This book presents regenerative strategies for the treatment of knee joint disabilities. The book is composed of four main sections totaling 19 chapters which review the current knowledge on the clinical management and preclinical regenerative strategies. It examines the role of different natural-based biomaterials as scaffolds and implants for addressing different tissue lesions in the knee joint. Section one provides an updated and comprehensive discussion on articular cartilage tissue regeneration. Section two focuses on the important contributions for bone and osteochondral tissue engineering. Section three overview the recent advances on meniscus repair/regeneration strategies. Finally, section four further discusses the current strategies for treatment of ligament lesions. Each chapter is prepared by world know expert on their fields, so we do firmly believe that the proposed book will be a reference in the area of biomaterials for regenerative medicine.

Advances in Biomedical Polymers and Composites: Materials and Applications is a comprehensive guide to polymers and polymer composites for biomedical applications, bringing together detailed information on their preparation, properties, cutting-edge technologies, innovative materials and key application areas. Sections introduce polymers and composites in biomedical applications and cover characterization techniques, preparation and properties of composites and gel-based systems. Innovative technologies and instruments used in the fabrication of polymer composites for biomedical applications are then presented in detail, including 3D bioprinting, 4D printing, electrospinning, stimuli-responsive polymers and quantum dots. This is a valuable resource for anyone looking to gain a broader understanding of polymers and composites for biomedical applications. In addition, it is ideal for readers who want to conduct interdisciplinary research or explore new avenues for research and development. Provides broad, systematic and detailed coverage of preparation methods, properties, technologies, structures and applications Explores the state-of-the-art in biomedical polymers, including gene delivery, oleogels, bigels, 3D bioprinting, 4D printing and antiviral materials Offers analysis and comparison of experimental data on physical properties and explains environmental, ethical and medical guidelines

The Social Security Administration (SSA) administers two programs that provide disability benefits: the Social Security Disability Insurance (SSDI) program and the Supplemental Security Income (SSI) program. SSDI provides disability benefits to people (under the full retirement age) who are no longer able to work because of a disabling medical condition. SSI provides income assistance for disabled, blind, and aged people who have limited income and resources regardless of their prior participation in the labor force. Both programs share a common disability determination process administered by SSA and state agencies as well as a common definition of disability for adults: "the inability to engage in any substantial gainful activity by reason of any medically determinable physical or mental impairment which can be expected to result in death or which has lasted or can be expected to last for a continuous period of not less than 12 months." Disabled workers might receive either SSDI benefits or SSI payments, or both, depending on their recent work history and current income and assets. Disabled workers might also receive benefits from other public programs such as workers' compensation, which insures against work-related illness or injuries occurring on the job, but those other programs have their own definitions and eligibility criteria. Selected Health Conditions and Likelihood of Improvement with Treatment identifies and defines the professionally accepted, standard measurements of outcomes improvement for medical conditions. This report also identifies specific, long-lasting medical conditions for adults in the categories of mental health disorders, cancers, and musculoskeletal disorders. Specifically, these conditions are disabling for a length of time, but typically don't result in permanently disabling limitations; are responsive to treatment; and after a specific length of time of treatment, improve to the point at which the conditions are no longer disabling.

Cartilage, Tissue and Knee Joint Biomechanics: Fundamentals, Characterization and Modelling is a cutting-edge multidisciplinary book specifically focused on modeling, characterization and related clinical aspects. The book takes a comprehensive approach towards mechanics, fundamentals, morphology and properties of Cartilage Tissue and Knee Joints. Leading researchers from health science, medical technologists, engineers, academics, government, and private research institutions across the globe have contributed to this book. This book is a very valuable resource for graduates and postgraduates, engineers and research scholars. The content also includes comprehensive real-world applications. As a reference for the total knee arthroplasty, this book focuses deeply on existing related theories (including: histology, design, manufacturing and clinical aspects) to assist readers in solving fundamental and applied problems in biomechanical and biomaterials characterization, modeling and simulation of human cartilages and cells. For biomedical engineers dealing with implants and biomaterials for knee joint injuries, this book will guide you in learning the knee anatomy, range of motion, surgical procedures, physiological loading and boundary conditions, biomechanics of connective soft tissues, type of injuries, and more. Provides a comprehensive resource on the knee joint and its connective soft tissues; content included spans biomechanics, biomaterials, biology, anatomy, imaging and surgical procedure Covers ISO and FDA based regulatory control and compliance in the manufacturing process Includes discussions on the relationship between knee anatomical parameters and knee biomechanics

This book reviews the most recent developments in the field of osteochondral tissue engineering (OCTE) and presents challenges and strategies being developed that face not only bone and cartilage regeneration, but also establish osteochondral interface formation in order to translate it into a clinical setting. Topics include nanotechnology approaches and biomaterials advances in osteochondral engineering, advanced processing methodology, as well as scaffolding and surface engineering strategies in OCTE. Hydrogel systems for osteochondral applications are also detailed thoroughly. Osteochondral Tissue Engineering: Nanotechnology, Scaffolding-Related Developments and Translation is an ideal book for biomedical engineering students and a wide range of established researchers and professionals working in the orthopedic field.

This book, featuring a practical hands-on format, describes an up-to-date and comprehensive approach to the management of complex knee injuries. The aim is both to equip practitioners with reliable expert guidance and to foster consensus in a field characterized by continuing debate. Initial response and diagnostic evaluation are explained, surgical techniques appropriate for different injuries are fully documented, and advice is provided on the response to injuries in specific scenarios and patient groups. Emphasis is placed on the vital role of precise diagnosis in establishing the optimal treatment approach, and full account is taken of the implications of the most recent anatomical and biomechanical data. Readers will also find recommendations on controversial topics, including the role of early surgical management, the use of autograft or allograft tissue, and the benefits of reconstruction (as opposed to repair alone) of the fibular collateral ligament and posterolateral corner structures. The authors are leading authorities from around the world with extensive clinical and research expertise in the field of knee dislocations.