This succinct yet comprehensive volume describes current and emerging concepts in molecular pathology of bladder cancer. Divided into two distinct sections, the first part focuses on the general principles of molecular findings in bladder cancer, while the second part focuses on the molecular changes associated with specific histologic subtypes. The volume also addresses such topics as molecular alterations in non-invasive and invasive disease, including bladder cancer variants as appropriate, emerging molecular classifiers of bladder cancer, and molecular associations to outcome and treatment. Written by experts in the field, Precision Molecular Pathology of Bladder Cancer is a valuable resource for those in the urologic community, including urologic pathologists, urologists, urologic oncologists and radiation oncologists, who treat and manage bladder cancer.

The human urinary bladder is subject to a unique and extraordinarily diverse array of congenital, inflammatory, metaplastic, and neoplastic abnormalities. This book provides contemporary, comprehensive, and evidence-based practice information for pathologists, urologists, oncologists, and other medical professionals. In Bladder Pathology, a full spectrum of pathologic conditions that afflict the bladder and urothelium are described and lavishly illustrated. With its emphasis on diagnostic criteria and differential diagnoses, this book is of particular value to practicing pathologists—assisting in the pathologist’s recognition, understanding, and accurate interpretation of the light microscopic findings in bladder specimens. Features and benefits of this new volume include: • 1,741 high-quality, color illustrations and 112 tables to illustrate the wide range of pathologic and clinical features in the urinary tract • An evidence-based approach to diagnosis and patient management for infectious, nonneoplastic, and neoplastic conditions • Recent advances in the molecular genetics of the urinary bladder with discussion of their current or potential impact on diagnosis and personalized patient care • With emphasis on the scientific validation of current diagnostic methods and their direct application in clinical practice, Bladder Pathology is a cutting-edge resource that not only offers comprehensive research and clinical information for practicing surgical pathologists, urologists, oncologists, and their clinical colleagues, but also captures a genuine sense of excitement about recent advances in this vital, ever-evolving field.

This book focuses on bladder cancer pathology, including primary bladder malignancies and other tumor varieties, with an emphasis on diagnostic pitfalls and clinical relevance. It also describes normal bladder histology, benign abnormalities with cancer mimickers, and cancer carcinogenesis, which are important subject matter for understanding bladder cancers, correct diagnosis, and differential diagnoses. Accurate diagnosis of bladder cancer plays a central role in daily pathology practice, clinical management, and prognosis. Advances in immunohistochemistry and molecular pathology have enhanced the accuracy of cancer pathology diagnoses. In addition to covering the anatomic and histologic features of bladder tumors, this book also reviews recent molecular and immunohistochemical advances in these areas. Recently updated clinical management information is also presented in this book. Written by experts in the field, Urinary Bladder Pathology serves as a useful resource for practicing pathologists, pathology trainees, and other health professionals who treat patients with bladder cancers.

Containing numerous illustrations and algorithms, this practical guide enlightens the diagnostic process for both common and complex bladder diseases.

This book focuses on bladder cancer pathology, including primary bladder malignancies and other tumor varieties, with an emphasis on diagnostic pitfalls and clinical relevance. It also describes normal bladder histology, benign abnormalities with cancer mimickers, and cancer carcinogenesis, which are important subject matter for understanding bladder cancers, correct diagnosis, and differential diagnoses. Accurate diagnosis of bladder cancer plays a central role in daily pathology practice, clinical management, and prognosis. Advances in immunohistochemistry and molecular pathology have enhanced the accuracy of cancer pathology diagnoses. In addition to covering the anatomic and histologic features of bladder tumors, this book also reviews recent molecular and immunohistochemical advances in these areas. Recently updated clinical management information is also presented in this book. Written by experts in the field, Urinary Bladder Pathology serves as a useful resource for practicing pathologists, pathology trainees, and other health professionals who treat patients with bladder cancers.

As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase