Annotation - infectious diseases- non-infectious diseases- bioterrorism.

Covering some of humankind's most notorious diseases, this book describes, with individual examples, the changing historical relationships between humans and their diseases, many of which they have helped to create. Contemporary illustrations show how the diseases were perceived in the past.

Since publication of the initial version of Plagues & Poxes in 1987, which had the optimistic subtitle "The Rise and Fall of Epidemic Disease," the rise of new diseases such as AIDS and the deliberate modification and weaponization of diseases such as anthrax have changed the way we perceive infectious disease. With major modifications to deal with this new reality, the acclaimed author of Civil War Medicine: Challenges and Triumphs has updated and revised this series of essays about changing disease patterns in history and some of the key events and people involved in them. It deals with the history of major outbreaks of disease - both infectious diseases such as plague and smallpox and noninfectious diseases - and shows how they are in many cases caused inadvertently by human actions, including warfare, commercial travel, social adaptations, and dietary modifications. To these must now be added discussion of the intentional spreading of disease by acts of bioterrorism, and the history and knowledge of those diseases that are thought to be potential candidates for intentional spread by bioterrorists. Among the many topics discussed are: How the spread of smallpox and measles among previously unexposed populations in the Americas, the introduction of malaria and yellow fever from Africa via the importation of slaves into the Western hemisphere, and the importation of syphilis to Europe all are related to the modern interchange of diseases such as AIDS. How the ever-larger populations in the cities of Europe and North America gave rise to "crowd diseases" such as polio by permitting the existence of sufficient numbers of non-immune people in sufficient numbers to keep the diseases from dying out. How the domestication of animals allowed diseases of animals to affect humans, or perhaps become genetically modified to become epidemic human diseases. Why the concept of deficiency diseases was not understood before the early twentieth century; disease, after all, was the presence of something abnormal, how could it be due to the absence of something? In fact, the first epidemic disease in human history probably was iron deficiency anemia. How changes in the availability and nature of specific foods have affected the size of population groups and their health throughout history. The introduction of potatoes to Ireland and corn to Europe, and the relationship between the modern technique of rice milling and beriberi, all illustrate the fragile nutritional state that results when any single vegetable crop is the main source of food. Why biological warfare is not a new phenomenon. There have been attempts to intentionally cause epidemic disease almost since the dawn of recorded history, including the contamination of wells and other water sources of armies and civilian populations; of course, the spread of smallpox to Native Americans during the French and Indian War is known to every schoolchild. With our increased technology, it is not surprising that we now have to deal with problems such as weaponized spores of anthrax.

A horrifying epidemic of smallpox was sweeping across the Americas when the War of Independence began, and yet little is known about it. Fenn reveals how deeply "variola" affected the outcome of the war in every colony and the lives of everyone in North America. Illustrations.

A century and a half after the Black Death killed over a third of the population of Western Europe, a new plague swept across the continent. The Great Pox - commonly known as the French Disease - brought a different kind of horror: instead of killing its victims rapidly, it endured in their bodies for years, causing acute pain, disfigurement and ultimately an agonising death. The authors analyse the symptoms of the Great Pox and the identity of patients, richly documented in the records of the massive hospital of 'incurables' established in early sixteenth-century Rome. They show how the disease threw accepted medical theory and practice into confusion and provoked public disputations among university teachers. And at the most practical level they reveal the plight of its victims at all levels of society, from ecclesiastical lords to the poor who begged in the streets. Examining a range of contexts from princely courts and republics to university faculties, confraternities and hospitals, the authors argue powerfully for a historical understanding of the Great Pox based on contemporary perceptions rather than on a retrospective diagnosis of what later generations came to know as 'syphilis'.

Whatever programs you develop, there's one task that you will almost always have to achieve - accessing and manipulating data. This data can be stored in many places, but large quantities of data that need to be frequently accessed are usually stored in relational databases such as SQL Server. Knowing how this data is structured, and how to access and update it, is therefore one of the most important programming tasks the professional programmer needs to learn. This book is designed to teach those essential skills quickly and painlessly to anyone programming in Microsoft's new C SHARP language. As well as database basics such as the SQL language used to communicate with databases, we cover the specifics of data access using C SHARP in depth. Data access in .NET is achieved through the ADO.NET classes; these are essentially a replacement for ActiveX Data Objects (ADO), and combine ADO's ease of use with powerful new features such as enhanced XML support. The core of this book consists of a thorough but easy-to-read tutorial to ADO.NET.

This fascinating new volume comes complete with color illustrations and features the methodology and main achievements in the emerging field of paleomicrobiology. It’s an area research at the intersection of microbiology and evolution, history and anthropology. New molecular approaches have already provided exciting results, such as confirmation of a single biotype of Yersinia pestis as the cause of historical plague pandemics. An absorbing read for scientists in related fields.