Bringing together the concerted efforts of the multicomponent materials community in one decisive reference work, this handbook covers all the important aspects from fundamentals to applications: thermodynamics, microscopic processes, solidification, simulation and modeling. As such, it provides a vital understanding of melt and solidification processes, treating all simulation techniques for continuous and discrete systems, such as molecular dynamics, Monte Carlo, and finite elements calculations.

In the decade since the first edition of this popular text was published, the metallurgical field has undergone rapid developments in many sectors. Nonetheless, the underlying principles governing these developments remain the same. A textbook that presents these advances within the context of the fundamentals is greatly needed by instructors in the field Phase Transformations in Metals and Alloys, Second Edition maintains the simplicity that undergraduate instructors and students have come to appreciate while updating and expanding coverage of recently developed methods and materials. The book is effectively divided into two parts. The beginning chapters contain the background material necessary for understanding phase transformations - thermodynamics, kinetics, diffusion theory and the structure and properties of interfaces. The following chapters deal with specific transformations - solidification, diffusional transformation in solids and diffusionless transformation. Case studies of engineering alloys are incorporated to provide a link between theory and practice. New additions include an extended list of further reading at the end of each chapter and a section containing complete solutions to all exercises in the book Designed for final year undergraduate and postgraduate students of metallurgy, materials science, or engineering materials, this is an ideal textbook for both students and instructors.

Expanded and revised to cover developments in the field over the past 17 years, and now reprinted to correct errors in the prior printing, Phase Transformation in Metals and Alloys, Third Edition provides information and examples that better illustrate the engineering relevance of this topic. It supplies a comprehensive overview of specific types o

Current interest in research of solidification of melts is focussed to understand crystal nucleation and crystal growth. They determine the solidified product with its physical properties. A detailed description of these processes lead to the development and validation of physical models, which may form the basis of quantitative modelling of solidification routes in e.g. casting and foundry processes in order to develop a predictive capability in the design of materials during solidification. This book, based on a symposium held at EUROMAT 2003 aims to gives an overview on current developments in the research of solidification and crystallisation of liquids. The materials of interest range from metals and their alloys over semiconductors and isolators to organic substances.

This monograph describes mathematical models that enable prediction of phase compositions for various technological processes, as developed on the base of a complex physico-chemical analysis of reaction. It studies thermodynamics and kinetics of specific stages of complex pyrometallurgical processes involving boron, carbon, sulfur, tungsten, phosphorus, and many more, as well as their exposure to all sorts of factors. First and foremost, this enables to optimize processes and technologies at the stage of design, while traditional empirical means of development of new technologies are basically incapable of providing an optimal solution. Simulation results of metals and alloys production, welding and coating technologies allow obtaining materials with pre-given composition, structure and properties in a cost-saving and conscious manner. Moreover, a so-called "inverse problem", i.e., selecting source materials which would ensure the required results, cannot be solved by any other means.

Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice, Second Edition illustrates how to develop high-quality, safe, and effective pharmaceutical products by discussing the latest techniques, tools, and scientific advances in preformulation investigation, formulation, process design, characterization, scale-up, and production operations. This book covers the essential principles of physical pharmacy, biopharmaceutics, and industrial pharmacy, and their application to the research and development process of oral dosage forms. Chapters have been added, combined, deleted, and completely revised as necessary to produce a comprehensive, well-organized, valuable reference for industry professionals and academics engaged in all aspects of the development process. New and important topics include spray drying, amorphous solid dispersion using hot-melt extrusion, modeling and simulation, bioequivalence of complex modified-released dosage forms, biowaivers, and much more. - Written and edited by an international team of leading experts with experience and knowledge across industry, academia, and regulatory settings - Includes new chapters covering the pharmaceutical applications of surface phenomenon, predictive biopharmaceutics and pharmacokinetics, the development of formulations for drug discovery support, and much more - Presents new case studies throughout, and a section completely devoted to regulatory aspects, including global product regulation and international perspectives