This issue of the Psychiatric Clinics, edited by Dr. Peter F. Buckley, examines advances and current management in the treatment of Schizophrenia. The topics covered in this issue include, but are not limited to: Duration of Untreated Psychosis (DUP) and Longitudinal Perspectives on DUP; Neuroinflammation and Schizophrenia; Emerging Treatments for Schizophrenia; Treatment-Resistant Schizophrenia; Comorbidities and Schizophrenia; Recovery from Schizophrenia; and the latest in schizophrenia research.

This issue of the Psychiatric Clinics edited by Dr. John Beyer is dedicated to the topic of Bipolar Depression, from the genetics of the disorder, to the therapeutic options, to treatment in special populations. Articles in this issue include, but are not limited to: Differences in Bipolar and Unipolar Depression, Suicide and Bipolar Disorder, Social Relationships, Support, and Life Events in Bipolar Disorder, Treatment of Bipolar Depression in Pregnancy and the Post-Partum Period, Psychotherapy for Bipolar Depression, Cognition, Dementia, and Bipolar Depression, and Genetics of Bipolar Disorder.

Recent advances in clinical psychiatry are presented by David Baron and Lawrence Gross in this issue of Psychiatric Clinics. Psychiatrists will find here disorders they deal with daily in patients and topics include Advances in: Addictive disorders; Geriatric and healthy aging; Trauma and violence; PTSD; Schizophrenia; Intellectual disabilities; Neuropsychiatry, Psychopharmacology; Integrated care - psychiatry and primary care; Global and cultural psychiatry; Mood disorders. Also presented are the Future role of psychotherapy in psychiatry; Public mental health in the Affordable Care Act era; Genetics; and Diagnostic classification (DSM criteria) how they are transitioning in future - DSM V and beyond.

The strong association between mental health and sleep is examined here in topics that include: Epidemiology of sleep disorders, co-morbidity with mental health disorders and impact on health and quality of life; Neurobiology of sleep; Neurobiology of circadian rhythms; Genetics of sleep disorders; Sleep disturbances in anxiety disorders; Sleep disturbances in mood disorders; Sleep disturbances in schizophrenia; Sleep disturbances in substance abuse disorders; Sleep disturbances and behavioral disturbances in children and adolescents; Sleep disturbances and behavioral disturbances in the elderly; Sleep disturbances and behavioral symptoms in medical patients; Effects of psychotropic medications on sleep continuity and sleep architecture; Circadian rhythm sleep disorders; New developments in sleep medications of relevance to mental health disorders; and Primary sleep disorders: identification and treatment by psychiatrists.

This issue of Psychiatric Clinics, edited by Dr. James Knoll, is dedicated to violence and the psychological ramifications of violence in a wide array of situations. Subjects covered include, but are not limited to, violence by parents against children; gender and violence; lone wolf terrorists; inpatient violence; neuroimaging violence; workplace violence; gun violence; the military perspective on violence; homicides; suicides; sex offender risk and management; and psychopharmacology.

This issue of the Psychiatric Clinics of North America will review Clinical issues and Affirmative Treatments with Transgendered Clients. Edited by Lynne Carroll and lore m. dickey, subjects discussed in the text include, but are not limited to, Assessing Transgender and Gender Nonconforming Clients; Recommending Clients for Gender Transition; Psychodynamic Approaches in Clinical Practice with Gender Nonconforming and Gender Diverse Youth; Family Treatment with Transgender or Gender Nonconforming Children and Adolescents; Cognitive Behavioral Therapy with Transgender Adults; Therapeutic Issues with Transgender Elders; Hormonal and Surgical Treatment options; Transgender and Gender Diverse Clients with Co-Occurring Mental Disorders; DSM-V Coding; and Past and Future Challenges, among others.

This issue of the Psychiatric Clinics, edited by Dr. Rajnish Mago, will cover a variety of side effects of Psychopharmacotherapy. The topics discussed include principles of evaluation and management; sexual dysfunction; adverse effects on pregnancy due to bipolar medications; metabolic adverse effects of antipsychotics; adverse effects of psychotropic medications on sleep; antidepressants and suicide; and adverse effects of electroconvulsive therapies, among others.