The International Symposium on Ruminant Physiology (ISRP) is the premier forum for presentation and discussion of advances in knowledge of the physiology of ruminant animals. This book brings together edited versions of the keynote review papers presented at the symposium.

This volume is comprised of invited papers presented at the Seventh International Symposium on Ruminant Physiology, held in Sendai, Japan, in September 1989. Papers are invited on the recommendations of 300 international experts. The proceedings of this symposia provides the most comprehensive coverage available of current research in ruminant physiology.

Russian physiologist and Nobel Prize winner Ivan Pavlov is most famous for his development of the concept of the conditional reflex and the classic experiment in which he trained a dog to salivate at the sound of a bell. In Pavlov's Physiology Factory: Experiment, Interpretation, Laboratory Enterprise, Daniel P. Todes explores Pavlov's early work in digestive physiology through the structures and practices of his landmark laboratory—the physiology department of the Imperial Institute for Experimental Medicine. In Lectures on the Work of the Main Digestive Glands, for which Pavlov won the Nobel Prize in 1904, the scientist frequently referred to the experiments of his coworkers and stated that his conclusions reflected "the deed of the entire laboratory." This novel claim caused the prize committee some consternation. Was he alone deserving of the prize? Examining the fascinating content of Pavlov's scientific notes and correspondence, unpublished memoirs, and laboratory publications, Pavlov's Physiology Factory explores the importance of Pavlov's directorship of what the author calls a "physiology factory" and illuminates its relationship to Pavlov's Nobel Prize-winning work and the research on conditional reflexes that followed it. Todes looks at Pavlov's performance in his various roles as laboratory manager, experimentalist, entrepreneur, and scientific visionary. He discusses changes wrought by government and commercial interests in science and sheds light on the pathways of scientific development in Russia—making clear Pavlov's personal achievements while also examining his style of laboratory management. Pavlov's Physiology Factory thus addresses issues of importance to historians of science and scientists today: "big" versus "small" science, the dynamics of experiment and interpretation, and the development of research cultures.

Two questions could not be avoided in the avant-propos of this book; (i) what is the importance to man of ruminant livestock, and (ii) what results of practical relevance in the growing mountain of scientific verbiage could be found in the Proceedings of this Symposium. Herbivores are an integral and critical part of the natural ecosystem which must be preserved because of their impact on human welfare. Wh at makes ruminants especially important to man is that they can thrive on fibrous forage and are thus the only viable enterprise over much of the earth's surface where crop growing is impracti cable. They contribute a wide array of products in addition to 50000 000 tonnes ofmeat (1977) and represent a 'capital reserve' that can be drawn upon in times of emergency: milk for example (450000000 tonnes) can make the difference between subsistence and starvation. About 60% of the world's meat and 80 % of the milk are produced by one third of the world ruminant population in the developed regions and as much as 99 % of the power for agriculture is provided by the ruminant population in developing countries. For the next two decades, a probable increase by 30 % for . cattle and buffalo and more than 40 % for sheep and goats is expected by improving health, fertility, nutrition and genetic potential rather than feed resources.

This book offers one of the most comprehensive reviews in the field of gastrointestinal (GI) physiology, guiding readers on a journey through the complete digestive tract, while also highlighting related organs and glandular systems. It is not solely limited to organ system physiology, and related disciplines like anatomy and histology, but also examines the molecular and cellular processes that keep the digestive system running. As such, the book provides extensive information on the molecular, cellular, tissue, organ, and system levels of functions in the GI system. Chapters on the roles of the gut as an endocrine, exocrine and neural organ, as well as its microbiome functions, broaden readers’ understanding of the multi-organ networks in the human body. To help illustrate the interconnections between the physiological concepts, principles and clinical presentations, it outlines clinical examples such as pathologies that link basic science with clinical practice in special “clinical correlates” sections. Covering both traditional and contemporary topics, it is a valuable resource for biomedical students, as well as healthcare and scientific professionals.