This issue of Anesthesiology Clinics focuses on Quality Improvement and Implementation Science, with topics including: Applying implementation science principles to perioperative care; Emergency checklists in perioperative care; Human factors applied to perioperative process improvement; Handoffs in perioperative care; Use of simulation in performance improvement; Developing capacity to do improvement science work; Developing multicenter registries to advance quality science; Rethinking clinical workflow; data-driven quality improvement; and Scaling quality improvement at the health system level.

This issue of Anesthesiology Clinics, guest edited by Dr. Alexander A. Hannenberg, focuses on Management of Critical Events. This is one of four issues each year selected by the series consulting editor, Dr. Lee Fleisher. Articles in this issue include, but are not limited to: Why We Fail to Rescue from Critical Events; High Fidelity Simulation Training; Alternatives to High Fidelity Simulation Training; Tools to Improve our Capacity to Rescue; Use of Cognitive Aids to Improve Management of Critical Events; Real-time debriefing after critical events: Exploring the Gap between Principle and Reality; Mass Casualty Events; Obstetrical Hemorrhage; Intraoperative cardiac arrest; The Lost Airway; The Septic Patient and Oxygen Supply Failure.

In this issue of Anesthesiology Clinics, guest editors Drs. Alison J. Brainard and Lyndsay M. Hoy oversee the topic of Total Well-being. Articles in this issue highlight perspectives from across multiple subsets of anesthesiology, including nutrition, arts and humanities, coaching, and the inequalities of medicine. The editors’ goal is that readers will come away inspired, informed, and excited to create an approach for total well-being that can be tailored to their workplace and lives. Contains 19 practice-oriented topics including women in anesthesiology; parenting/lactation in anesthesia; intensivists and wellness, post-pandemic; early-career physician burnout; integrating antiracism into MedEd with health humanities program; and more. Provides in-depth clinical reviews on total well-being, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Anesthesiology Clinics focuses on Anesthesia Out of the Operating Room. Editors Mark Weiss and Wendy Gross have assembled an expert team of authors on topics such as: A Changing Landscape: Demands of Integrated Care Delivery: Interventional Medicine and Anesthesiology: Engineering Challenges and Interdisciplinary Teamwork; Organizational Infrastructure: Attaining and Teaching Clinical Excellence. Improvement across specialties by implementing an “Institute mentality in the clinical arena; Quality: Who’s rules apply?; Electronic Health Records; Monitoring; Interventional Radiology (NOT RADIATION): (Safety/Tumor Ablation/Adult radiology/ equipment); Approaches to Vascular Disease; Cath Lab: Structural Heart Disease, Devices and TAVR; EP Lab; Cardioversions and TEEs; Upper GI EGD and new procedures; Colonoscopy and new procedures anesthesiologist and GI person; Endoscopic Surgery, repair of surgical procedures, bariatric procedures; Interventional Pulmonology; Pediatrics; Market Evaluation; Finances, Bundled Payments and ACOs; Competitive Strategy or Joint Venture Finance: potential threats and likely future scenarios.

In this issue of Anesthesiology Clinics, guest editors Drs. Matthew M. McEvoy and James Abernathy III bring their considerable expertise to the topic of Perioperative Safety Culture. Safety culture is the product of individual and group values, attitudes, perceptions, competencies, and patterns of behavior that determine an organization’s health and safety management. In this issue, top experts discuss topics such as patient safety and clinician wellness; handoffs and In-hospital care transitions; team dynamics in the operating room: how is team performance optimized?; anesthesiology operating room medication delivery; OR design: state-of-the-art design concepts to help mitigate errors and improve safety; and more. Contains 16 practice-oriented topics including perioperative safety culture: principles, practices, and pragmatic approaches; what do we know about the system and what are the best practices to stop errors in healthcare; coaching to improve performance; systems of care delivery and optimization in the preoperative arena, operating room, ICU, and postoperative care wards; and more. Provides in-depth clinical reviews on perioperative safety culture, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

The Institute of Medicine's Forum on the Science of Health Care Quality Improvement and Implementation held a workshop on January 16, 2007, in Washington, DC. The workshop had its roots in an earlier forum meeting when forum members discussed what is meant by the terms "quality improvement" and "implementation science" and became convinced that they mean different things to different people. At the time, the members also discussed the need to identify barriers to quality improvement research and to implementation science. Thus the purpose of this workshop was to bring people together from various arenas to discuss what quality improvement is, and what barriers exist in the health care industry to quality improvement and also to research about quality improvement. The summary that ensues is thus limited to the presentations and discussions during the workshop itself. We realize that there is a broader scope of issues pertaining to this subject area but are unable to address them in this summary document. The workshop's first session was devoted to experiences that various institutions have had with quality improvement. Recognizing the wealth of experiences available outside of health care services, the workshop included presenters from outside the health care service industry as well as from inside. This includes discussions from a variety of perspectives: non-health care services, health plans, hospitals, and nursing. Advancing Quality Improvement Research: Challenges and opportunities - Workshop Summary describes the events of the workshop.

This issue of Anesthesiology Clinics focuses on Pharmacology. Editor Alan Kaye has assembled an expert team of authors on topics such as: Ketorolac, Oxymorphone and Tapentadol; Anticoagulation and Neuraxial/Peripheral Anesthesia; Pharmacologic Update on Antiemetics: Total parenteral nutrition/enteral nutrition in the ICU, Evolving Concepts; Reversal of Anticoagulants and Anesthesia Considerations; Non-opioids Intravenous or Oral Analgesics for Perioperative Pain Management, Update; Uterotonic Medications and Anesthesia Considerations: oxytocin, misoprostol, methylergonovine, carboprost; Pulmonary Vascular Mediating Drugs, Evolving Concepts; Alpha 2 Modulators and Anesthesia Considerations; Pharmacologic Considerations of Anesthetic Agents in the Obese Patient; Pharmacologic Considerations of Anesthetic Agents in the Geriatric Patient; Pharmacologic Considerations of Anesthetic Agents in the Pediatric Patient; Anesthesia CV Drug Update; Pharmacogenomics: Anesthesia; Pharmacogenomics: Pain; Novel anticoagulants; Novel anesthetic agents; Novel opioids; Pharmacology of Newer Local anesthetics; Pharmacology of Nonsteroidal Antiinflammatory and Steroid Medications. Implications for Anesthesia or Unique Associated Risks; Pharmacology of Octreotide. Implications for Anesthesia and Associated Risks.