ROBERT VERBURG V CITY OF GRAND RAPIDS, 366 MICH 398 (1962)
Title | ROBERT VERBURG V CITY OF GRAND RAPIDS, 366 MICH 398 (1962) PDF eBook |
Author | |
Publisher | |
Pages | 40 |
Release | 1962 |
Genre | |
ISBN |
78
North western reporter. Second series. N.W. 2d. Cases argued and determined in the courts of Iowa, Michigan, Minnesota, Nebraska, North Dakota, South Dakota, Wisconsin
Title | North western reporter. Second series. N.W. 2d. Cases argued and determined in the courts of Iowa, Michigan, Minnesota, Nebraska, North Dakota, South Dakota, Wisconsin PDF eBook |
Author | |
Publisher | |
Pages | 1050 |
Release | 1962 |
Genre | |
ISBN |
Official Congressional Directory
Title | Official Congressional Directory PDF eBook |
Author | United States. Congress |
Publisher | Joint Committee on Printing |
Pages | 1258 |
Release | 2012-01-18 |
Genre | Biography & Autobiography |
ISBN |
Contains biographies of Senators, members of Congress, and the Judiciary. Also includes committee assignments, maps of Congressional districts, a directory of officials of executive agencies, addresses, telephone and fax numbers, web addresses, and other information.
Cyanobacterial Harmful Algal Blooms: State of the Science and Research Needs
Title | Cyanobacterial Harmful Algal Blooms: State of the Science and Research Needs PDF eBook |
Author | H. Kenneth Hudnell |
Publisher | Springer Science & Business Media |
Pages | 955 |
Release | 2008-03-13 |
Genre | Medical |
ISBN | 0387758658 |
With the ever-increasing incidence of harmful cyanobacterial algal blooms, this monograph has added urgency and will be essential reading for all sorts of researchers, from neuroscientists to cancer research specialists. The volume contains the proceedings of the 2005 International Symposium on Cyanobacterial Harmful Algal Blooms, and has been edited by H. Kenneth Hudnell, of the US Environmental Protection Agency. It contains much of the most recent research into the subject.
Marine Anthropogenic Litter
Title | Marine Anthropogenic Litter PDF eBook |
Author | Melanie Bergmann |
Publisher | Springer |
Pages | 456 |
Release | 2015-06-01 |
Genre | Science |
ISBN | 3319165100 |
This book describes how man-made litter, primarily plastic, has spread into the remotest parts of the oceans and covers all aspects of this pollution problem from the impacts on wildlife and human health to socio-economic and political issues. Marine litter is a prime threat to marine wildlife, habitats and food webs worldwide. The book illustrates how advanced technologies from deep-sea research, microbiology and mathematic modelling as well as classic beach litter counts by volunteers contributed to the broad awareness of marine litter as a problem of global significance. The authors summarise more than five decades of marine litter research, which receives growing attention after the recent discovery of great oceanic garbage patches and the ubiquity of microscopic plastic particles in marine organisms and habitats. In 16 chapters, authors from all over the world have created a universal view on the diverse field of marine litter pollution, the biological impacts, dedicated research activities, and the various national and international legislative efforts to combat this environmental problem. They recommend future research directions necessary for a comprehensive understanding of this environmental issue and the development of efficient management strategies. This book addresses scientists, and it provides a solid knowledge base for policy makers, NGOs, and the broader public.
Principles and Methods in Landscape Ecology
Title | Principles and Methods in Landscape Ecology PDF eBook |
Author | Almo Farina |
Publisher | Springer Science & Business Media |
Pages | 412 |
Release | 2008-01-22 |
Genre | Science |
ISBN | 1402055358 |
Landscape ecology is an integrative and multi-disciplinary science and Principles and Methods in Landscape Ecology reconciles the geological, botanical, zoological and human perspectives. In particular ,new paradigms and theories such as percolation, metapopulation, hierarchies, source-sink models have been integrated in this last edition with the recent theories on bio-complexity, information and cognitive sciences. Methods for studying landscape ecology are covered including spatial geometry models and remote sensing in order to create confidence toward techniques and approaches that require a high experience and long-time dedication. Principles and Methods in Landscape Ecology is a textbook useful to present the landscape in a multi-vision perspective for undergraduate and graduate students of biology, ecology, geography, forestry, agronomy, landscape architecture and planning. Sociology, economics, history, archaeology, anthropology, ecological psychology are some sciences that can benefit of the holistic vision offered by this texbook.
Integration of Pharmaceutical Discovery and Development
Title | Integration of Pharmaceutical Discovery and Development PDF eBook |
Author | Ronald T. Borchardt |
Publisher | Springer Science & Business Media |
Pages | 627 |
Release | 2006-01-19 |
Genre | Science |
ISBN | 0306473844 |
In the late 1980s, it became painfully evident to the pharmaceutical industry that the old paradigm of drug discovery, which involved highly segmented drug - sign and development activities, would not produce an acceptable success rate in the future. Therefore, in the early 1990s a paradigm shift occurred in which drug design and development activities became more highly integrated. This new str- egy required medicinal chemists to design drug candidates with structural f- tures that optimized pharmacological (e. g. , high affinity and specificity for the target receptor), pharmaceutical (e. g. , solubility and chemical stability), bioph- maceutical (e. g. , cell membrane permeability), and metabolic/pharmacokinetic (e. g. , metabolic stability, clearance, and protein binding) properties. Successful implementation of this strategy requires a multidisciplinary team effort, incl- ing scientists from drug design (e. g. , medicinal chemists, cell biologists, en- mologists, pharmacologists) and drug development (e. g. , analytical chemists, pharmaceutical scientists, physiologists, and molecular biologists representing the disciplines of pharmaceutics, biopharmaceutics, and pharmacokinetics/drug metabolism). With this new, highly integrated approach to drug design now widely utilized by the pharmaceutical industry, the editors of this book have provided the sci- tific community with case histories to illustrate the nature of the interdisciplinary interactions necessary to successfully implement this new approach to drug d- covery. In the first chapter, Ralph Hirschmann provides a historical perspective of why this paradigm shift in drug discovery has occurred.