Scientific Study from the year 2020 in the subject Veterinary medicine, grade: 500, , language: English, abstract: The monograph summarizes for the first time the data of the literature and own preclinical and clinical studies of iron (IV) clatrochelate. Data on its physicochemical properties, acute and chronic toxicity, features of accumulation of iron in new rare valences in the form of clatrochelate are described. For the first time its antianemic activity is characterized. The scientific publication is intended for a wide range of scientists, teachers, graduate students, students of higher education institutions, veterinary specialists. An animal health is now regarded as one of the factors of the veterinary well-being in every country, so the issue of treating animals with pathological conditions and their prevention is given considerable attention by both scientists and veterinary practitioners. Uncontrolled usage of medicines cause an increase of toxic effects in human and animals organisms. In accordance with the guidelines of the preclinical study of drugs, every new drug must be evaluated for the following indicators: the toxicity of the bioassay to infusoria; the toxicity in laboratory animals after a single administration (acute toxicity); the cumulative properties; the toxicity in laboratory animals after long-term administration (chronic toxicity). The following study works with animal obduction and shows the methodology in pictures.

This essential volume comprehensively discusses redox-active therapeutics, focusing particularly on their molecular design, mechanistic, pharmacological and medicinal aspects. The first section of the book describes the basic aspects of the chemistry and biology of redox-active drugs and includes a brief overview of the redox-based pathways involved in cancer and the medical aspects of redox-active drugs, assuming little in the way of prior knowledge. Subsequent sections and chapters describe more specialized aspects of central nervous system injuries, neurodegenerative diseases, pain, radiation injury and radioprotection (such as of brain, lungs, head and neck and erectile function) and neglected diseases (e.g., leishmaniasis). It encompasses several major classes of redox-active experimental therapeutics, which include porphyrins, salens, nitrones, and most notably metal-containing (e.g., Mn, Fe, Cu, Zn, Sb) drugs as either single compounds or formulations with nanomaterials and quantum dots. Numerous illustrations, tables and figures enhance and complement the text; extensive references to relevant literature are also included. Redox-Active Therapeutics is an invaluable addition to Springer’s Oxidative Stress in Applied Basic Research and Clinical Practice series. It is essential reading for researchers, clinicians and graduate students interested in understanding and exploring the Redoxome—the organism redox network—as an emerging frontier in drug design, redox biology and medicine.

The present volume, "Manganese" D 5, continues the description of the manganese complexes. The arrangement of the complexes in these D volumes is based on the ligand type. The introduction, on p. 1, shows the classes of complexes, which have already been described in Chapters 1 to 21 in the Volumes D 1 (1979), D 2 (1980), D 3 (1982), and D 4 (1985). In Chapters 22 to 29 of this volume are treated complexes with amine-N-polycarboxylic acids, hydrazinecarboxylic acids, amides, hydrazides, derivatives of hydroxylamine (e.g., hydroxamic acids), oximes and nitroso compounds, azo compounds, and triazenes. A survey at the beginning of each of these sections gives information on the most characteristic features of the various complex types. Because of the complexometric relevance of the complexes with amine-N-polycarboxylic acids, there are many studies concerning the existence and the stability of the complexes in solution. Numerous X-ray investigations, reported for the complexes with urea or with amides and hydrazides of carboxylic acids, show the different structures of the compounds as a result of the varying bonding sites of the ligands. Complexes with hydrazides (e.g., with isonicotino hydrazide) are of special interest, due to their biological activity. Complexes with hydroxamic acids, oximes or azo compounds have been studied mostly in aqueous organic or pure organic solvents. The characteristic intense colors of many solutions are used for the analytical determination of manganese.

Jetzt in neuer Auflage: Das erfolgreiche Lehrwerk über Kinetik und Mechanismen anorganischer und organometallischer Reaktionen für fortgeschrittene Studenten! Hervorragend geeignet als Begleiter eines Vorlesungssemesters. Mit zahlreichen Übungsaufgaben; für eine bessere Übersicht sorgen Zusammenfassungen am Ende jedes Kapitels.

Nanomaterials for Electrocatalysis provides an overview of the different types of nanomaterials, design principles and synthesis protocols used for electrocatalytic reactions. The book is divided into four parts that thoroughly describe basic principles and fundamental of electrocatalysis, different types of nanomaterials used, and their electrocatalytic applications, limitations and future perspectives. As electrochemical systems containing nanomaterials, with relevance to experimental situation, yield better results, this book highlights new information and findings. Provides an overview of nanomaterials applications for electrocatalytic processes, such as oxygen reduction reaction (ORR), oxygen evolution reaction (OER), hydrogen evolution reaction (HER) and CO2 reduction reaction (CO2RR) Provides information on the design and development of various nanomaterials appropriate for electrocatalytic applications Assesses the challenges of manufacturing nanomaterials at an industrial scale for electronic applications

A guide to the effective catalysts and latest advances in CO2 conversion in chemicals and fuels Carbon dioxide hydrogenation is one of the most promising and economic techniques to utilize CO2 emissions to produce value-added chemicals. With contributions from an international team of experts on the topic, CO2 Hydrogenation Catalysis offers a comprehensive review of the most recent developments in the catalytic hydrogenation of carbon dioxide to formic acid/formate, methanol, methane, and C2+ products. The book explores the electroreduction of carbon dioxide and contains an overview on hydrogen production from formic acid and methanol. With a practical review of the advances and challenges in future CO2 hydrogenation research, the book provides an important guide for researchers in academia and industry working in the field of catalysis, organometallic chemistry, green and sustainable chemistry, as well as energy conversion and storage. This important book: Offers a unique review of effective catalysts and the latest advances in CO2 conversion Explores how to utilize CO2 emissions to produce value-added chemicals and fuels such as methanol, olefins, gasoline, aromatics Includes the latest research in homogeneous and heterogeneous catalysis as well as electrocatalysis Highlights advances and challenges for future investigation Written for chemists, catalytic chemists, electrochemists, chemists in industry, and chemical engineers, CO2 Hydrogenation Catalysis offers a comprehensive resource to understanding how CO2 emissions can create value-added chemicals.