This book, written by experts from across the world, provides a comprehensive, up-to-date overview covering all aspects of posterior fossa neoplasms in pediatric patients, including medulloblastoma, ependymoma, cerebellar astrocytoma, atypical teratoid/rhabdoid tumor, chordoma, brain stem tumors, and rarer entities. For each tumor type, individual chapters are devoted to genetics, radiological evaluation using advanced imaging techniques, surgery, pathology, oncology, and radiation treatment. In addition, a separate section describes the various surgical approaches that may be adopted and offers guidance on the treatment of hydrocephalus and the role of intraoperative mapping and monitoring. Useful information is also provided on anatomy, clinical presentation, neurological evaluation, and molecular biology. The book closes by discussing in detail immediate postoperative care, the management of surgical complications, and longer-term rehabilitation and support. Posterior fossa tumors are the most common pediatric brain tumors but are often difficult to treat owing to their proximity to critical brain structures and their tendency to cause marked intracranial hypertension. Practitioners of all levels of experience will find Posterior Fossa Tumors in Children to be a richly illustrated, state of the art guide to the management of these tumors that will serve as an ideal reference in clinical practice.

It is estimated that the functionally significant body of knowledge for a given medical specialty changes radically every 8 years. New specialties and "sub-specialization" are occurring at approximately an equal rate. Historically, established journals have not been able either to absorb this increase in publishable material or to extend their readership to the new specialists. International and national meetings, symposia and seminars, workshops, and newsletters suc cessfully bring to the attention of physicians within developing spe cialties what is occurring, but generally only in demonstration form without providing historical perspective, pathoanatomical corre lates, or extensive discussion. Page and time limitations oblige the authors to present only the essence of their material. Pediatric neurosurgery is an example of a specialty that has de veloped during the past 15 years. Over this period neurosurgeons have obtained special training in pediatric neurosurgery and then dedicated themselves primarily to its practice. Centers, Chairs, and educational programs have been established as groups of neuro in different countries throughout the world organized surgeons themselves respectively into national and international societies for pediatric neurosurgery. These events were both preceded and fol lowed by specialized courses, national and international journals, and ever-increasing clinical and investigative studies into all aspects of surgically treatable diseases of the child's nervous system.

This book is a comprehensive and up-to-date compendium of all aspects of brain tumors in children. After introductory chapters on the epidemiology of brain tumors, the book will provide readers with state-of-the art chapters on the principals of radiation therapy, neurosurgery and neuroimaging. Subsequent chapters discuss the biology and treatment of specific types of brain tumors. The concluding chapters present critical information relevant to survivorship, neurocognitive and other late effects, and the global challenges to better diagnosis and treatment of brain tumors in children. This book is co-authored by experts in the treatment of pediatric brain tumors. All of the authors are internationally recognized authorities and they offer an evidence-based consensus on the biology and treatment of brain tumors. This handbook has far-reaching applicability to the clinical diagnosis and management of brain tumors in children and will prove valuable to specialists, generalists and trainees alike.

A practical guide to best practice in managing the perioperative care of pediatric neurosurgical patients.

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Adult neuropsychiatry is now a well-established field with numerous reputable references. Practitioners who work with children routinely note how references and practitioners knowledgeable in the equivalent work in the pediatric world are rare. Child psychiatrists and neurologists frequently work with individuals struggling with these conditions and would strongly benefit from such a reference that incorporates medical work-up, psychopharmacological recommendations, family/support recommendations and theoretical pathophysiology. Pediatricians and developmental pediatricians often treat children with behavioral and neuropsychiatric sequelae, but are not well-trained in the neuropsychiatric management of these cases. Neuropsychologists and educational psychologists working with children and adults with pediatric-onset conditions will also find the text helpful to contextualize their cases, better-understand the medical evaluation and management and perhaps adjust recommendations that would supplement their own testing methods. Finally, sub-specialists in adult neurology, psychiatry and neuropsychiatry often find themselves working with these children by default as there are few pediatric subspecialists who are available to accept them into practice. When facing complex neuropsychiatric illness in children, many clinicians are stymied because they may have “never seen a case like that”. This text fills the wide gap that currently exists and helps move this field forward. The approach utilized in adult neuropsychiatry that is both clear and accessible does not yet have an equivalent in the pediatric realm, but there is tremendous interest in its development. Children and adolescents with neuropsychiatric conditions are very common and they and their caregivers often struggle to find professionals well educated in this field. Ultimately, a wide range of clinicians will find this text to be a very helpful resource for diagnosis and management in the spectrum of pediatric neuropsychiatric conditions. The case-based approach is also unique with respect to neuropsychiatric approaches, and the clear cut, reader-friendly approach of such a format would likely be well-received among physicians looking for a resource on this issue.

The authors present the most current and cutting-edge knowledge regarding the molecular basis of cerebellar development, focusing on information relevant to laboratory scientists and clinicians providing service to patients with cerebellar disorders. Knowledge obtained from advanced neuroimaging techniques that are used during development, and from molecular- and genetic-based studies has provided rapidly-growing evidence that the cerebellum is a brain region that is highly impacted by developmental defects. Cerebellar defects result in significant intellectual and motor function impairment that affects both the patients and their families.