Disorders of menstruation are among the most common problems encountered in womens' health and include early, delayed and irregular menstrual cycles, painful menses and excessive menstrual bleeding, and early menopause. Their treatment presents a variety of complex challenges, especially since some of the treatments used can themselves result in fu

When John F. Kennedy was shot, millions were left to wonder how America, and the world, would have been different had he lived to fulfill the enormous promise of his presidency. For many historians and political observers, what Kennedy would and would not have done in Vietnam has been a source of enduring controversy. Now, based on convincing new evidence--including a startling revelation about the Kennedy administration's involvement in the assassination of Premier Diem--Howard Jones argues that Kennedy intended to withdraw the great bulk of American soldiers and pursue a diplomatic solution to the crisis in Vietnam. Drawing upon recently declassified hearings by the Church Committee on the U.S. role in assassinations, newly released tapes of Kennedy White House discussions, and interviews with John Kenneth Galbraith, Robert McNamara, Dean Rusk, and others from the president's inner circle, Jones shows that Kennedy firmly believed that the outcome of the war depended on the South Vietnamese. In the spring of 1962, he instructed Secretary of Defense McNamara to draft a withdrawal plan aimed at having all special military forces home by the end of 1965. The "Comprehensive Plan for South Vietnam" was ready for approval in early May 1963, but then the Buddhist revolt erupted and postponed the program. Convinced that the war was not winnable under Diem's leadership, President Kennedy made his most critical mistake--promoting a coup as a means for facilitating a U.S. withdrawal. In the cruelest of ironies, the coup resulted in Diem's death followed by a state of turmoil in Vietnam that further obstructed disengagement. Still, these events only confirmed Kennedy's view about South Vietnam's inability to win the war and therefore did not lessen his resolve to reduce the U.S. commitment. By the end of November, however, the president was dead and Lyndon Johnson began his campaign of escalation. Jones argues forcefully that if Kennedy had not been assassinated, his withdrawal plan would have spared the lives of 58,000 Americans and countless Vietnamese. Written with vivid immediacy, supported with authoritative research, Death of a Generation answers one of the most profoundly important questions left hanging in the aftermath of John F. Kennedy's death. Death of a Generation was a CHOICE Outstanding Academic Title for 2003.

Medical and Health Genomics provides concise and evidence-based technical and practical information on the applied and translational aspects of genome sciences and the technologies related to non-clinical medicine and public health. Coverage is based on evolving paradigms of genomic medicine—in particular, the relation to public and population health genomics now being rapidly incorporated in health management and administration, with further implications for clinical population and disease management. - Provides extensive coverage of the emergent field of health genomics and its huge relevance to healthcare management - Presents user-friendly language accompanied by explanatory diagrams, figures, and many references for further study - Covers the applied, but non-clinical, sciences across disease discovery, genetic analysis, genetic screening, and prevention and management - Details the impact of clinical genomics across a diverse array of public and community health issues, and within a variety of global healthcare systems

VOLUME 1: INFERTILITY SECTION 1: ANATOMY AND PHYSIOLOGY 1. Anatomy of the Reproductive System 2. Regulation and Physiology of Menstrual Cycle 3. Oogenesis and Folliculogenesis 4. Spermatogenesis 5. Fertilization and Embryogenesis 6. Implantation 7. Embryo Endometrial Crosstalk and Endometrial Receptivity SECTION 2: REPRODUCTIVE ENDOCRINOLOGY 8. Synthesis and Metabolism of Steroid Hormones 9. Puberty and Aberrations 10. Amenorrhea 11. Endocrine Disorders Affecting Reproduction 12. Hirsutism 13. Luteal Phase Defect 14. Anovulation 15. Declining Fertility SECTION 3: COMBINED TOPICS 16. Evaluation of Infertility 17. Immunology and Infertility 18. Cytogenetics and Subfertility 19. Obesity and Infertility 20. Unexplained Infertility 21. Fertility Preservation 22. Counseling in Infertility 23. Assisted Reproductive Technology in Patients with Chronic Medical Disorders SECTION 4: MALE INFERTILITY 24. Etiopathogenesis of Male Infertility 25. Clinical and Endocrinological Evaluation of Infertile Male 26. Sexual Dysfunction in Male Infertility 27. Ultrasound in Male Infertility 28. Medical Management of Male Infertility 29. Azoospermia: Evaluation and Management 30. Varicocele and Infertility 31. Spinal Cord Injuries and Male Infertility 32. Algorithms for Genetic Evaluation of Infertile Males SECTION 5: FEMALE FACTOR INFERTILITY 33. Uterine Factors in Infertility 34. Tubal Factors in Infertility 35. Infections and Infertility 36. Tuberculosis and Infertility 37. Sonoendocrinology and Cycle Monitoring Assisted Reproduction Technology 38. Transvaginal Ultrasound and Doppler in Infertility 39. Polycystic Ovary Syndrome 40. Assessment of Ovarian Reserve 41. Endometriosis 42. Endoscopy in Infertility 43. Reconstructive Surgeries Enhancing Fertility SECTION 6: INTRAUTERINE INSEMINATION 44. Intrauterine Insemination 45. Optimizing Success in Intrauterine Insemination SECTION 7: OVARIAN STIMULATION 46. Drugs for Ovarian Stimulation 47. Ovulation Induction and Ovarian Stimulation Protocols 48. Role of Adjuvants in Ovarian Stimulation 49. Gonadotropinreleasing Hormone Analogs 50. Monitoring of Ovarian Stimulation 51. Ovulation Trigger 52. Individualized Controlled Ovarian Stimulation 53. In Vitro Fertilization Lite 54. Role of Luteinizing Hormone in Ovarian Stimulation 55. Anesthesia in Assisted Reproductive Techniques 56. Oocyte Retrieval. 57. Embryo Transfer 58. Troubleshooting in Assisted Reproductive Technology 59. Luteal Phase Support SECTION 8: DILEMMA IN ART 60. Poor Responder 61. Recurrent Implantation Failure 62. Empty Follicle Syndrome 63. Role of Aneuploidy Screening in Preimplantation Embryos 64. Preimplantation Genetic Testing of Embryos 65. Epigenetics and Assisted Reproductive Technology SECTION 9: COMPLICATIONS IN ART 66. Ovarian Hyperstimulation Syndrome 67. Ectopic Pregnancy 68. Multipleorder Births SECTION 10: THIRD PARTY REPRODUCTION 69. Oocyte and Sperm Donation 70. Surrogacy in Assisted Reproductive Technology 71. Assisted Reproductive Technology Guidelines 72. Adoption 73. LGBTQ and Fertility 74. Transgender Population and Fertility SECTION 11: OUTCOME FOLLOWING ASSISTED REPRODUCTIVE TECHNIQUE 75. Maternal and Fetal Outcomes Following Assisted Reproductive Technique 76. Early Pregnancy Scan 77. Recurrent Pregnancy Loss: From Diagnostic Dilemmas to Clinical Decisions SECTION 12: RECENT ADVANCES 78. Bioengineered Human Endometrium In Vitro. 79. Recent Trends in A...

Presenting the most current and relevant information on the diagnosis and management of primary ovarian insufficiency, also known as premature ovarian failure (POI/POF), this book presents two equally important voices. The first is the scientific, evidence-based voice discussing the latest information on POI/POF in a concise and logical fashion: etiologies, symptoms, genetics, mechanisms, associated conditions, as well as psychological and lifestyle considerations. The second voice presents the first-person stories of affected women, who are often faced with a diagnosis of irreversible infertility at a very young age and who somehow learn to live with great uncertainty about their ability to create a family – a core identity issue for many women. It is thus not simply a clinical, case-based presentation, but a more collaborative effort between clinicians who are well-versed in the field and women who have POI/POF. Primary Ovarian Insufficiency: A Clinical Guide to Early Menopause will therefore be an excellent practical yet personal reference for OB/GYNs, reproductive medicine specialists, and any clinician, nurse or health care worker treating women living with POI/POF.