The life of Nobel-winning biologist Salvador Luria, whose passion for science was equaled by his commitment to political engagement in Cold War America. Blacklisted from federal funding review panels but awarded a Nobel Prize for his research on bacteriophage, biologist Salvador Luria (1912–1991) was as much an activist as a scientist. In this first full-length biography of Luria, Rena Selya draws on extensive archival research; interviews with Luria’s family, colleagues, and students; and FBI documents obtained through the Freedom of Information Act to create a compelling portrait of a man committed to both science and society. In addition to his work with viruses and bacteria in the 1940s, Luria broke new ground in molecular biology and cancer research from the 1950s to the 1980s and was a leader in calling for scientists to accept an educational and advisory responsibility to the public. In return, he believed, the public should rely on science to strengthen social and political institutions. Luria was born in Italy, where the Fascists came to power when he was ten. He left Italy for France due to the antisemitic Race Laws of 1938, and then fled as a Jewish refugee from Nazi Europe, making his way to the United States. Once an American citizen, Luria became a grassroots activist on behalf of civil rights, labor representation, nuclear disarmament, and American military disengagement from the Vietnam and Gulf Wars. Luria joined the MIT faculty in 1960 and was the founding director of the Center for Cancer Research. Throughout his life he remained as passionate about his engagement with political issues as about his science, and continued to fight for peace and freedom until his death.

In Trying Biology, Adam R. Shapiro convincingly dispels many conventional assumptions about the 1925 Scopes “monkey” trial. Most view it as an event driven primarily by a conflict between science and religion. Countering this, Shapiro shows the importance of timing: the Scopes trial occurred at a crucial moment in the history of biology textbook publishing, education reform in Tennessee, and progressive school reform across the country. He places the trial in this broad context—alongside American Protestant antievolution sentiment—and in doing so sheds new light on the trial and the historical relationship of science and religion in America. For the first time we see how religious objections to evolution became a prevailing concern to the American textbook industry even before the Scopes trial began. Shapiro explores both the development of biology textbooks leading up to the trial and the ways in which the textbook industry created new books and presented them as “responses” to the trial. Today, the controversy continues over textbook warning labels, making Shapiro’s study—particularly as it plays out in one of America’s most famous trials—an original contribution to a timely discussion.

A welcome re-issue of an English translation of Alexander Luria's famous case-history of hypermnestic man. The study remains the classic paradigm of what Luria called 'romantic science,' a genre characterized by individual portraiture based on an assessment of operative psychological processes. The opening section analyses in some detail the subject's extraordinary capacity for recall and demonstrates the association between the persistence of iconic memory and a highly developed synaesthesia. The remainder of the book deals with the subject's construction of the world, his mental strengths and weaknesses, his control of behaviour and his personality. The result is a contribution to literature as well as to science. (Psychological Medicine ).

Leading scientists argue for a new paradigm for cancer research, proposing a complex systems view of cancer supported by empirical evidence. Current consensus in cancer research explains cancer as a disease caused by specific mutations in certain genes. After dramatic advances in genome sequencing, never before have we known so much about the individual cancer cell--and yet never before has it been so unclear what to do with this knowledge. In this volume, leading researchers argue for a new theory framework for understanding and treating cancer. The contributors propose a complex systems view of cancer, presenting conceptual building blocks for a new research paradigm supported by empirical evidence. The contributors first discuss the new research framework in terms of theoretical foundations and then take up the relevance of a systems approach, reviewing such topics as nonlinearity, recurrence after treatment, the cellular attractor concept, network theory, and non-coding DNA--the "dark matter" of our genome. They address the temporality of cancer progression, drawing on evolutionary theory and clinical experience. Finally, they cover the dominant role of the tissue microenvironment in cancer, analyzing topics including altered metabolic pathways, the disease-defining influence on metastasis, and the interconnectedness of different environmental niches across levels of organization.