The second edition was published in 2008, only two years after the first, but went out of print before a third edition could be prepared, so this revised version of the second edition is published to bridge the gap. Under the auspices of the Research Society for the Study of Diabetes in India, endocrinologists, immunologists, and other specialists present a broad reference on the disease of which India has more cases than any other country. After a review of landmarks in the history of diabetes, they cover physiology and metabolism, diagnosis and classification, epidemiology, etiopathogenesis of diabetes mellitus, genetics and immunology, clinical profile, management, co-morbid conditions, complications, diabetes through life and events, living with diabetes, health care delivery, and prevention. The two volumes are paged continuously, and both contain the combined index. Annotation ©2012 Book News, Inc., Portland, OR (booknews.com).

Diabetes mellitus is a group of metabolic diseases in which a person has high blood sugar, either because the body does not produce enough insulin, or because cells do not respond to the insulin that is produced. The latest edition of this reference provides endocrinologists with the latest advances in the diagnosis and management of diabetes. Beginning with an overview of epidemiology, pathophysiology and metabolism, the next sections discuss presentations of diabetes, therapeutic management, complications, and comorbidities. The following chapters cover diabetes in certain population groups, education and technology, nutrition, glucose monitoring, and research. The book concludes with a section dedicated to Type 1 diabetes, and a selection of journal reviews. Flow diagrams, tables and figures further enhance the comprehensive text. Key points Latest edition of comprehensive reference detailing latest advances in diagnosis and management of diabetes Covers numerous therapeutic methods Complete sections dedicated to Type 1 diabetes and journal reviews Highly illustrated with flow diagrams, tables and figures

Diabetes mellitus is a group of metabolic diseases in which a person has high blood sugar, either because the body does not produce enough insulin, or because cells do not respond to the insulin that is produced. The fourth edition of Textbook of Diabetes Mellitus has been fully revised to provide clinicians with the latest developments in the field. Divided into 19 sections, the book begins with discussion on the epidemiology, physiology and metabolism of the disease; its diagnosis and classification; and aetiopathogenesis, genetics and hormone action. The following sections cover types of diabetes, including in different segments of the population; clinical features and complications; diabetes with comorbidities; and management of the disease through both pharmacotherapy and non-pharmaceutical methods. Key points Fully revised new edition presenting latest advances in diagnosis and management of diabetes mellitus Covers diabetes in different population groups and with comorbidities Highly illustrated with clinical photographs, diagrams and tables Previous edition (9789351520900) published in 2014

Biochemistry, Biophysics, and Molecular Chemistry: Applied Research and Interactions provides the background needed in biophysics and molecular chemistry and offers a great deal of advanced biophysical knowledge. It emphasizes the growing interrelatedness of molecular chemistry and biochemistry, and acquaints one with experimental methods of both disciplines. This book addresses some of the enormous advances in biochemistry, particularly in the areas of structural biology and bioinformatics, by providing a solid biochemical foundation that is rooted in chemistry. Topics include scientific integrity and ethics in the field; clinical translational research in cancer, diabetes, and cardiovascular disease; emerging drugs to treat neurodegenerative diseases; swine, avian, and human flu; the use of big data in artificial knowledge in the field; bioinformatic insights on molecular chemistry; and much more.

The Sixth Edition of A Practical Guide to Diabetes Mellitus offers a unique combination of rigorous pathophysiology with very practical approaches to diabetes prevention and control. This outstanding textbook will equip a cadre of doctors and other health care professionals to deliver high quality care to vulnerable populations around India and far beyond. Based on research as well as clinical practice, the text describes diabetes in relation to physiology, ocular, cardiovascular, neuropathy, pregnancy, emergencies, childhood diabetes, etc. Each chapter beings with a brief outline of the disease concerned followed by introduction, definition/terminology, classification, treatment, conclusion and ending with set of question for self-assessment. Covers step wise images describes insulin administration in subcutaneous and using pen devices in the chapter: Insulin therapy: practical aspects. Feet, Footcare and Neuroarthropathy chapter deals with etiology and pathophysiology and is divided into three parts: Ulceration, Neuroarthropathy and Peripheral Artery Occlusive(PAD) diseases. Infection in diabetes chapter focuses on infection related to head and neck, genitourinary, skin and soft tissue, pulmonology and abdominal. Recent advances includes application of new drugs like Taspoglutide, Albiglutide, Lixisenatide, Newer DPP-IV inhibitors, along with new insulin receptor activators, PPAR agonists, new hepatic targets for glycemic control in diabetes. This book contains more than 300 coloured images and illustrations, 40 clinical cases, 50 questions for quick revision along with answers to the self-assessments question given at the end of book."

Despite considerable technological advances, the pharmaceutical industry is experiencing a severe innovation deficit, especially in the discovery of new drugs. Innovative Approaches in Drug Discovery: Ethnopharmacology, Systems Biology and Holistic Targeting provides a critical review and analysis of health, disease and medicine, and explores possible reasons behind the present crisis in drug discovery. The authors illustrate the benefits of systems biology and pharmacogenomics approaches, and advocate the expansion from disease-centric discovery to person-centric therapeutics involving holistic, multi-target, whole systems approaches. This book lays a path for reigniting pharmaceutical innovation through a disciplined reemergence of pharmacognosy, embracing open innovation models and collaborative, trusted public-private partnerships. With unprecedented advances made in the development of biomedically-relevant tools and technologies, the need is great and the time is now for a renewed commitment towards expanding the repertoire of medicines. By incorporating real-life examples and state-of-the-art reviews, this book provides valuable insights into the discovery and development strategies for professionals, academicians, and students in the pharmaceutical sciences. - Analyzes the reasons behind historical drug failures to provide valuable insights on lessons learned - Uses current scientific research to promote learning from traditional knowledge systems and through the integration of traditional and western medicines - Discusses advances in technologies and systems biology to support the transition from formulation discovery to therapeutic discovery