The book comprises of different chapters associated with methodology in Plant science (Botany), describing in a simple and comprehensive way. The importance of creativity and motivation in research, the planning and proposal of research project, the description of different techniques involved in research are described in an elaborate way. It also includes the sources/collection of scientific information, method of scientific report/paper/thesis writing etc. The book is also a source of different aspects of research methodology in plant science dealt with in a comprehensive manner tailored to the needs of postgraduate students/research scholars for easy understanding. The book is profusely illustrated. The different chapters described in the book include: Introduction, Microscopy, Plant micro-technique, Smear/Sqush technique, Plant tissue culture, Herbarium technique, Hydrogen ion concentration (pH), Centrifugation, Chromatography, Electrophoresis, Colorimetry, Spectro-photometry, Radio-isotopes in biology and Computers and their application in plant sciences. Chapters on Biostatistics, Biophysics and Bioinformatics have also been included to help the student in the statistical analysis of the results, physical principles involved in the operation of different instruments and basics of bioinformatics. We sincerely hope that this book helps to fill up the lacuna and provides what all that is needed about the research methods required for a scholar/student in plant sciences to pursue their higher studies.