Prevention of Alzheimer’s Disease: From Cognitive Reserve to Precision Medicine

Prevention of Alzheimer’s Disease: From Cognitive Reserve to Precision Medicine
Title Prevention of Alzheimer’s Disease: From Cognitive Reserve to Precision Medicine PDF eBook
Author Hyun Kook Lim
Publisher Frontiers Media SA
Pages 99
Release 2020-08-05
Genre
ISBN 2889639177

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The Alzheimer's Prevention and Treatment Diet

The Alzheimer's Prevention and Treatment Diet
Title The Alzheimer's Prevention and Treatment Diet PDF eBook
Author Richard S. Isaacson, MD
Publisher Square One Publishers, Inc.
Pages 251
Release 2016-05-19
Genre Health & Fitness
ISBN 0757054080

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​*** OVER 13,000 COPIES SOLD *** SEEN NATIONWIDE ON ​THE DR. OZ SHOW​ Increasingly, research has shown that diet is one of the greatest weapons we have to protect and defend your rain against Alzheimer’s disease (AD). Based on current studies as well as firsthand experience working with thousands of patients—both those who have normal cognitive health and those in the early stages of Alzheimer’s—The Alzheimer’s Prevention & Treatment Diet provides a cutting-edge nutritional program that can help reduce the risk for AD and may slow its progress if it has already developed. This book: * Presents a nine-week diet plan that gradually introduces brain-healthy foods and dietary strategies. * Guides you in making smart lifestyle choices, from exercise to hobbies, that strengthen cognitive health. * Explores nutritional supplements that can support the brain and prevent cognitive decline. * Offers suggestions for managing the special nutritional needs of loved ones with AD. * Explains the medications used to treat AD—what they are, what they do, and how they should be used. * Provides sample full-day menus, including breakfast, lunch, dinner, and snacks. * Presents lists of recommended foods to make meal planning easy. Whatever your age, now is the perfect time to start adopting a brain-healthy lifestyle. The Alzheimer’s Prevention and Treatment Diet guides you in making changes that can significantly enhance your cognitive well-being—now and for a lifetime.

The End of Alzheimer's

The End of Alzheimer's
Title The End of Alzheimer's PDF eBook
Author Dale Bredesen
Publisher Penguin
Pages 322
Release 2017-08-22
Genre Health & Fitness
ISBN 0735216207

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The instant New York Times and Wall Street Journal bestseller A groundbreaking plan to prevent and reverse Alzheimer’s Disease that fundamentally changes how we understand cognitive decline. Everyone knows someone who has survived cancer, but until now no one knows anyone who has survived Alzheimer's Disease. In this paradigm shifting book, Dale Bredesen, MD, offers real hope to anyone looking to prevent and even reverse Alzheimer's Disease and cognitive decline. Revealing that AD is not one condition, as it is currently treated, but three, The End of Alzheimer’s outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger "downsizing" in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications like taking B12, eliminating gluten, or improving oral hygiene. The results are impressive. Of the first ten patients on the protocol, nine displayed significant improvement with 3-6 months; since then the protocol has yielded similar results with hundreds more. Now, The End of Alzheimer’s brings new hope to a broad audience of patients, caregivers, physicians, and treatment centers with a fascinating look inside the science and a complete step-by-step plan that fundamentally changes how we treat and even think about AD.

Reducing the Impact of Dementia in America

Reducing the Impact of Dementia in America
Title Reducing the Impact of Dementia in America PDF eBook
Author National Academies of Sciences Engineering and Medicine
Publisher
Pages
Release 2022-04-26
Genre
ISBN 9780309495035

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As the largest generation in U.S. history - the population born in the two decades immediately following World War II - enters the age of risk for cognitive impairment, growing numbers of people will experience dementia (including Alzheimer's disease and related dementias). By one estimate, nearly 14 million people in the United States will be living with dementia by 2060. Like other hardships, the experience of living with dementia can bring unexpected moments of intimacy, growth, and compassion, but these diseases also affect people's capacity to work and carry out other activities and alter their relationships with loved ones, friends, and coworkers. Those who live with and care for individuals experiencing these diseases face challenges that include physical and emotional stress, difficult changes and losses in their relationships with life partners, loss of income, and interrupted connections to other activities and friends. From a societal perspective, these diseases place substantial demands on communities and on the institutions and government entities that support people living with dementia and their families, including the health care system, the providers of direct care, and others. Nevertheless, research in the social and behavioral sciences points to possibilities for preventing or slowing the development of dementia and for substantially reducing its social and economic impacts. At the request of the National Institute on Aging of the U.S. Department of Health and Human Services, Reducing the Impact of Dementia in America assesses the contributions of research in the social and behavioral sciences and identifies a research agenda for the coming decade. This report offers a blueprint for the next decade of behavioral and social science research to reduce the negative impact of dementia for America's diverse population. Reducing the Impact of Dementia in America calls for research that addresses the causes and solutions for disparities in both developing dementia and receiving adequate treatment and support. It calls for research that sets goals meaningful not just for scientists but for people living with dementia and those who support them as well. By 2030, an estimated 8.5 million Americans will have Alzheimer's disease and many more will have other forms of dementia. Through identifying priorities social and behavioral science research and recommending ways in which they can be pursued in a coordinated fashion, Reducing the Impact of Dementia in America will help produce research that improves the lives of all those affected by dementia.

GeNeDis 2020

GeNeDis 2020
Title GeNeDis 2020 PDF eBook
Author Panayiotis Vlamos
Publisher Springer Nature
Pages 391
Release 2022-01-01
Genre Medical
ISBN 3030787710

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The 4th World Congress on Genetics, Geriatrics and Neurodegenerative Diseases Research (GeNeDis 2020) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific advances, with the aim of better, safer, and healthier aging. The increase in the average length of life leads to the development of various diseases in the elderly population. This volume focuses on the sessions from the conference on Geriatrics.

Preventing Cognitive Decline and Dementia

Preventing Cognitive Decline and Dementia
Title Preventing Cognitive Decline and Dementia PDF eBook
Author National Academies of Sciences, Engineering, and Medicine
Publisher National Academies Press
Pages 181
Release 2017-10-05
Genre Medical
ISBN 0309459591

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Societies around the world are concerned about dementia and the other forms of cognitive impairment that affect many older adults. We now know that brain changes typically begin years before people show symptoms, which suggests a window of opportunity to prevent or delay the onset of these conditions. Emerging evidence that the prevalence of dementia is declining in high-income countries offers hope that public health interventions will be effective in preventing or delaying cognitive impairments. Until recently, the research and clinical communities have focused primarily on understanding and treating these conditions after they have developed. Thus, the evidence base on how to prevent or delay these conditions has been limited at best, despite the many claims of success made in popular media and advertising. Today, however, a growing body of prevention research is emerging. Preventing Cognitive Decline and Dementia: A Way Forward assesses the current state of knowledge on interventions to prevent cognitive decline and dementia, and informs future research in this area. This report provides recommendations of appropriate content for inclusion in public health messages from the National Institute on Aging.

Sex and Gender Differences in Alzheimer's Disease

Sex and Gender Differences in Alzheimer's Disease
Title Sex and Gender Differences in Alzheimer's Disease PDF eBook
Author Maria Teresa Ferretti
Publisher Academic Press
Pages 514
Release 2021-07-23
Genre Medical
ISBN 012819345X

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Sex and Gender Differences in Alzheimer's Disease: The Women's Brain Project offers for the first time a critical overview of the evidence documenting sex and gender differences in Alzheimer's disease neurobiology, biomarkers, clinical presentation, treatment, clinical trials and their outcomes, and socioeconomic impact on both patients and caregivers. This knowledge is crucial for clinical development, digital health solutions, as well as social and psychological support to Alzheimer's disease families, in the frame of a precision medicine approach to Alzheimer's disease.This book brings together up-to-date findings from a variety of experts, covering basic neuroscience, epidemiology, diagnosis, treatment, clinical trials development, socioeconomic factors, and psychosocial support. Alzheimer's disease, the most common form of dementia, remains an unmet medical need for the planet. Wide interpersonal variability in disease onset, presentation, and biomarker profile make Alzheimer's a clinical challenge to neuroscientists, clinicians, and drug developers alike, resulting in huge management costs for health systems and society. Not only do women represent the majority of Alzheimer's disease patients, but they also represent two-thirds of caregivers. Understanding sex and gender differences in Alzheimer's disease will lead to novel insights into disease mechanisms, and will be crucial for personalized disease management strategies and solutions, involving both the patient and their family. Endorsements/Reviews: "There is a clear sex and gender gap in outcomes for brain health disorders like Alzheimer's disease, with strikingly negative outcomes for women. This understanding calls for a more systematic way of approaching this issue of inequality. This book effectively highlights and frames inequalities in all areas across the translational spectrum from bench-to-bedside and from boardroom-to-policy and economics. Closing the Brain Health Gap will help economies create recovery and prepare our systems for future global shocks." Harris A. Eyre MBBS, PhD, co-lead, Neuroscience-inspired Policy Initiative, OECD and PRODEO Institute. Instructor in Brain Health Diplomacy, Global Brain Health Institute, UCSF and TCD. "Sex and Gender Differences in Alzheimer's disease is the most important title to emerge on Alzheimer's disease in recent years.This comprehensive, multidisciplinary book is a must read for anyone with a serious interest in dementia prevention, diagnosis, treatment, care, cure and research. Precision medicine is the future of healthcare and this book represents an incredible and necessary resource to guide practice, policy and research in light of the fact that Alzheimer's disease disproportionately affects women. The combination of contributions from the most eminent experts and the most up-to-date research makes this an invaluable resource for clinicians, care providers, academics, researchers and policy makers. Given the complex nature of dementia and the multiple factors that influence risk and disease trajectory the scope of the book is both impressive and important covering sex differences in neurobiological processes, sex and gender differences in clinical aspects and gender differences linked to socioeconomic factors relevant to Alzheimer's disease. If you work in Alzheimer's disease, or indeed other dementias, then Sex and Gender Differences in Alzheimer's disease is a must have for your bookshelf." -- Sabina Brennan, PhD., C.Psychol.,PsSI., National representative for Ireland on Alzheimer Disease International's Medical and Scientific Advisory Panel