In this book we attempt to summarize the present state of knowledge in the field of photoimmunology and to provide the background necessary to put this knowledge into perspective. This objective requires descriptive overviews in photobiology, immunology, and dermatology. Our hope is to facilitate interdis ciplinary communication and to stimulate interest in photoimmunology. Section I, Principles of Photoimmunology, describes (1) basic interactions between UV and visible radiation and biologic matter, (2) the optical properties of human skin, and (3) normal and abnormal responses to UV radiation. Basic principles of selected aspects of immunology and photobiology are explained. Section II, Experimental Photoimmunology, describes molecular, cellular, animal, and human studies in photoimmunology. Section III, Clinical Photo immunology, presents evidence of the involvement of photoimmunologic mechanisms in diseases of the skin and blood and examines the possible involve ment of immunologic mechanisms in therapeutic photomedicine. The funda mental principles outlined in this book should prove useful for decades to come. However, our expectation is that the experimental data will be outdated in a short period of time. The potential of photoimmunology is great enough and the serious study of photo immunology is recent enough that this should be the case. This book is dedicated to the goal of continuing rapid growth in the field of photoimmunology .

Dermatologists are being asked to understand the pathophysiology of a number of immune-mediated skin diseases. In addition, a number of new products have appeared on the market during the past decade which requires an understanding of the mechanisms of action of these drugs. Dermatologists, however, have no easily understood book to which they can refer to regarding the disease or the drug.

The skin immune response/photoallergy/photoimmunology of lupus/UV & infectious disease/therapeutic photoimmunology.

Photobiology integrates a wide variety of scientific disciplines. As more people become aware of the many ways light interacts with chemical and biological systems, the need for a concise treatment of photobiology has become more critical. Kohen et al. Have written just such a book, intended both as a textbook and as a reference.The authors begin by providing a brief description of the nature of light, how it affects matter, and the means and methods of measuring it. A major section of the book is devoted to how light influences living systems, including discussions of photosynthesis, bioluminescence, regulatory mechanisms, and visual transduction of light. The last half of the book is devoted to the biomedical aspects of light, including photoimmunology, photoallergic reactions and other forms of light sensitivity, the optical properties of skin, and various ways that light can be used in therapy treatments.Useful to photobiologists as a comprehensive overview, this book should also appeal to biomedical researchers and advanced students of photobiology.

In the 11 years since this atlas first published, the immunology field has experienced an exponential increase in information. Besides the unprecedented advances in knowledge of cell receptors and signal transduction pathways, an avalanche of new information has been gleaned from contemporary research concerning cytokines and chemokines, with speci

Offering broad coverage of the basic, clinical and curative aspects of photomedicine, this reference reflects the recent expansion of knowledge on the effects of light on normal skin as well as photosensitivity disorders and the use of light in treating various diseases and conditions.;The book demonstrates how light acts as a therapeutic agent by means such as phototherapy, photochemotherapy, extracorporeal photopheresis, and the use of lasers in photomedicine and photodynamic therapy.;Providing a detailed introduction to the subject, Clinical Photomedicine: discusses the fundamental principles of photomedicine such as skin optics, light sources, and pharmacology; explicates the acute and chronic effects of light on normal skin, including sunburn reaction, photoaging, and skin cancer; considers photoimmunology; examines clinical photosensitivity diseases as well as topical and systemic photoprotection; and much more.;With over 1300 literature citations, Clinical Photomedicine is designed as a resource for dermatologists and photobiologists, as well as residents and fellows in these disciplines.

A guide to the field of dermatotoxicology. This edition includes fundamental information on the mechanisms of action of toxic substances on skin as well as practical information on the varied responses of skin to specific toxic substances and approaches to evaluating dermal toxicity. Other topics discussed include: hostile natural elements, such as ultraviolet radiation, poisonous plants, man-made detergents and chemicals; problems associated with chronic occupational skin exposure to toxic chemicals; animal alternative research programmes; carcinogenic and Photo Carcinogenic Potential Of Xenobiotic Chemicals; Oculotoxicity; Risk assessment and management; and cosmetic safety. Anatomical factors affecting barrier functions/ lipids of the permeability barrier/the skin immune system.