This book is about the recognition of new principles in Organic Chemistry. It is also about the discovery and invention of Chemical Reactions. In addition, it deals with the determination of structure by chemical degradation during the epoch when physical methods were not well developed. Also presented are new reagents and new types of functional groups never seen in chemistry before. The overall aim of the collected papers is to show how thought can direct original research and to demonstrate how thought about old or new chemical facts can lead to originality. This is further illuminated by commentaries which Prof Barton has written to accompany these papers.

These papers discuss the recognition of new principles in organic chemistry and the discovery and invention of chemical reactions. They also present new reagents and new types of functional groups never seen in chemistry before

This invaluable book distils the research accomplishments of Professor Fred Basolo during the five decades when he served as a world leader in the modern renaissance of inorganic chemistry. Its primary focus is on the very important area of chemistry known as coordination chemistry.Most of the elements in the periodic table are metals, and most of the chemistry of metals involves coordination chemistry. This is the case in the currently significant areas of research, including organometallic homogenous catalysis, biological reactions of metalloproteins, and even the solid state extended structures of new materials. In these systems, the metals are of primary importance because they are the sites of ligand substitution or redox reactions. In the solid materials, the coordination number of the metal and its stereochemistry are of major importance.Some fifty years of research on transition metal complexes carried out in the laboratory of Professor Basolo at Northwestern University is recorded here as selected scientific publications. The book is divided into three different major research areas, each dealing with some aspect of coordination chemistry. In each case, introductory remarks are presented which indicate what prompted the research projects and what the major accomplishments were. Although the research was of the academic, curiosity-driven type, some aspects have proven to be useful to others involved in projects that were much more applied in nature.

Chemical physics is presently a very active field, where theoretical computation and accurate experimentation have led to a host of exciting new results. Among these are the possibility of state-to-state reactive scattering, the insights in non-adiabatic chemistry, and, from the computational perspective, the use of explicitly correlated functions in quantum chemistry. Many of these present-day developments use ideas, derivations and results that were obtained in the very early days of quantum theory, in the 1920s and 1930s.Much of this material is hard to study for readers not familiar with German. This volume presents English translations of some of the most important papers. The choice of material is made with the relevance to present-day researchers in mind. Included are seminal papers by M Born and J R Oppenheimer, J von Neumann and E Wigner, E A Hylleraas, F London, F Hund, H A Kramers, R de L Kronig and F Hückel, among others.

The selected papers in this invaluable volume are arranged in chapters, each with an introductory essay. The purpose of the arrangement is to illustrate the process of scientific discovery at work. Neil Bartlett's field is that of powerful oxidizers. The early chapters tell the story of the oxidation of the oxygen molecule and the discovery of xenon chemistry. His work in noble-gas chemistry is summarized. Succeeding chapters show how metastable fluorides such as Ag3 and NiF4 came to be prepared at ordinary temperatures and pressures, and how they have provided the most potent oxidizers and fluorinators ever prepared.

Pt. III. Biological macromolecules. ch. 11. Hemoglobin: Oxygen bonding and magnetic properties papers SP 82 to SP -- ch. 12. Antibodies: Structure and function papers SP 88 to SP 94 -- ch. 13. The alpha helix and the structure of proteins papers SP 95 to SP 111 -- ch. 14. Molecular biology: The role of large molecules in life and evolution papers SP 112 to SP 121 -- pt. IV. Health and medicine. ch. 15. Molecular disease papers SP 122 to SP 126 -- ch. 16. Physiological chemistry, effects of radiation, and health hazards papers SP 127 to SP 133 -- ch. 17. Orthomolecular medicine papers SP 134 to SP 144 -- pt. V. Summary of Linus Pauling's life and scientific work. ch. 18. Biographical memoir, by Prof. Jack D. Dunitz

Linus Pauling wrote a stellar series of over 800 scientific papers spanning an amazing range of fields, some of which he himself initiated. This book is a selection of the most important of his writings in the fields of quantum mechanics, chemical bonding (covalent, ionic, metallic, and hydrogen bonding), molecular rotation and entropy, protein structure, hemoglobin, molecular disease, molecular evolution, the antibody mechanism, the molecular basis of anesthesia, orthomolecular medicine, radiation chemistry/biology, and nuclear structure. Through these papers the reader gets a fresh, unfiltered view of the genius of Pauling's many contributions to chemistry, chemical physics, molecular biology, and molecular medicine.