Exploring fundamental concepts, Drug Delivery Nanoparticles Formulation and Characterization presents key aspects of nanoparticulate system development for various therapeutic applications and provides advanced methods used to file for regulatory approval.This comprehensive guide features:Process Analytical Techniques (PAT) used in manufacturing Na

The book deals with the synthesis and characterization of hydrogels specifically used as drug delivery systems. Each chapter includes the most recent updates about the different starting materials employed and the improvement of their physicochemical and biological properties to synthetize high performing carriers for specific uses.

Nanosuspensions; osmotic pumps; viscosity; pump position; in-vitro-in-vivo evaluation; radioimaging

This book introduces the reader to drug delivery with specific emphasis on the use of nanoparticles. It covers properties, characterization, and preparation of different types of nanoparticles and discusses recent advances in their structural design and biomedical application, as well as the issues and challenges associated with their design and use. Some of the topics covered include the potential application of nanoparticles in biomedical fields, hazards associated with use of nanoparticles for drug delivery, size-dependent factors in drug delivery applications, different organic, inorganic and their hybrid systems used in drug delivery, etc. It also highlights use of nanoparticles in controlled and targeted drug delivery, and their application in stimuli-responsive, especially pH-responsive, drug release. Additionally, it also focuses on biomimetic nanoparticles, challenges faced in the designing of nanoparticles for drug delivery in cancer, viral and bacterial diseases. The contents of this volume will be useful to researchers and professionals working on advances in targeted drug delivery systems.

The synthesis and characterization of nanocomposites for drug delivery applications is an emerging field that aims to develop safe and effective drug delivery systems with enhanced therapeutic efficacy. Nanocomposites are composed of different types of nanoparticles, polymers, and other materials that can be precisely engineered to achieve specific drug delivery goals. These materials are typically biocompatible and biodegradable, allowing for controlled release of drugs over an extended period of time. The synthesis and characterization of nanocomposites involve the preparation of the nanoparticles and their subsequent incorporation into the polymer matrix or other material. Different types of nanoparticles, such as magnetic nanoparticles, gold nanoparticles, carbon nanotubes, and lipid-based nanoparticles, can be utilized depending on the intended application. Surface modification techniques can be employed to enhance the stability, biocompatibility, and specificity of the nanocomposites for targeted drug delivery. Characterization of nanocomposites is crucial to understanding their physicochemical properties, drug-loading capacity, and drug release kinetics. Techniques such as dynamic light scattering, scanning electron microscopy, transmission electron microscopy, X-ray diffraction, and Fourier-transform infrared spectroscopy can be used to characterize the nanocomposites. The use of nanocomposites for drug delivery applications has several advantages, including improved drug solubility, enhanced bioavailability, and reduced toxicity. Moreover, the development of stimuli-responsive nanocomposites that respond to changes in environmental factors such as pH, temperature, and magnetic field can further enhance drug delivery efficacy. The synthesis and characterization of nanocomposites for drug delivery applications represent a promising approach for the development of safe and effective drug delivery systems with enhanced therapeutic efficacy. However, further studies are needed to optimize the design of nanocomposites and to assess their toxicity and biocompatibility. Nanomaterial has promising application of all technology development. Nanomaterial has one or more dimension in the nanometer scale (100 nm) range and subsequently show novel properties from their bulk materials. Nanotechnology, led by the development of nanoparticles (NPs) -based drug delivery systems and imaging contrast agents, has had an important role in diagnosis, prevention, and treatment of the disease. The use of nanotechnology for cancer therapy and imaging is expected to overcome the limitations of conventional treatments, such as poor drug bioavailability, nonspecific systemic drug distribution, inadequate drug concentrations reaching the tumor and inability to monitor therapeutic responses in real time.