This is an open access title available under the terms of a CC BY-NC 4.0 International licence. It is free to read at Oxford Scholarship Online and offered as a free PDF download from OUP and selected open access locations. Before new interventions are released into disease control programmes, it is essential that they are carefully evaluated in field trials'. These may be complex and expensive undertakings, requiring the follow-up of hundreds, or thousands, of individuals, often for long periods. Descriptions of the detailed procedures and methods used in the trials that have been conducted have rarely been published. A consequence of this, individuals planning such trials have few guidelines available and little access to knowledge accumulated previously, other than their own. In this manual, practical issues in trial design and conduct are discussed fully and in sufficient detail, that Field Trials of Health Interventions may be used as a toolbox' by field investigators. It has been compiled by an international group of over 30 authors with direct experience in the design, conduct, and analysis of field trials in low and middle income countries and is based on their accumulated knowledge and experience. Available as an open access book via Oxford Medicine Online, this new edition is a comprehensive revision, incorporating the new developments that have taken place in recent years with respect to trials, including seven new chapters on subjects ranging from trial governance, and preliminary studies to pilot testing.

The Department of Health and Human Services has identified Acquired Immunodeficiency Syndrome (AIDS) as the foremost public health problem in the United States. The Centers for Disease Control (CDC) report that, as of December 31, 1994, there were 441,528 documented cases of AIDS in this country, and the number is increasing. AIDS is an illness characterized by a defect in natural immunity against disease. Many more individuals are known to be infected with Human Immunodeficiency Virus (HIV) but do not have symptoms or the defming characteristics of AIDS. The incubation period for AIDS may range from 1 to 10 or more years in adults and 6 months to several years in children. Infected persons appear to be capable of transmitting infection indefinitely, even if they remain asymptomatic. In order to increase the number of minority investigators conducting research on HIV infection and 1 AIDS, NIMH conducted a 3h-day technical workshop for minority investigators on July 24-27. 1990, in Fairlakes, Virginia. University-based research programs were asked to nominate investigators who were selected on the basis of a referred 1 0-page prospectus for a proposed research project. This procedure was used because NIMH wanted to be sure that the prospective investigators were established in a research environment that would pr

A Practical Guide to Writing a Ruth L. Kirschstein NRSA Grant provides F-Series grant applicants and mentors with insider knowledge on the process by which these grants are reviewed, the biases that contribute to the reviews, the extent of information required in an NRSA training grant, a deeper understanding of the exact purpose of each section of the application, and key suggestions and recommendations on how to best construct each and every section of the application. A Practical Guide to Writing a Ruth L. Kirschstein NRSA Grant is a solid resource for trainees and their mentors to use as a guide when constructing F30, F31, and F32 grant applications. - Covers F30, F31, and F32 grant applications - Detailed overview of the review process - Key suggestions on how to best construct each section of the application - Includes a checklist of required items

This fully updated and revised edition of a classic guide to grant writing for health and human service professionals reflects the two major changes in the field: new NIH application processes and an increased emphasis on interprofessional and team approaches to science. New case examples reflect grant writing strategies for a great variety of health and human service professions, and the text includes an enhanced focus on online methods for organizing grant submissions. A new section on special considerations for submitting grants addresses specific types of research including community-based participatory research, mixed methods, behavioral intervention research, and dissertation and , mentorship proposals. The new chapter on common writing challenges and solutions provides examples of strong and weak statements and highlights the importance of writing with precision. Additionally, this new edition provides an expanded section on post-award requirements and links to NIH videos about grant writing. Written for individuals in both academic and practice settings, the guide addresses, step-by-step, the fundamental principles for effectively securing funding. It is the only book to provide grant-writing information that encompasses many disciplines and to focus on building a research career with grant writing as a step-by-step process. It provides detailed, time-tested strategies for building an investigative team, highlights the challenges of collaboration, and describes how to determine the expertise needed for a team and the roles of co-investigators. The book addresses the needs of both novice and more experienced researchers. New to the Fourth Edition: Reflects recent changes to the field including an emphasis on interprofessional approaches to science and new NIH application processes Offers additional case examples relevant to social work, nursing, psychology, rehabilitation, and occupational, physical, and speech therapies Provides links to NIH websites containing videos on grant writing Includes chapter opener objectives Expands section on post-award requirements Focuses on electronic mechanisms for organizing grant submissions