Exploring the functional anatomy and physiology of the ventilatory control system from the intracellular to the integrative level, this references serves as the first source to offer comprehensive coverage of the influences of various pharmacological agents on the control of breathing.

On 15 November 1997, the first international symposium "Neural and Chemical Control of Breathing: Pharmacological and Clinical Aspects" was held at Leiden University Medical Center on the occasion of the retirement of one of the members of the Control of Breathing Research Group of the Departments of Physiology and Anesthesiology, Dr. Aad Berkenbosch. Among others, Dr. Berkenbosch, played an important role in this research group, which made a large and significant contribution to scientific research on the regulation of breathing. This book presents the proceedings of that meeting together with papers of several authors who have strong bonds with the Leiden Departments of Physiology and Anesthesiology. All studies represent state of the art work on the subject of respiratory control and cardiovascular medicine, with emphasis on the physiological, pharmacological and anesthesiological aspects of both fields. The book is divided in several sections: Oxygen Physiology. Prof. John Severinghaus presents among other things his ideas on oxygen sensing and high altitude related diseases. Prof. Honda gives results from studies in a unique set of subjects without carotid bodies. The findings of Honda's group support the idea that an intact hypoxic drive from the carotid bodies is necessary for the generation of central hypoxic depression. Dr. Hans van Beek discusses the effects of hypoxia and hypercapnia on cardiac contractility in animal models. Prof. Oeseburg demonstrates the feasibility of Near Infra Red Oximetry for monitoring tissue oxygenation in patients. Central Chemoreception.

The field of neural control of breathing has advanced rapidly in the past two decades, with the emergence of many new and promising research directions of increasing sophistication. The complexity and diversity of the current methodologies signify its remarkable vivacity, albeit at the price of much confusion. Captured in this book are the broad and intricate nature of the field and its multifaceted frontiers, including aspects of genetics, cell and molecular biology, comparative biology, neurophysiology, neurochemistry, neuroanatomy, imaging, human physiology in health and disease, and influence of environmental factors. Major topics include chemosensitivity, respiratory sensation, respiratory neurons, rhythmogenesis, plasticity, development, chemoreflex and exercise, respiratory instability and variability with behavioral and sleep states, etc., which are systematically laid out in the book for easy referencing.

A quick reference to basic science for anaesthetists, containing all the key information needed for FRCA exams.

This easy yet comprehensive reference guide covers the mechanisms of respiratory diseases, explaining the main respiratory conditions for clinicians and postgraduate trainees. It discusses their aetiology as well as the basic concepts required to effectively evaluate and treat them. Applied Respiratory Pathophysiology is the first book to bring together detailed, clinically-relevant explanation of respiratory physiological processes and pathophysiological processes in one text. It is essential reading for anyone diagnosing and treating specific clinical conditions of the lungs.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Essential for USMLE and certification review! Gain a complete understanding of the aspects of pulmonary physiology essential to clinical medicine For more than thirty-five years, this trusted review has provided students, residents, and fellows with a solid background in the aspects of pulmonary physiology that are essential for an understanding of clinical medicine. The book clearly describes how and why the human respiratory system works in a style that is easy to absorb and integrate with your existing knowledge of other body systems. Features: •Thoroughly updated with new figures, tables, and end-of-chapter references and clinical correlations •Each chapter includes clearly stated learning objectives, summaries of key concepts, illustrations of essential concepts, clinical correlations, problems, and pulmonary function test data to interpret, and suggested readings •Enables you to understand the basic concepts of pulmonary physiology well enough to apply them with confidence in future practice •Provides detailed explanations of physiologic mechanisms and demonstrates how they apply to pathologic states If you’re in need of a concise, time-tested, basic review of pulmonary physiology -- one that encourages comprehension rather than memorization, your search ends here.