A bold new plan for those concerned about rising temperatures, population projections, and spreading water scarcity.

Medical Eligibility Criteria for Contraceptive Use reviews the medical eligibility criteria for use of contraception, offering guidance on the safety and use of different methods for women and men with specific characteristics or known medical conditions. The recommendations are based on systematic reviews of available clinical and epidemiological research. It is a companion guideline to Selected Practice Recommendations for Contraceptive Use. Together, these documents are intended to be used by policy-makers, program managers, and the scientific community to support national programs in the preparation of service delivery guidelines. The fourth edition of this useful resource supersedes previous editions, and has been fully updated and expanded. It includes over 86 new recommendations and 165 updates to recommendations in the previous edition. Guidance for populations with special needs is now provided, and a new annex details evidence on drug interactions from concomitant use of antiretroviral therapies and hormonal contraceptives. To assist users familiar with the third edition, new and updated recommendations are highlighted. Everyone involved in providing family planning services and contraception should have the fourth edition of Medical Eligibility Criteria for Contraceptive Use at hand.

Provides alternative solutions to such global problems as population control, emerging water shortages, eroding soil, and global warming, outlining a detailed survival strategy for the civilization of the future.

You have a new venture in mind. And you've crafted a business plan so detailed it's a work of art. Don't get too attached to it. As John Mullins and Randy Komisar explain in Getting to Plan B, new businesses are fraught with uncertainty. To succeed, you must change the plan in real time as the inevitable challenges arise. In fact, studies show that entrepreneurs who stick slavishly to their Plan A stand a greater chance of failing-and that many successful businesses barely resemble their founders' original idea. The authors provide a rigorous process for stress testing your Plan A and determining how to alter it so your business makes money, solves customers' needs, and endures. You'll discover strategies for: -Identifying the leap-of-faith assumptions hidden in your plan -Testing those assumptions and unearthing why the plan might not work -Reconfiguring the five components of your business model-revenue model, gross margin model, operating model, working capital model, and investment model-to create a sounder Plan B. Filled with success stories and cautionary tales, this book offers real cases illustrating the authors' unique process. Whether your idea is for a start-up or a new business unit within your organization, Getting to Plan B contains the road map you need to reach success.

Provides alternative solutions to such global problems as population control, emerging water shortages, eroding soil, and global warming, outlining a detailed survival strategy for the civilization of the future.

#1 NEW YORK TIMES BESTSELLER • A gripping new Jack Reacher thriller from Lee Child and Andrew Child “No Plan B is not to be missed. A perfectly plotted, fast-paced thriller, with bigger twists than ever before. It’s no wonder Jack Reacher is everyone’s favorite rebel hero.”—Karin Slaughter ONE OF THE BEST BOOKS OF THE YEAR: Reader’s Digest In Gerrardsville, Colorado, a woman dies under the wheels of a moving bus. The death is ruled a suicide. But Jack Reacher saw what really happened: A man in a gray hoodie and jeans, moving stealthily, pushed the victim to her demise—before swiftly grabbing the dead woman’s purse and strolling away. When another homicide is ruled an accident, Reacher knows this is no coincidence. With a killer on the loose, Reacher has no time to waste to track down those responsible. But Reacher is unaware that these crimes are part of something much larger and more far-reaching: an arsonist out for revenge, a foster kid on the run, a cabal of powerful people involved in a secret conspiracy with many moving parts. There is no room for error, but they make a grave one. They don’t consider Reacher a threat. “There’s too much at stake to start running from shadows.” But Reacher isn’t a shadow. He is flesh and blood. And relentless when it comes to making things right. For when the threat is Reacher, there is No Plan B.

Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.