounts to give the book a personal grounding. Curated with the intent to expand the way we think about women and psychosis, the contributors to this collection recognize that “voices and visions” do not occur in a vacuum, but are experienced within, and are influenced by, particular socio-cultural contexts.

Schizophrenic Women is a fascinating report on the lives of seventeen families that suffered the experiences associated with the hospitalization of the wife and mother for mental illness. A description and analysis of representative experiences is presented here in an attempt to investigate various key issues--the patterns of family living preceding the crisis leading to medical hospitalization; how the patterns fell apart; how personal and family crises became psychiatric emergencies; how the hospital experiences modified both the immediate crises and the earlier patterns of living--and how durable those changes were once the patients had returned home. The book goes beyond the immediate lives of the women and their families--the authors direct attention to patterns of psychiatric care and to the ways in which such crises as those experienced by these women and their families come to professional attention and are managed. The authors explore how help is found and used and some of the functions hospitalization serves for patients and their families. They point out some of the ways that traditional patterns of psychiatric care limit the power to observe, understand, and effectively influence a pathological course of events. In her new introduction to Schizophrenic Women, Rita J. Simon notes that, "Although the study was conducted in the 1950s, readers will recognize its current relevance and importance for scholars and the lay public interested in the problem of mental illness and intrafamily relationships."

#1 NEW YORK TIMES BESTSELLER • OPRAH’S BOOK CLUB PICK • ONE OF GQ's TOP 50 BOOKS OF LITERARY JOURNALISM IN THE 21st CENTURY • The heartrending story of a midcentury American family with twelve children, six of them diagnosed with schizophrenia, that became science's great hope in the quest to understand the disease. "Reads like a medical detective journey and sheds light on a topic so many of us face: mental illness." —Oprah Winfrey Don and Mimi Galvin seemed to be living the American dream. After World War II, Don's work with the Air Force brought them to Colorado, where their twelve children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins--aspiration, hard work, upward mobility, domestic harmony--and they worked hard to play their parts. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the ten Galvin boys, one after another, were diagnosed as schizophrenic. How could all this happen to one family? What took place inside the house on Hidden Valley Road was so extraordinary that the Galvins became one of the first families to be studied by the National Institute of Mental Health. Their story offers a shadow history of the science of schizophrenia, from the era of institutionalization, lobotomy, and the schizophrenogenic mother to the search for genetic markers for the disease, always amid profound disagreements about the nature of the illness itself. And unbeknownst to the Galvins, samples of their DNA informed decades of genetic research that continues today, offering paths to treatment, prediction, and even eradication of the disease for future generations. With clarity and compassion, bestselling and award-winning author Robert Kolker uncovers one family's unforgettable legacy of suffering, love, and hope.