This book constitutes the refereed proceedings of the Second International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI'99, held in Cambridge, UK, in September 1999. The 133 revised full papers presented were carefully reviewed and selected from a total of 213 full-length papers submitted. The book is divided into topical sections on data-driven segmentation, segmentation using structural models, image processing and feature detection, surfaces and shape, measurement and interpretation, spatiotemporal and diffusion tensor analysis, registration and fusion, visualization, image-guided intervention, robotic systems, and biomechanics and simulation.

Deep brain stimulation has been used effectively for many years to treat patients suffering from Parkinson's disease. Now, neurologists and neurosurgeons are using electric pulse generators to block abnormal activity, i.e. epileptic fits. Promising research results indicate that electric pulses implanted deep in the brain can affect neurocircuitry and help stop oncoming seizures. Supplying a solid background on brain stimulation and its application to epilepsy, Deep Brain Stimulation and Epilepsy provides a historical overview, explores pathogenesis of brain stimulation, discusses animal experiments and human studies, and explores future prospects of brain stimulation for epileptic control. The editor and his team of contributors distill information drawn directly from the literature into one convenient resource.