Outlines recent advances in the field of polar organometallic chemistry, particularly in the context of the emergent areas of synergic and cooperative species. Polar Organometallic Reagents provides a critical overview of developments in the field of modern polar organometallic chemistry. With a particular focus on the emergent area of synergic heterometallic reagents, this timely volume describes our attempts to understand recently developed polar organometallics and their application in a range of new directions. Contributions from leading researchers present new synthetic work and discuss recent advances in characterization techniques, synthetic applications, and mechanistic understanding of heterometallic complexes. In-depth chapters provide detailed information on fundamental, structural, and theoretical aspects of polar organometallic chemistry while articulating the need and rationale for the advent of new reagents. Topics include alkali and alkaline earth organometallics, synergy and cooperativity, cationic p-block clusters and other developments in main group catalysis, synthetic trends in alkenyl copper, ate complex and borylmetal chemistry, non-traditional reaction environments, and trends in developing greener processes. Designed to keep readers updated with the latest progress in the field, this much-needed book: Includes an introductory chapter outlining the development of synergic bases and the logic behind their creation Highlights the role of solid-state structural work in elucidating the bonding and reactivity displayed by modern polar organometallics Examines the use of calculations in catalyst design and plotting more sustainable reaction pathways Discusses modern trends in solution techniques that have achieved new insights into the structures of active species Presents striking advances in the ease of handling of polar organometallics and the emergence of main group catalysis Polar Organometallic Reagents is essential reading for researchers in chemical disciplines including synthetic inorganic and coordination chemistry, main group chemistry, organometallic chemistry, organic synthesis and catalysis.

Polar organometallic compounds are indispensable for the synthetic chemist. As this book shows, these almost ideal reagents are easy to prepare with high specificity under mild conditions and yet react quite readily with a great variety of substrates. Many compounds can be metallated directly at positions which would otherwise be difficult to substitute. Functional groups and heteroatoms already present in a molecule direct metallation to sites in their vicinity. The rules which govern polar organometallic chemistry often are not dominated by the usual n-delocalization and inductive effects; dipolar interactions, chelation, polarization, etc. often can be much more important. This affords novel synthetic opportunities. A good example is the development of a basically new type of aromatic substitution chemistry not based on positively charged intermediates. Seebach's injunction, "Thinking of polar organometallic compounds as carbanions is an impoverishment rather than a simplification" (International Symposium, Chemistry of Carbanions, Durham 1984), stresses the need to consider the metal not only as an integral, but perhaps also as the key component of these reagents. Rather than wandering off as solvated cations and acting as uninvolved spectators, the metals, rather than the anion moieties, can initiate and govern the subsequent reactions. To the founders of this field, e. g. Grignard, Ziegler, Gilman, Wittig, and their followers, the metal was critical. The title of Schlosser's book, "Polare Organometalle", certainly was apt.

This book provides the reader with a comprehensive introduction to the topic of organometallic chemistry. With an easy to follow structure covering both non-transition metals and transition metals as well as the applications of organometallic reagents in organic synthesis, this book is a must-have for the organometallic chemist. Thematic overview of organometallic compounds of transition and non-transition metals. Covers structures as well as applications.

The second edition of Comprehensive Organic Synthesis—winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers—builds upon the highly respected first edition in drawing together the new common themes that underlie the many disparate areas of organic chemistry. These themes support effective and efficient synthetic strategies, thus providing a comprehensive overview of this important discipline. Fully revised and updated, this new set forms an essential reference work for all those seeking information on the solution of synthetic problems, whether they are experienced practitioners or chemists whose major interests lie outside organic synthesis. In addition, synthetic chemists requiring the essential facts in new areas, as well as students completely new to the field, will find Comprehensive Organic Synthesis, Second Edition, Nine Volume Set an invaluable source, providing an authoritative overview of core concepts. Winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers Contains more than170 articles across nine volumes, including detailed analysis of core topics such as bonds, oxidation, and reduction Includes more than10,000 schemes and images Fully revised and updated; important growth areas—including combinatorial chemistry, new technological, industrial, and green chemistry developments—are covered extensively

Containing chemical, physical and structural data on 45,000 organometallics, this new edition of Dictionary of Organometallic Compounds is completely reviews and expanded. All compounds from the first edition have been reviewed, new references from the recent chemical literature have been added. Interesting new compounds, which have appeared in the literature from 1985 to 1993, have also been incorporated. A unique new feature is the Index of Synthetic Reagents, which groups compounds according to their use in synthetic organic chemistry. Compounds included: - organometallics representing all important structural types - compounds with an established use, such as orignard reagents, catalysts, starting materials, laboratory chemicals Type of information included: - accurate systematic chemical names, tradenames, trivial names - CAS Registry numbers - molecular formulae and weights - details on synthesis/preparation - uses in synthetic organic chemistry - physical data including melting/boiling points, solubility, magnetic susceptibility - concise bibliography

A succinct review of the essential concepts of organometallic chemistry, enriched throughout with examples that demonstrate how our understanding of organometallic chemistry has led to new applications in research and industry - not least in relation to catalysis.

WINNER of the 2013 PROSE Award in Chemistry & Physics This latest edition enables readers to master new classes of organometallic compounds and syntheses A popular resource used by synthetic organic chemists around the world, this book enables readers to conduct seamless synthetic reactions involving key organometallics. Each reaction is set forth in the book's acclaimed recipe-style format so that readers can easily replicate the results in their own labs. Moreover, each chapter has been written by a world leader in the field of organometallics in organic synthesis. These authors offer hands-on guidance and practical examples illustrating the preparation of organometallics and its application in organic synthesis. This Third Manual of Organometallics in Synthesis features completely new content and topics, with an eye towards providing researchers with the most useful and practical reference on the synthesis of organometallics. Organized into chapters by type of organometallic compound, the book covers: Organoalkali chemistry Organomagnesium and organozinc chemistry Organosilicon and relating organotin chemistry Organoiron chemistry Organopalladium chemistry Within each chapter, readers will find background information to learn more about the class of organometallics as well as mechanistic considerations. The authors thoroughly discuss the various methods of preparing the organometallic compounds presented in the book and outline their uses in synthetic reactions. In addition to current applications, the authors explore future research opportunities for each organometallic class. References at the end of each chapter enable readers to explore all the topics in greater depth. More and more industrial processes rely on organometallic chemistry. As a result, readers will find this book's step-by-step instructions essential in such fields as natural product synthesis, pharmaceuticals, fine chemicals, biotechnology, polymers, and materials science.