Accompanying CD-ROM contains ... "150 color images with legends, 472 book figures with legends, 438 multiple choice test questions, and 119 interactive drag-and-drop exercises." -- from CD-ROM Welcome screen.

This book provides a detailed update on our knowledge of dental pulp and regenerative approaches to therapy. It is divided into three parts. The pulp components are first described, covering pulp cells, extracellular matrix, vascularization and innervation as well as pulp development and aging. The second part is devoted to pulp pathology and includes descriptions of the differences between reactionary and reparative dentin, the genetic alterations leading to dentinogenesis imperfecta and dentin dysplasia, the pulp reaction to dental materials, adverse impacts of bisphenol A and the effects of fluorosis, dioxin and other toxic agents. The final part of the book focuses on pulp repair and regeneration. It includes descriptions of various in vitro and in vivo (animal) experimental approaches, definition of the pulp stem cells with special focus on the stem cell niches, discussion of the regeneration of a living pulp and information on new strategies that induce pulp mineralization.

"Fundamentals of Tissue Engineering and Regenerative Medicine" provides a complete overview of the state of the art in tissue engineering and regenerative medicine. Tissue engineering has grown tremendously during the past decade. Advances in genetic medicine and stem cell technology have significantly improved the potential to influence cell and tissue performance, and have recently expanded the field towards regenerative medicine. In recent years a number of approaches have been used routinely in daily clinical practice, others have been introduced in clinical studies, and multitudes are in the preclinical testing phase. Because of these developments, there is a need to provide comprehensive and detailed information for researchers and clinicians on this rapidly expanding field. This book offers, in a single volume, the prerequisites of a comprehensive understanding of tissue engineering and regenerative medicine. The book is conceptualized according to a didactic approach (general aspects: social, economic, and ethical considerations; basic biological aspects of regenerative medicine: stem cell medicine, biomolecules, genetic engineering; classic methods of tissue engineering: cell, tissue, organ culture; biotechnological issues: scaffolds; bioreactors, laboratory work; and an extended medical discipline oriented approach: review of clinical use in the various medical specialties). The content of the book, written in 68 chapters by the world’s leading research and clinical specialists in their discipline, represents therefore the recent intellect, experience, and state of this bio-medical field.

• Incorporates all relevant changes especially in the field of molecular biology • Discusses molecular biological aspects of oral tissues • Emphasizes clinical relevance of oral histological aspects • contains more line diagrams and illustrations for easier understanding

Find the latest evidence-based research and clinical treatments! Cohen's Pathways of the Pulp, 11th Edition covers the science, theory, and practice of endondontics with chapters written by internationally renowned experts. Full-color illustrations and detailed radiographs guide you through each step of endodontic care - from diagnosis and treatment planning to proven techniques for managing pulpal and periapical diseases. New to the print edition are seven new chapters, and the eBook version adds three more. As an Expert Consult title, Cohen's Pathways of the Pulp lets you search the entire contents of the book on your desktop or mobile device, and includes videos, case studies, and more. Edited by noted specialists Kenneth Hargreaves and Louis Berman, this book is the definitive resource in endodontics! Print version of the text includes 27 comprehensive chapters and meets the CODA requirements for endodontic dental education. EBook version of the text consists of 30 searchable chapters, including the 27 chapters in the print version, and features videos, PowerPoint® slides, review questions, case studies, and more; this expanded version makes it easy to find clinical answers quickly, and meets the needs of students, clinicians, and residents in endodontics. Videos and animations demonstrate key procedures such as palpation of the masseter muscle, introsseous anesthesia with the X-tipT system, dentin hypersensitivity, indirect ultrasound, palpation of the temporomandibular joint, and ultrasonic settling. Over 2,000 illustrations include full-color photos and line art, along with a wide range of radiographs, clearly demonstrating core concepts and reinforcing the essential principles and techniques of endodontics. NEW co-editor Dr. Louis H. Berman joins lead editor Dr. Kenneth M. Hargreaves for this edition, and a respected team of contributors includes experts from many U.S.-based dental education programs, as well as programs in Canada, the U.K., Norway, Sweden, France, Germany, Italy, and Switzerland. NEW chapter organization reflects the chronology of endodontic treatment with three comprehensive sections: Clinical Endodontics, focusing on core clinical concepts, and Biological Basis of Endodontics and Endodontics in Clinical Practice, both with information that advanced students, endodontic residents, and clinicians need to know. NEW! Three chapters are available in the eBook: Understanding and Managing the Anxious Patient, Endodontic Records and Legal Responsibilities, and Endodontic Practice Management. NEW Radiographic Interpretation chapter clarifies the diagnostic process with coverage of imaging modalities, diagnostic tasks, three-dimensional imaging, cone beam computed tomography, intra- or post-operative assessment of endodontic treatment complications, and more. NEW Pain Control chapter addresses the management of acute endodontic pain with coverage of local anesthesia for restorative dentistry and endodontics, along with nonnarcotic analgesics and therapeutic recommendations. NEW Evaluation of Outcomes chapter helps you achieve optimal treatment outcomes with information on topics such as the reasons for evaluating outcomes, outcome measurements for endodontic treatment, and the outcomes of vital pulp therapy procedures, non-surgical root canal treatment, non-surgical retreatment, and surgical retreatment. NEW Root Resorption chapter covers the early detection, diagnosis, and histological features of root resorption, as well as external inflammatory resorption, external cervical resorption, and internal resorption. NEW Iatrogenic Endodontics chapter addresses failed treatment scenarios with key information on the event itself, the etiology, soft and hard tissue implications and symptoms, and treatment options and prognosis; the events include cervico-facial subcutaneous emphysema, sodium hypochlorite accidents, perforations (non-surgical), inferior alveolar nerve injury, surgical, sinus perforation, instrument separation, apical extrusion of obturation materials, and ledge formation. NEW Vital Pulp Therapy chapter provides an overview of new treatment concepts for the preservation of the pulpally involved permanent tooth, covering topics such as the living pulp, pulpal response to caries, procedures for generating reparative dentin, indications and materials for vital pulp therapy, MTA applications, and treatment recommendations. NEW Bleaching chapter addresses procedures that can be utilized during and following endodontic treatment to eliminate or reduce any discoloration issues, reviewing internal and external bleaching procedures and their impact on pulpal health/endodontic treatment - with presentations of cases and clinical protocols.

The definitive endodontics reference, Cohen’s Pathways of the Pulp is known for its comprehensive coverage of leading-edge information, materials, and techniques. It examines all aspects of endodontic care, from preparing the clinician and patient for endodontic treatment to the role the endodontist can play in the treatment of traumatic injuries and to the procedures used in the treatment of pediatric and older patients. Not only does Hargreaves and Cohen’s 10th edition add five chapters on hot new topics, it also includes online access! As an Expert Consult title, Cohen’s Pathways of the Pulp lets you search the entire contents of the book on your computer, and includes five online chapters not available in the printed text, plus videos, a searchable image collection, and more. For evidence-based endodontics research and treatment, this is your one-stop resource!