The author utilizes metaphor, simile and the occasional reference to make one ponder and self-reflect. Through the use of streams of conscious, he encourages self-hypnosis or creative visualization that allows us to imagine our capabilities or to see our possibilities before making changes in our lives. Stressing the importance of remaining child-like when appropriate, allowing whimsey and daydreaming to stay an active exercise in our lives, the author stresses the importance of seeing what we are looking at, like a visual artist, but with word usage. A repeated theme places us on a cruise ship, staring out to where the sea meets the sky. By allowing ourselves to look outside of ourselves, we try to find meaning in our lives. Another repeated theme is that of defining or characterizing entities in ways to establish order and place expectations so that we conform or behave in ways as others would expect us to perform or behave. The author would encourage us to challenge such defining and characterizations, in order to develop a stronger sense of who we are. Bonus writings relating to changes imposed upon us by Covid and other World events, should seem meaningful to all of us, and likely in very different ways. Do you think we have learned anything from our Covid experiences? Would the author’s use of metaphor improve how we see ourselves, and our places in other people's lives? Spotting a sea serpent along the voyage would add even more self-awareness and insight.

Presenting both a panoramic introduction to the essential disciplines of drug discovery for novice medicinal chemists as well as a useful reference for veteran drug hunters, this book summarizes the state-of-the-art of medicinal chemistry. It covers key drug targets including enzymes, receptors, and ion channels, and hit and lead discovery. The book hen surveys a drug's pharmacokinetics and toxicity, with a solid chapter covering fundamental bioisosteres as a guide to structure-activity relationship investigations.