This book is designed to introduce the reader to the field of NMR/MRI at very low magnetic fields, from milli-Tesla to micro-Tesla, the ultra-low field (ULF) regime. The book is focused on applications to imaging the human brain, and hardware methods primarily based upon pre-polarization methods and SQUID-based detection. The goal of the text is to provide insight and tools for the reader to better understand what applications are best served by ULF NMR/MRI approaches. A discussion of the hardware challenges, such as shielding, operation of SQUID sensors in a dynamic field environment, and pulsed magnetic field generation are presented. One goal of the text is to provide the reader a framework of understanding the approaches to estimation and mitigation of low signal-to-noise and long imaging time, which are the main challenges. Special attention is paid to the combination of MEG and ULF MRI, and the benefits and challenges presented by trying to accomplish both with the same hardware. The book discusses the origin of unique relaxation contrast at ULF, and special considerations for image artifacts and how to correct them (i.e. concomitant gradients, ghost artifacts). A general discussion of MRI, with special consideration to the challenges of imaging at ULF and unique opportunities in pulse sequences, is presented. The book also presents an overview of some of the primary applications of ULF NMR/MRI being pursued.

The World Health Organization stated that approximately two-thirds of the world’s population lacks adequate access to medical imaging. The scarcity of imaging services in developing regions contributes to a widening disparity of health care and limits global public health programs that require imaging. Radiology is an important component of many global health programs, including those that address tuberculosis, AIDS-related disease, trauma, occupational and environmental exposures, breast cancer screening, and maternal-infant health care. There is a growing need for medical imaging in global health efforts and humanitarian outreach, particularly as an increasing number of academic, government, and non-governmental organizations expand delivery of health care to disadvantaged people worldwide. To systematically deploy clinical imaging services to low-resource settings requires contributions from a variety of disciplines such as clinical radiology, epidemiology, public health, finance, radiation physics, information technology, engineering, and others. This book will review critical concepts for those interested in managing, establishing, or participating in a medical imaging program for resource-limited environments and diverse cross-cultural contexts undergoing imaging technology adaptation.

Quantitative Magnetic Resonance Imaging is a 'go-to' reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: - The basic physics behind tissue property mapping - How to implement basic pulse sequences for the quantitative measurement of tissue properties - The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* - The pros and cons for different approaches to mapping perfusion - The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor - maps and more complex representations of diffusion - How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed - How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance - Fingerprinting can be used to accelerate or improve tissue property mapping schemes - How tissue property mapping is used clinically in different organs - Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds - Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements - Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges - Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches

In the past few decades, Magnetic Resonance Imaging (MRI) has become an indispensable tool in modern medicine, with MRI systems now available at every major hospital in the developed world. But for all its utility and prevalence, it is much less commonly understood and less readily explained than other common medical imaging techniques. Unlike optical, ultrasonic, X-ray (including CT), and nuclear medicine-based imaging, MRI does not rely primarily on simple transmission and/or reflection of energy, and the highest achievable resolution in MRI is orders of magnitude smaller that the smallest wavelength involved. In this book, MRI will be explained with emphasis on the magnetic fields required, their generation, their concomitant electric fields, the various interactions of all these fields with the subject being imaged, and the implications of these interactions to image quality and patient safety. Classical electromagnetics will be used to describe aspects from the fundamental phenomenon of nuclear precession through signal detection and MRI safety. Simple explanations and Illustrations combined with pertinent equations are designed to help the reader rapidly gain a fundamental understanding and an appreciation of this technology as it is used today, as well as ongoing advances that will increase its value in the future. Numerous references are included to facilitate further study with an emphasis on areas most directly related to electromagnetics.

Equine MRI is a unique, comprehensive guide to MRI in the horse. Edited by Rachel Murray, a leading authority and researcher in the field with over ten years of equine clinical MRI experience, the book also includes contributions from worldwide experts in the subject. Divided into the following four sections, the book presents key information based on previous validation work and clinical practice: Principles of MRI, including the practicalities of image acquisition and interpretation Normal MRI anatomy and normal variations Different types of pathological change Options for clinical management and prognosis for different conditions MRI is a rapidly expanding area in veterinary medicine that confers detailed, three-dimensional information on both bone and soft tissue. Expanding clinical knowledge, improvements in technology, and practical application of MRI to the standing and recumbent horse means this useful imaging modality has become an integral and essential part of the diagnostic evaluation in lameness and is a realistic option for investigation of ophthalmological, neurological and cranial pathology. Equine MRI enables readers to understand the best ways to achieve good quality images, and provides a detailed explanation of the problems that may occur. With close to 950 normal and abnormal images, this book offers considerable detail and examples of both common and uncommon problems, making it a great reference for equine veterinarians, veterinary students, specialists in equine surgery, and specialists in veterinary imaging.

In recent years, there has been increasing interest in the clinical applications of coronary angiography techniques. Coronary MRA can be instrumental in the evaluation of congenital coronary artery anomalies, however, the complexity of advanced MR pulse sequences and strategies may be overwhelming to many. Coronary MR Angiography demystifies the art of coronary MRA by providing a text in plain language with clearly illustrated imaging steps and protocols. Designed to bridge the gap between radiology and cardiology, it is written for physicians and scientists planning to incorporate this technique into their research or practice.