Report on the State of the Blood and the Blood-vessels in Inflammation, and on Other Points Relating to the Circulation in the Extreme Vessels
Title | Report on the State of the Blood and the Blood-vessels in Inflammation, and on Other Points Relating to the Circulation in the Extreme Vessels PDF eBook |
Author | Thomas Wharton Jones |
Publisher | |
Pages | 84 |
Release | 1891 |
Genre | Blood-vessels |
ISBN |
Report On The State Of The Blood And The Blood-vessels In Inflammation, And On Other Points Relating To The Circulation In The Extreme Vessels
Title | Report On The State Of The Blood And The Blood-vessels In Inflammation, And On Other Points Relating To The Circulation In The Extreme Vessels PDF eBook |
Author | Thomas Wharton Jones |
Publisher | Sagwan Press |
Pages | 82 |
Release | 2015-08-27 |
Genre | |
ISBN | 9781340463250 |
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Report on the State of the Blood and the Blood-vessels in Inflammation
Title | Report on the State of the Blood and the Blood-vessels in Inflammation PDF eBook |
Author | Thomas Wharton Jones |
Publisher | |
Pages | |
Release | 1891 |
Genre | |
ISBN |
Inflammation and the Microcirculation
Title | Inflammation and the Microcirculation PDF eBook |
Author | D. Neil Granger |
Publisher | Morgan & Claypool Publishers |
Pages | 99 |
Release | 2010 |
Genre | Medical |
ISBN | 1615041656 |
The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References
Report on the state of the blood and the blood-vessels in inflammation
Title | Report on the state of the blood and the blood-vessels in inflammation PDF eBook |
Author | Thomas Wharton Jones |
Publisher | |
Pages | 67 |
Release | 1891 |
Genre | |
ISBN |
Report on the State of the Blood and the Blood-vessels in Inflammation ... Together with a Report on Lymphatic Hearts and on the Propulsion of Lymph from Them, Though a Proper Duct, Into Their Respective Veins
Title | Report on the State of the Blood and the Blood-vessels in Inflammation ... Together with a Report on Lymphatic Hearts and on the Propulsion of Lymph from Them, Though a Proper Duct, Into Their Respective Veins PDF eBook |
Author | Thomas Wharton JONES (F.R.S.) |
Publisher | |
Pages | 67 |
Release | 1891 |
Genre | |
ISBN |
Inflammatory Diseases of Blood Vessels
Title | Inflammatory Diseases of Blood Vessels PDF eBook |
Author | Gary S. Hoffman |
Publisher | John Wiley & Sons |
Pages | 597 |
Release | 2012-04-10 |
Genre | Medical |
ISBN | 111835527X |
Inflammatory Diseases of Blood Vessels“/b> Inflammatory Diseases of Blood Vessels Second Edition Inflammatory Diseases of Blood Vessels provides a comprehensive overview of the science and clinical consequences of vascular inflammation in health and disease. In recent years, considerable progress has been made in understanding different forms of vasculitis. Investigation of pathogenesis of vascular inflammation has led to improved treatments and outcomes. Surgical and transplant procedures have improved in parallel with medical therapies. These areas are extensively examined in this new edition. Inflammatory Diseases of Blood Vessels is an excellent resource for a broad readership, including clinicians, investigators and their support teams in numerous specialties e.g. rheumatology, immunology, cardiology, cardiovascular surgery, pulmonary medicine, nephrology, pathology, vascular biology, embryology and imaging.