Abstract: Medicinal plants have widely been used in the traditional treatment of ailments and have been proven effective. Their contribution still holds an important place in modern drug discovery due to their chemical, and biological diversities. However, the poor documentation of traditional medicine, in developing African countries for instance, can lead to the loss of knowledge related to such practices. In this study, we present the Eastern Africa Natural Products Database (EANPDB) containing the structural and bioactivity information of 1870 unique molecules isolated from about 300 source species from the Eastern African region. This represents the largest collection of natural products (NPs) from this geographical region, covering literature data of the period from 1962 to 2019. The computed physicochemical properties and toxicity profiles of each compound have been included. A comparative analysis of some physico-chemical properties like molecular weight, H-bond donor/acceptor, logPo/w, etc. as well scaffold diversity analysis has been carried out with other published NP databases. EANPDB was combined with the previously published Northern African Natural Products Database (NANPDB), to form a merger African Natural Products Database (ANPDB), containing ∼6500 unique molecules isolated from about 1000 source species (freely available at http://african-compounds.org). As a case study, latrunculins A and B isolated from the sponge Negombata magnifica (Podospongiidae) with previously reported antitumour activities, were identified via substructure searching as molecules to be explored as putative binders of histone deacetylases (HDACs)

Medicinal Plants of East Africa is a revised edition of the book first published in 1976 on herbal remedies and he traditional medical practice of East Africa. The book covers the rich diversity of plants found in Kenya, Tanzania and Uganda, from sea to alpine plants. East Africa also has a rich ethnic diversity and a large number of herbalists whose traditional knowledge and practices are also covered in the book. Over 1500 species are described and for the first time over 200 of these herbs have been illustrated. Also included are maps detailing where the herbs were collected and an ethnographic map detailing the tribes of each herbalist whose knowledge is contained in the book. John Kokwaro is an Eminent Professor of Botany and a research specialist on herbal remedies at the University of Nairobi.

The pharmacopoeias of most African countries are available and contain an impressive number of medicinal plants used for various therapeutic purposes. Many African scholars have distinguished themselves in the fields of organic chemistry, pharmacology, and pharmacognosy and other areas related to the study of plant medicinal plants. However, until now, there is no global standard book on the nature and specificity of chemicals isolated in African medicinal plants, as well as a book bringing together and discussing the main bioactive metabolites of these plants. This book explores the essence of natural substances from African medicinal plants and their pharmacological potential. In light of possible academic use, this book also scans the bulk of African medicinal plants extract having promising pharmacological activities. The book contains data of biologically active plants of Africa, plant occurring compounds and synthesis pathways of secondary metabolites This book explores the essence of natural substances from African medicinal plants and their pharmacological potential The authors are world reknowned African Scientists

Medicinal Plants of East Africa is a fully illustrated guide to 136 East African plants with important medicinal applications. Initially released in 2010, this fully revised edition updates the species descriptions, photographs and range of medicinal uses, and expands on the pharmacological properties of the plant parts.Supported by more than 600 photographs, the book:* describes the characters and ecology of each plant to aid identification* lists indigenous names of species in 92 languages spoken in the region* details the medicinal uses of the different plant parts by drawing on traditional knowledge* includes recipes for the preparation and administration of remedies used to treat common ailments and afflictions* discusses the active chemical compounds found in each plant to explain and unpack the healing properties at workCovering Kenya, Tanzania, and Uganda, this volume is a vital addition to the bookshelves of botanists, health and wellness practitioners, students, travelers, and all who have an interest in the healing properties of plants.

Medicinal Plants of East Africa is the first photographically illustrated guide to showcase the most important healing plants of the region. The book describes 136 plant species in everyday use in Kenya, Tanzania and Uganda. Brief descriptions of each species cover that plant’s appearance, ecology and specific medicinal uses. To aid identification, more than 600 colour photographs have been included. Also included are recipes for remedies to treat a wide range of ailments. An easy-to-understand summary of the science behind the treatments concludes each section. Supplementary features: Introduction to the medicinal virtues and active ingredients of plants; Common methods of preparing medicines from plant materials; Summary of ailments and the plants prescribed to treat them; Glossaries of medical and botanical terminology and extensive reference lists. Medicinal Plants of East Africa will appeal to ethnobotanists, health and wellness practitioners, travellers and all with an interest in the remarkable healing properties of plants. Sales Points: Easy ID with supporting colour photos; recipes for plant remedies; simplifies the science behind the natural medicines; accomplished author team.

The pharmacopoeias of most African countries are available and contain an impressive number of medicinal plants used for various therapeutic purposes. Many African scholars have distinguished themselves in the fields of organic chemistry, pharmacology, and pharmacognosy and other areas related to the study of plant medicinal plants. However, until now, there is no global standard book on the nature and specificity of chemicals isolated in African medicinal plants, as well as a book bringing together and discussing the main bioactive metabolites of these plants. This book explores the essence of natural substances from African medicinal plants and their pharmacological potential. In light of possible academic use, this book also scans the bulk of African medicinal plants extract having promising pharmacological activities. The book contains data of biologically active plants of Africa, plant occurring compounds and synthesis pathways of secondary metabolites.This book explores the essence of natural substances from African medicinal plants and their pharmacological potentialThe authors are world reknowned African Scientists.