Modern computer-intensive statistical methods play a key role in solving many problems across a wide range of scientific disciplines. This new edition of the bestselling Randomization, Bootstrap and Monte Carlo Methods in Biology illustrates the value of a number of these methods with an emphasis on biological applications. This textbook focuses on three related areas in computational statistics: randomization, bootstrapping, and Monte Carlo methods of inference. The author emphasizes the sampling approach within randomization testing and confidence intervals. Similar to randomization, the book shows how bootstrapping, or resampling, can be used for confidence intervals and tests of significance. It also explores how to use Monte Carlo methods to test hypotheses and construct confidence intervals. New to the Third Edition Updated information on regression and time series analysis, multivariate methods, survival and growth data as well as software for computational statistics References that reflect recent developments in methodology and computing techniques Additional references on new applications of computer-intensive methods in biology Providing comprehensive coverage of computer-intensive applications while also offering data sets online, Randomization, Bootstrap and Monte Carlo Methods in Biology, Third Edition supplies a solid foundation for the ever-expanding field of statistics and quantitative analysis in biology.

Randomization, Bootstrap and Monte Carlo Methods in Biology, Second Edition features new material on on bootstrap confidence intervals and significance testing, and incorporates new developments on the treatments of randomization methods for regression and analysis variation, including descriptions of applications of these methods in spreadsheet programs such as Lotus and other commercial packages. This second edition illustrates the value of modern computer intensive methods in the solution of a wide range of problems, with particular emphasis on biological applications. Examples given in the text include the controversial topic of whether there is periodicity between co-occurrences of species on islands.

Designed for a one-semester advanced undergraduate or graduate course, Statistical Theory: A Concise Introduction clearly explains the underlying ideas and principles of major statistical concepts, including parameter estimation, confidence intervals, hypothesis testing, asymptotic analysis, Bayesian inference, and elements of decision theory. It introduces these topics on a clear intuitive level using illustrative examples in addition to the formal definitions, theorems, and proofs. Based on the authors’ lecture notes, this student-oriented, self-contained book maintains a proper balance between the clarity and rigor of exposition. In a few cases, the authors present a "sketched" version of a proof, explaining its main ideas rather than giving detailed technical mathematical and probabilistic arguments. Chapters and sections marked by asterisks contain more advanced topics and may be omitted. A special chapter on linear models shows how the main theoretical concepts can be applied to the well-known and frequently used statistical tool of linear regression. Requiring no heavy calculus, simple questions throughout the text help students check their understanding of the material. Each chapter also includes a set of exercises that range in level of difficulty.

Exercises and Solutions in Statistical Theory helps students and scientists obtain an in-depth understanding of statistical theory by working on and reviewing solutions to interesting and challenging exercises of practical importance. Unlike similar books, this text incorporates many exercises that apply to real-world settings and provides much mor

This package includes both Mathematical Statistics: Basic Ideas and Selected Topics, Volume I, Second Edition, as well as Mathematical Statistics: Basic Ideas and Selected Topics, Volume II. Volume I presents fundamental, classical statistical concepts at the doctorate level without using measure theory. It gives careful proofs of major results and explains how the theory sheds light on the properties of practical methods. Volume II covers a number of topics that are important in current measure theory and practice. It emphasizes nonparametric methods which can really only be implemented with modern computing power on large and complex data sets. In addition, the set includes a large number of problems with more difficult ones appearing with hints and partial solutions for the instructor.

Calculations once prohibitively time-consuming can be completed in microseconds by modern computers. This has resulted in dramatic shifts in emphasis in applied statistics. Not only has it freed us from an obsession with the 5% and 1% significance levels imposed by conventional tables but many exact estimation procedures based on randomization tests are now as easy to carry out as approximations based on normal distribution theory. In a wider context it has facilitated the everyday use of tools such as the bootstrap and robust estimation methods as well as diagnostic tests for pinpointing or for adjusting possible aberrations or contamination that may otherwise be virtually undetectable in complex data sets. Data Driven Statistical Methods provides an insight into modern developments in statistical methodology using examples that highlight connections between these techniques as well as their relationship to other established approaches. Illustration by simple numerical examples takes priority over abstract theory. Examples and exercises are selected from many fields ranging from studies of literary style to analysis of survival data from clinical files, from psychological tests to interpretation of evidence in legal cases. Users are encouraged to apply the methods to their own or other data sets relevant to their fields of interest. The book will appeal both to lecturers giving undergraduate mainstream or service courses in statistics and to newly-practising statisticians or others concerned with data interpretation in any discipline who want to make the best use of modern statistical computer software.

With numerous examples using SAS PROC GLIMMIX, this text presents an introduction to linear modeling using the generalized linear mixed model as an overarching conceptual framework. For readers new to linear models, the book helps them see the big picture. It shows how linear models fit with the rest of the core statistics curriculum and points out the major issues that statistical modelers must consider.