Parkinson's Disease: Current and Future Therapeutics and Clinical Trials
Title | Parkinson's Disease: Current and Future Therapeutics and Clinical Trials PDF eBook |
Author | Néstor Gálvez-Jiménez |
Publisher | Cambridge University Press |
Pages | 385 |
Release | 2016-03-24 |
Genre | Medical |
ISBN | 1107053862 |
This book emphasizes treatment options for Parkinson's disease, providing the necessary clinical and scientific basis for the foundations of solid therapeutics.
Clinical Trials In Parkinson's Disease
Title | Clinical Trials In Parkinson's Disease PDF eBook |
Author | Santiago Perez-Lloret |
Publisher | Humana |
Pages | 0 |
Release | 2020-08-19 |
Genre | Medical |
ISBN | 9781071609118 |
This volume looks at major clinical trials for motor and non-motor symptoms in Parkinson’s Disease (PD) and covers important aspects, including trial design, sample selection, and outcome selection. Chapters in this book discuss topics such as toxin-based rodent or genetic models of PD; clinical trials for motor symptoms, L-DOPA related motor complications, and gait disorders; clinical trials for mood disorders, troubled sleep, autonomic dysfunction; and clinical trials for disease modifying therapies. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory or research center. Cutting-edge and authoritative, Clinical Trials in Parkinson’s Disease is a valuable resource for clinicians and researchers who want to enhance their interpretation of results from clinical trials and to design their own high-quality trials.
Parkinson’s Disease - Animal Models, Current Therapies and Clinical Trials
Title | Parkinson’s Disease - Animal Models, Current Therapies and Clinical Trials PDF eBook |
Author | Sarat Chandra Yenisetti |
Publisher | BoD – Books on Demand |
Pages | 252 |
Release | 2023-12-20 |
Genre | Medical |
ISBN | 1803564881 |
Despite being described about 200 years ago, the pathophysiology of Parkinson’s disease (PD) is not well understood due to its complex etiology and heterogeneity of symptoms and progression. Animal models provide a great opportunity to follow the progression of neurodegeneration and to screen potent therapeutic molecules, knowledge of which can be critical for different levels of clinical trials. Contemporary health technologies are coming in handy to accelerate the pace of developing novel and refined therapeutic strategies for PD. This book, Parkinson’s Disease - Animal Models, Current Therapies and Clinical Trials, provides a comprehensive overview of PD, presenting information on animal models of PD and contemporary therapeutic strategies, health technologies, clinical trials, and their influence on the quality of life of patients with PD.
An Essay on the Shaking Palsy
Title | An Essay on the Shaking Palsy PDF eBook |
Author | James Parkinson |
Publisher | |
Pages | 86 |
Release | 1817 |
Genre | Parkinson's disease |
ISBN |
Recent Advances in Parkinsons Disease
Title | Recent Advances in Parkinsons Disease PDF eBook |
Author | |
Publisher | Elsevier |
Pages | 369 |
Release | 2010-10-13 |
Genre | Psychology |
ISBN | 0444537511 |
This second volume follows on from Part I by reviewing the variety of animal models of PD current available (from drosophila to rodents to non-human primate species) and their specific contributions to PD research. This is followed by comprehensive coverage of functional neuroimaging studies that explore different pathophysiological questions and evaluate treatment outcome in PD patients. Different areas of experimental therapeutics and outstanding challenges to PD treatment are presented in a concluding group of articles. - Complete overview of hot topics and approaches to current PD research, from molecules, to brain circuits, to clinical and therapeutic applications - Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research - All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Neuroscience Trials of the Future
Title | Neuroscience Trials of the Future PDF eBook |
Author | National Academies of Sciences, Engineering, and Medicine |
Publisher | National Academies Press |
Pages | 111 |
Release | 2016-11-07 |
Genre | Medical |
ISBN | 0309442583 |
On March 3-4, 2016, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop in Washington, DC, bringing together key stakeholders to discuss opportunities for improving the integrity, efficiency, and validity of clinical trials for nervous system disorders. Participants in the workshop represented a range of diverse perspectives, including individuals not normally associated with traditional clinical trials. The purpose of this workshop was to generate discussion about not only what is feasible now, but what may be possible with the implementation of cutting-edge technologies in the future.
Non-Motor Symptoms of Parkinson's Disease
Title | Non-Motor Symptoms of Parkinson's Disease PDF eBook |
Author | K. Ray Chaudhuri |
Publisher | Oxford University Press, USA |
Pages | 517 |
Release | 2014 |
Genre | Medical |
ISBN | 0199684243 |
Patients with Parkinson's disease (PD) are known to suffer from motor symptoms of the disease, but they also experience non-motor symptoms (NMS) that are often present before diagnosis or that inevitably emerge with disease progression. The motor symptoms of Parkinson's disease have been extensively researched, and effective clinical tools for their assessment and treatment have been developed and are readily available. In contrast, researchers have only recently begun to focus on the NMS of Parkinson's Disease, which are poorly recognized and inadequately treated by clinicians. The NMS of PD have a significant impact on patient quality of life and mortality and include neuropsychiatric, sleep-related, autonomic, gastrointestinal, and sensory symptoms. While some NMS can be improved with currently available treatments, others may be more refractory and will require research into novel (non-dopaminergic) drug therapies for the future. Edited by members of the UK Parkinson's Disease Non-Motor Group (PD-NMG) and with contributions from international experts, this new edition summarizes the current understanding of NMS symptoms in Parkinson's disease and points the way towards future research.