Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

This short text addresses complications of regional anesthesia and pain medicine. Each chapter is written by an expert in the area and follows a strict format: Definition of the complication, Scope of the problem, Pathophysiology or proposed mechanism of causation, Risk factors, Diagnostic evaluation, Prevention, Treatment and rehabilitation, Summary. Emphasis in each chapter is placed around what levels of evidence the recommendations in the chapter carry. The complications covered in regional anesthesia include complications in neuraxis and peripheral nerve blocks. There is also a section on complications associated with unintended local anesthetic destinations. The complications in pain medicine include complications of acute pain management, of sympathetic blocks, of neuraxis approaches and device placement. The first edition was published by Elsevier. They have returned copyright to Rathmell and Neal, who will turn it over to us. The audience includes anesthesiologists, pain medicine specialists, and neurologists.

This textbook provides an overview of pain management useful to specialists as well as non-specialists, surgeons, and nursing staff.

This book provides a precise description of safe and reliable procedures for regional anesthesia in children. It covers the advantages and disadvantages, specific features related to the pediatric range of ages, and the practical importance of the described procedures. Written in two main parts, emphasis is placed on scientific basis and technical approach. It includes both anatomical and psychological aspects of pain, as well as detailed viewpoints of parents, children, surgeons, and anesthetists. This book is a must for all anesthesiologists and will be particularly useful to students of medicine and anesthesiology and nurses working with intensive care units.

Perioperative Pain Management is an up-to-date, evidence-based guide for clinicians who diagnose and treat post-surgical patients.