This book gives a brief overview of the "Patient Blood Management" (PBM) concept and is addressed to health professionals as well as all persons generally involved into hospital management. "Patient Blood Management" (PBM) is a multidisciplinary, evidence-based approach to improve perioperative care. The concept is based on three pillars that target modifiable risk factors for adverse outcome: i) preoperative screening, diagnosis and treatment of anaemia, ii) blood-sparing techniques, and iii) adequate blood product utilization. The superior objective is to optimize patient outcome. Anaemia is common among hospital patients and an underestimated risk factor for blood transfusions, higher morbidity and mortality. Optimizing and preserving red cell mass before, during and after surgery can be achieved by a number of measures that can be implemented in EVERY hospital. These measures have high potential to improve patient outcome and to reduce costs both for allogeneic blood transfusions and for the treatment of the associated complications. Furthermore, due to the current demographical development, the offer of available blood products is most likely to decrease in the future whilst advances in modern medicine increase blood product demands, thus causing scarcity. Therefore, it is our duty towards society, patients and donors to use blood products wisely and only when absolutely necessary. Patient Blood Management is our strategy to face this challenge. The use of a PBM concept will be of benefit for patients, society, doctors and hospitals. This book, written by the key members of the University Hospital Frankfurt PBM project, aims to give a deeper understanding of the three pillars of the concept, and provide insights for undertaking further research as well as planning and implementing concrete operative measures.

Patient Blood Management (PBM) has been increasingly recognized as a fundamental element of good clinical practice in transfusion. The importance of implementing effective PBM had been highlighted in the WHA 63.12 (2010) and reconfirmed in the WHO Action Framework to advance universal access to safe, effective and quality assured blood products 2020-2023 which was launched in February 2020. This policy brief aims: (1) to raise awareness of health authorities and other governmental agencies on the benefits of PBM in improving the population health status, patient outcomes, patients’ safety and quality of care, improving clinical transfusion practice while saving costs; (2) to emphasize governments should take the leadership roles, including allocating sufficient funds to create the structural needs to enable nationwide PBM implementation; and (3) to encourage effective incorporation of PBM into daily clinical practice by creating awareness in patients at large and their health care providers, that anemia and/or moderate to severe blood loss are serious predictors of adverse outcomes. The target audience of this policy brief is government representatives/health authorities, executives of health services and hospitals, health care practitioners, other stakeholder groups including private and public funders/payers, medical schools, professional societies, patient organizations, quality and safety regulatory and accreditation organizations.

Patient Blood Management (PBM) is an innovative clinical concept that aims to reduce the need for allogenic blood transfusions, cut health-care costs, and avert or correct the risk factors related to blood transfusion, thus minimizing the rate of side effects and complications. This comprehensive hands-on volume offers a three-point approach for the implementation of PBM to improve patient outcome, focusing on how to prevent or treat anemia, reduce blood loss, and increase anemia tolerance. The book also goes beyond preoperative PBM, with detailed accounts of coagulation disorder management and the administration of coagulation products and platelet concentrates. Special Features: Presents a clear three-pillar strategy for the application of PBM: diagnosis and treatment of anemia, reduction of peri-interventional blood loss, and optimization of the tolerance to anemia in the everyday clinical setting Covers issues such as PBM during surgery, requirements for modern transfusion medicine, ordering blood products, the role of pre-anesthesia clinics, benchmarking processes, and potential implications of PBM in the public health sector Overview of research in PBM including landmark studies and current clinical trials Boxes in each chapter highlighting key information, core statements, and summaries A multidisciplinary and international team of contributors experienced in PBM Patient Blood Management is a guide for clinicians and residents whose patients are at risk for anemia, coagulation disorders, or severe blood loss. Anesthesiologists, surgeons, and specialists involved in the use of blood and blood products can use the book for quick reference or to learn more about a leading-edge concept for optimizing patient safety and improving outcome.

The Standards for a Patient Blood Management Program (PBM Standards) can help facilities that are implementing or enhancing patient blood management efforts to have a solid foundation for maintaining and optimizing the care of patients who may or may not need transfusion. Like other AABB standards, the requirements in this edition include over-arching quality standards as well as specific technical standards - all firmly grounded in a quality systems framework. Unlike other AABB standards, the requirements in this edition are organized to reflect the wide range of clinical services offered by different hospitals. The PBM Standards acknowledges three distinct PBM program activity levels that reflect the functions an individual facility may perform.

" Preoperative anemia is a pervasive modifiable risk factor often ignored in surgical patients. It is associated with exposure to blood transfusions, increasing morbidity and mortality. Preoperative iron deficiency anemia screening, evaluation, and management as part of a Patient Blood Management (PBM) program increases safety and improves patients' surgical outcomes. From May to July 2021, clinicians at a South Florida hospital were introduced to the critical principles of PBM and learned how to optimize a patient's blood before surgery. The education included practical and tactical components to increase the clinician's knowledge of preoperative anemia risks and management and other blood conservation PBM strategies. Clinicians' PBM knowledge and their intent to change practice were measured before and after a one-hour PBM educational PowerPoint presentation. The quality improvement (QI) initiative demonstrated a knowledge gap. The project achieved two significant outcomes: (1) increased PBM knowledge with a mean score of 90% (paired t-test p-value =

For many physicians and clinicians and across many different specialties, blood transfusion is still considered the first line treatment when facing anaemia and/or blood loss. In the European Union (EU), more than 5 million patients are receiving around 24 million units of blood or blood components each year (Annual Summary of the Reporting of Serious Adverse Reactions and Events, 2015, European Commission). However, a large body of clinical evidence shows that in many clinical scenarios both anaemia and blood loss can be effectively treated with a series of evidence-based measures to better manage and preserve a patient’s own blood, rather than resorting to a donor’s blood, thus leading to a significant overall reduction of blood transfusions. This is why over the last decade the focus in the EU, and elsewhere, has shifted from ensuring safety and quality of blood and blood components (product focused) towards a broader concept that takes a holistic, multi-disciplinary approach to caring for each patient’s haematopoietic system in a manner that aims to ensure the best possible outcome (patient-focused). This widely accepted approach is referred to as Patient Blood Management (PBM).

To reduce transfusion-related morbidity and mortality, it is recommended that an integrated approach to blood management is employed using all available tools to reduce a patient's exposure to donor blood. Meeting the need for a book covering the concepts of blood management as a trend towards multidisciplinary blood management, this new edition is an important resource, providing healthcare professionals with a tool to develop background knowledge in blood management, its organization, methods and tools. Practicing clinicians will be fully prepared to successfully start and run blood management programs.