So much of our lung health throughout life is determined by what happens before birth and when we are born. Managing respiratory problems in newborn infants requires experience and teamwork, an understanding of the background to the problems, and knowledge of the evidence behind the clinical options available. In this Monograph, science, evidence and expertise are brought together in a collection of comprehensive, state-of-the-art reviews that cover: the structure and function of the newborn respiratory system; neonatal lung disease in preterm infants; developmental, structural and functional diseases of the respiratory system; and more. This book will prove a valuable resource for neonatal clinicians, scientists researching the area and adult clinicians managing lung health.

Lung disease is a major indication for the admittance of the neonate to a specialist intensive care unit, and is a particularly common complication in the pre-term baby where the lungs are insufficiently developed at birth and easily damaged by early treatments. As a consequence, this is an area of intensive international research activity. In this comprehensive update of the well-received first edition, leading researchers from all over the world have been invited to contribute in their specialist areas. The book continues to provide detailed coverage of the pathogenesis, clinical and laboratory features and management of lung disorders in the neonate, with increased emphasis on the underlying immunology and major additions to the sections on respiratory support, chronic lung disease and abnormalities in lung growth and development to reflect the changes that have occurred in these areas since the previous edition appeared in 1995. Providing an unrivalled up-to-date statement on the problems that are faced in the neonatal intensive care unit on a daily basis, this is an invaluable addition to the bookshelves of neonatologists and other personnel involved in the care of critically ill babies.

Viral respiratory tract infections are important and common causes of morbidity and mortality worldwide. In the past two decades, several novel viral respiratory infections have emerged with epidemic potential that threaten global health security. This Monograph aims to provide an up-to-date and comprehensive overview of severe acute respiratory syndrome, Middle East respiratory syndrome and other viral respiratory infections, including seasonal influenza, avian influenza, respiratory syncytial virus and human rhinovirus, through six chapters written by authoritative experts from around the globe.

The Pocket Book is for use by doctors nurses and other health workers who are responsible for the care of young children at the first level referral hospitals. This second edition is based on evidence from several WHO updated and published clinical guidelines. It is for use in both inpatient and outpatient care in small hospitals with basic laboratory facilities and essential medicines. In some settings these guidelines can be used in any facilities where sick children are admitted for inpatient care. The Pocket Book is one of a series of documents and tools that support the Integrated Managem.

"Hypoxaemia is a major contributor to child deaths that occur worldwide each year; for a child with pneumonia hypoxaemia increases the risk of death by up to 5 times. Despite its importance in virtually all types of acute severe illness, hypoxaemia is often not well recognized or well managed, more so in settings where resources are limited. Oxygen therapy remains an inaccessible luxury for a large proportion of severely ill children admitted to hospitals in developing countries. This is particularly true for patients in small district hospitals, where, even if some facility for delivering oxygen is available, supplies are often unreliable and the benefits of treatment may be diminished by poorly maintained, inappropriate equipment or poorly trained staff with inadequate guidelines. Increasing awareness of these problems is likely to have considerable clinical and public health benefits in the care of severely ill children. Health workers should be able to know the clinical signs that suggest the presence of hypoxaemia and have more reliable means of detection of hypoxeamia. This can be achieved through more widespread use of pulse oximetry, which is a non-invasive measure of arterial oxygen saturation. At the same time oxygen therapy must be more widely available; in many remote settings, this can be achieved by use of oxygen concentrators, which can run on regular or alternative sources of power. Having effective systems for the detection and management of hypoxaemia are vital in reducing mortality from pneumonia and other severe acute illnesses. Oxygen therapy is essential to counter hypoxaemia and many times is the difference between life and death. This manual focuses on the availability and clinical use of oxygen therapy in children in health facilities by providing the practical aspects for health workers, biomedical engineers, and administrators. It addresses the need for appropriate detection of hypoxaemia, use of pulse oximetry, clinical use of oxygen and delivery systems and monitoring of patients on oxygen therapy. In addition, the manual addresses practical use of pulse oximetry, and oxygen concentrators and cylinders in an effort to improve oxygen systems worldwide."--Publisher's description.