Dry eye is one of the most common disorders encountered in ophthalmological practice. Its symptoms cause considerable discomfort and substantially reduce the patient’s quality of life. As it is a complex and multifactorial condition, research investigating dry eye is a matter of great interest all over the world.In this book, the wide range of current basic and clinical research in dry eye and correlated ocular surface diseases is presented by scientists from Germany, Austria and the USA. These renowned authors provide clear and extensive descriptions of their projects, enabling scientists and clinical ophthalmologists to quickly bring themselves up to date with cutting edge research in this field.This overview of research into the pathogenesis and clinical treatment of dry eye is a must for all ophthalmologists dealing with this syndrome and looking to increase their knowledge base.

During the past several decades, a significant international research effort has been directed towards understanding the composition and regulation of the preocular tear film. This effort has been motivated by the recognition that the tear film plays a critical role in maintaining corneal and conjunctival integrity, protecting against microbial challenge and preserving visual acuity. In addition, research has been stimulated by the knowledge that alteration or deficiency of the tear film, which occurs in numerous individuals throughout the world, may lead to desiccation of the ocular surface, ulceration and perforation of the cornea, an increased incidence of infectious disease, and potentionally pronounced visual disability and blindness.

Ocular Surface Disease: Cornea, Conjunctiva and Tear Film incorporates current research and the latest management strategies as well as classification systems and treatment paradigms for all forms of ocular surface disease. This is the first comprehensive resource that helps you to meet ocular surface disease challenges effectively using today's best medical and surgical approaches. Get the complete, evidence-based guidance you need to provide optimal care for your patients with ocular surface disease. Implement the latest drug treatments and surgical interventions to provide better outcomes with fewer complications. Hone and expand your surgical skills by watching videos of leading experts performing advanced procedures including ocular surface transplantation techniques; amniotic membrane transplantation; pterygium surgery; lamellar keratoplasty (DALK) in ocular surface disease; and keratoprosthesis surgery. Visualize how to proceed by reviewing detailed, full-color images and consulting new classification systems and treatment paradigms for mild to severe forms of ocular surface disease. Take it with you anywhere! Access the full text, downloadable image library, video clips, and more online at expertconsult.com.

Current knowledge of the epidemiology, clinical expression, pathophysiology and available medical and surgical therapy for ocular surface diseases, providing an invaluable text for ocular surface specialists, general ophthalmologists, optometrists and residents.

A number of structures contribute to tear production and maintenance, including the tear system, the lids and the orbit. The ocular surface itself is also a part of the system, including the cornea and conjunctiva. This makes for a very complex situation that can easily lead to changes in tear film and the ocular surface that are called "dry eye." Here a team of experts carefully examine how and when surgery is indicated, addressing normal tear film, normal anatomy (including immunological interactions), classification and diagnosis, anti-inflammatory and immnunosup-pressive concepts, correction and drainage techniques, surgery of the conjunctiva and cornea, keratoprosthesis surgery, botulism toxin injections, mucous membrane grafting, and salivary gland transplantation along with other treatments. The collection closed with a set of scientific studies. The color and monochrome clinical photographs and line illustrations are especially well-chosen and informative.

There has been considerable increase in the knowledge concern ing tear secretion, the ocular surface, and pathophysiologic con ditions leading to the dry eye. Much of this new knowledge is not widely appreciated. Although there have been proceedings of symposia published, there is no currently available book of suf ficient scope, yet reasonable length, which ties together aspects of this newly acquired knowledge. This textbook is designed to give the ophthalmic practitioner a comprehensive, yet concise, guide line concerning the diagnosis and treatment of the dry eye. We have been able to bring together leading researchers to accom plish the same. We wish to express our special thanks to the company Dr. Mann Pharma of Berlin without whose generous sponsorship we could not have completed our task. The sponsor ship, in bringing together the authors in planning, preparation, and realization of this text, is gratefully acknowledged. Washington/Ulm, March 1992 M. A. Lemp R. Marquardt Contents Introduction 1 Chapter 1 History of the Dry Eye J. Murube . . . . . 3 1 lntroduction 3 2 The Concept of the Dry Eye 5 3 The History of the Causes of the Dry Eye 6 4 The History of the Diagnosis of the Dry Eye 11 5 The History of the Treatment of the Dry Eye 15 6 The Social Response to the Dry Eye 19 References . . . . . . . . . . . . . . . . 19 Chapter 2 Functional Morphology of the Conjunctiva J. W. Rohen and E. Lütjen-Drecoll. With 20 Figures and 3 Tables . . . . . . . . . 35 1 Conjunctiva . . . . . . . .

This easy-to-read introduction to the role of the visual system in the workplace is designed to help many professional ergonomists and human resources professionals to appreciate more fully the relationship between good vision and the efficiency and safety of job performance. It is an accessible account which is illustrated with both low level draw