Physical Principles in Sensing and Signaling

Physical Principles in Sensing and Signaling
Title Physical Principles in Sensing and Signaling PDF eBook
Author Robert G. Endres
Publisher OUP Oxford
Pages 158
Release 2013-01-11
Genre Science
ISBN 0191654280

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Although invisible to the bare eye, bacterial cells are large enough to make complex decisions. Cells are composed of thousands of different molecular species including DNA, proteins, and smaller molecules, allowing them to sense their environment, to process this information, and to respond accordingly. Such responses include expression of genes or the control of their movement. Despite these properties, a living cell exists in the physical world and follows its laws. Keeping this in mind can help answer questions such as how cells work and why they implement solutions to problems the way they do. Applying physical principles in biology allows researchers to solve challenging problems at the interface between biology and the physical sciences, including how accurately biological cells can sense chemicals in their environment, how cells encode physical stimuli in biochemical pathways, or how cells amplify signals and adapt to persistent stimulation. In this book, the reader is introduced to this fascinating topic without the need for extensive mathematical details or huge prior knowledge in biological physics.

Physical Principles of Remote Sensing

Physical Principles of Remote Sensing
Title Physical Principles of Remote Sensing PDF eBook
Author Gareth Rees
Publisher Cambridge University Press
Pages 461
Release 2013
Genre Science
ISBN 110700473X

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A quantitative yet accessible introduction to remote sensing techniques, this new edition covers a broad spectrum of Earth science applications.

Handbook of Modern Sensors

Handbook of Modern Sensors
Title Handbook of Modern Sensors PDF eBook
Author Jacob Fraden
Publisher Springer Science & Business Media
Pages 671
Release 2010-09-22
Genre Technology & Engineering
ISBN 1441964665

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Since publication of the previous, the 3rd edition of this book, the sensor tech- logies have made a remarkable leap ahead. The sensitivity of the sensors became higher, the dimensions – smaller, the selectivity – better, and the prices – lower. What have not changed, are the fundamental principles of the sensor design. They still are governed by the laws of Nature. Arguably one of the greatest geniuses ever lived, Leonardo Da Vinci had his own peculiar way of praying. It went like this, “Oh Lord, thanks for Thou don’t violate Thy own laws. ” It is comforting indeed that the laws of Nature do not change with time, it is just that our appreciation of them becomes re?ned. Thus, this new edition examines the same good old laws of Nature that form the foundation for designs of various sensors. This has not changed much since the previous editions. Yet, the sections that describe practical designs are revised substantially. Recent ideas and developments have been added, while obsolete and less important designs were dropped. This book is about devices commonly called sensors. The invention of a microprocessor has brought highly sophisticated instruments into our everyday life. Numerous computerized appliances, of which microprocessors are integral parts, wash clothes and prepare coffee, play music, guard homes, and control room temperature. Sensors are essential components in any device that uses a digital signal processor.

Nanoscale Matter and Principles for Sensing and Labeling Applications

Nanoscale Matter and Principles for Sensing and Labeling Applications
Title Nanoscale Matter and Principles for Sensing and Labeling Applications PDF eBook
Author Dambarudhar Mohanta
Publisher Springer Nature
Pages 584
Release 2024
Genre Detectors
ISBN 9819978483

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Zusammenfassung: This book is a compilation of carefully chosen chapters that cover the subjects of nanoscale matter, sensing, and labelling applications. It is aimed primarily at scientists and researchers who are already involved in theme-based research or who are just starting their careers. Despite the diverse nature of the topics covered, which include a range of materials in various forms and uses, the emphasis is primarily on sensing and labelling phenomena. The book begins with materials quantification in nanoscale systems by using an innovative technique like "molecular secondary ion mass spectrometry without calibration standards". Subsequently, the book features an array of materials such as inorganic semiconductor nanoscale particles, carbon dots, rare-earth oxides, polymer nanocomposites, and a few biomaterials, all of which illustrate their functionality and potential for deployment in a wide variety of sensing applications. Although the book delves into the technical aspects of fabrication workouts to some extent, the focus is predominantly on the physical principles, mechanisms, and relevance involved in sensing and labelling applications. The book covers a wide range of topics that leverage the unique properties of nanoscale materials. By carefully selecting appropriate active materials, the authors explore the detection of LPG, hazardous and explosive gases, as well as humidity sensing and hydrogen evolution. It also delves into photo-sensing and persistent photoconductivity by using nanoscale semiconductors, which are used for heavy metal sensing and UV sensing, respectively. The use of metal nanoparticles in various forms is reviewed to address issues related to water contamination, biofilm protection, and food-borne pathogens. The book also discusses surface plasmon resonance, starting with its basic principles and expanding to its relevance in a broader perspective, with a greater focus on applied biosensing. Nanoscale ferrites and magnetic systems are explored with an emphasis on magnetic sensing and actuation. Lastly, the book explores the use of rare-earth-based nanosystems, highlighting persistent luminescence and up/down-converted transitions, which have unprecedented applications in bioimaging and biolabeling. Every effort has been made to strike a balance between the observed phenomena in the emerging areas of sensing applications and suitable theoretical treatments there in.

Systems Biology of Cell Signaling

Systems Biology of Cell Signaling
Title Systems Biology of Cell Signaling PDF eBook
Author James Ferrell
Publisher Garland Science
Pages 285
Release 2021-09-28
Genre Science
ISBN 1000430731

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How can we understand the complexity of genes, RNAs, and proteins and the associated regulatory networks? One approach is to look for recurring types of dynamical behavior. Mathematical models prove to be useful, especially models coming from theories of biochemical reactions such as ordinary differential equation models. Clever, careful experiments test these models and their basis in specific theories. This textbook aims to provide advanced students with the tools and insights needed to carry out studies of signal transduction drawing on modeling, theory, and experimentation. Early chapters summarize the basic building blocks of signaling systems: binding/dissociation, synthesis/destruction, and activation/inactivation. Subsequent chapters introduce various basic circuit devices: amplifiers, stabilizers, pulse generators, switches, stochastic spike generators, and oscillators. All chapters consistently use approaches and concepts from chemical kinetics and nonlinear dynamics, including rate-balance analysis, phase plane analysis, nullclines, linear stability analysis, stable nodes, saddles, unstable nodes, stable and unstable spirals, and bifurcations. This textbook seeks to provide quantitatively inclined biologists and biologically inclined physicists with the tools and insights needed to apply modeling and theory to interesting biological processes. Key Features: Full-color illustration program with diagrams to help illuminate the concepts Enables the reader to apply modeling and theory to the biological processes Further Reading for each chapter High-quality figures available for instructors to download

Handbook of Modern Sensors

Handbook of Modern Sensors
Title Handbook of Modern Sensors PDF eBook
Author Jacob Fraden
Publisher Springer Science & Business Media
Pages 596
Release 2004
Genre Science
ISBN 0387007504

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This book is about devices commonly called sensors. Digital systems, however complex and intelligent they might be, must receive information from the outside world that is generally analog and not electrical. Sensors are interface devices between various physical values and the electronic circuits who "understand" only a language of moving electrical charges. In other words, sensors are the eyes, ears, and noses of silicon chips. Unlike other books on sensors, this book is organized according to the measured variables (temperature, pressure, position, etc.) that make it much more practical and easier to read. In this new edition recent ideas and developments have been added while less important and non-essential designs were dropped. Sections on practical designs and use of the modern micro-machining technologies have been revised substantially. This book is a reference text that can be used by students, researchers interested in modern instrumentation (applied physicists and engineers), sensor designers, application engineers and technicians whose job it is to understand, select and/or design sensors for practical systems. The scope of this book is rather broad covering many different designs. Some are well known, but describing them is still useful for students and those who look for a convenient reference. It is the author's intention to present a comprehensive and up-to-date account of the theory (physical principles), design, and practical implementations of various sensors for scientific, industrial, and consumer applications.nbsp;nbsp;From the reviews:"... A very useful book ... It strikes an excellent balance between a large variety of different sensor types and moderate description of each to yield a book of reasonable length ... Provides excellent information on all types of physical measurements. I recommend it highly." Biomedical Instrumentation & Technology"Jacob Fraden has produced a valuable, single-volume reference on the devices that bridge the analog and digital worlds." Lawrence Rubin, MIT From the reviews of the third edition:"This is a weighty volume of nearly 600 pages. ... The book is undoubtedly useful as a source of reference. The large number of sensors described in it, and the consideration of underlying principles of operation should help people ... ." (Allan Hobson, Robotica, Vol. 23, 2005)"This book handles the basic and absolutely most important common areas of all sensor applications. It gives a good overview of a very wide range of sensor applications, which is not found in many other books in such a detailed form. ... This book is useful for everybody who works with any kind of measurement technique. For beginners it is a good introduction to the world of sensors. For advanced users it is a good and extensive handbook and help." (Rüdiger Frank, Analytical and Bioanalytical Chemistry, Vol. 382, 2005)"This book ... aims for breadth and to be a reasonably comprehensive account of most modern sensors. ... The Handbook is a readable reference text for researchers, graduate students and engineers ... . Don't read this book if you don't want to know how the sensors work ... . If, however you want to understand how a sensor works, the principle behind it ... or use all that sensors have to offer technically, then this book is for you." (Stephen Kukureka Fimmm, Materials World, Vol. 13 (2), February, 2005)

Introduction to Fluorescence Sensing

Introduction to Fluorescence Sensing
Title Introduction to Fluorescence Sensing PDF eBook
Author Alexander P. Demchenko
Publisher Springer
Pages 818
Release 2015-10-06
Genre Medical
ISBN 3319207806

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Fluorescence is the most popular technique in chemical and biological sensing and this book provides systematic knowledge of basic principles in the design of fluorescence sensing and imaging techniques together with critical analysis of recent developments. Its ultimate sensitivity, high temporal and spatial resolution and versatility enables high resolution imaging within living cells. It develops rapidly in the directions of constructing new molecular recognition units, new fluorescence reporters and in improving sensitivity of response, up to the detection of single molecules. Its application areas range from the control of industrial processes to environmental monitoring and clinical diagnostics. Being a guide for students and young researchers, it also addresses professionals involved in basic and applied research. Making a strong link between education, research and product development, this book discusses prospects for future progress.