Pancreatic Beta Cell in Health and Disease

Pancreatic Beta Cell in Health and Disease
Title Pancreatic Beta Cell in Health and Disease PDF eBook
Author Susumu Seino
Publisher Springer Science & Business Media
Pages 475
Release 2008-04-08
Genre Science
ISBN 4431754520

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The beta cells of the pancreatic islets of Langerhans are the only cells in the body that produce and secrete insulin. This metabolic hormone plays a central role in the maintenance of glucose homeostasis. This book provides a comprehensive review of the beta cell in health and disease. The book’s primary aim is to encourage investigators to become actively involved in diabetes research and the search for new approaches to prevent and treat diabetes.

The Pancreatic Beta Cell

The Pancreatic Beta Cell
Title The Pancreatic Beta Cell PDF eBook
Author
Publisher Academic Press
Pages 517
Release 2014-02-20
Genre Medical
ISBN 0128004401

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First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on the pancreatic beta cell. - Expertise of the contributors - Coverage of a vast array of subjects - In depth current information at the molecular to the clinical levels - Three-dimensional structures in color - Elaborate signaling pathways

Genetics of Diabetes Mellitus

Genetics of Diabetes Mellitus
Title Genetics of Diabetes Mellitus PDF eBook
Author William L. Lowe
Publisher Springer Science & Business Media
Pages 268
Release 2001
Genre Medical
ISBN 9780792372523

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Genetics of Diabetes Mellitus is intended to be a resource for both researchers in the field as well as endocrinologists, diabetologists, and geneticists who seek to learn more about this rapidly changing and important field. The text contains chapters from experts in the area who review aspects of the genetics of both type 1 and 2 diabetes mellitus as well as various syndromic forms of diabetes. The chapters are approachable for those who are not experts in the field of genetics but also comprehensive, so as to serve as an important resource for researchers interested in the genetics of diabetes mellitus. A description of basic concepts of the genetics of complex diseases like type 1 and type 2 diabetes is provided as background. Type 1 diabetes is addressed in chapters exploring genetic determinants that affect the autoimmune process characteristic of type 1 diabetes, the role of the insulin gene in the pathogenesis of type 1 diabetes and additional genes that may impact upon the risk of type 1 diabetes. The impact of genetic determinants on the pathophysiology of type 2 diabetes is covered, as are chapters that address specific genes that are important for the development of type 2 diabetes. Finally, syndromic forms of diabetes, including Maturity Onset Diabetes of the Young and mitochondrial diabetes, and the insight that these disorders provide into more common forms of diabetes are reviewed. Thus, this comprehensive and up-to-date text will serve as an important resource for those actively engaged in research in this area and clinicians treating these patients to provide an up-to-date entrée for those seeking to become more knowledgeable in the area.

Stellate Cells in Health and Disease

Stellate Cells in Health and Disease
Title Stellate Cells in Health and Disease PDF eBook
Author Chandrashekhar Gandhi
Publisher Academic Press
Pages 335
Release 2015-04-10
Genre Science
ISBN 0128005440

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Stellate Cells in Health and Disease is a comprehensive reference providing the most up-to-date knowledge and perspectives on the function of stellate cells affecting the liver and other organs. The text presents comprehensive coverage of their already established role in hepatic fibrosis along with the newer emerging evidence for stellate cell participation in the liver cell (hepatocyte) survival and regeneration, hepatic immunobiology, transplant tolerance, and liver cancer. Chapters describe both animal and human research and the relevance of findings from animal research to human pathophysiology, and also contain sections on future directions which will be of special interest to basic and clinical researchers working on liver fibrosis, hepatic biology, and pathobiology. - Presents coverage of the mechanisms of liver fibrosis with stellate cells as a target for therapy. - Shows stellate cells as a major participant in hepatic immunobiology, including transplantation immunology. - Key illustrations show the phenotypical changes in stellate cells in situ and tissue culture, their interactions with other cell types, signaling pathways and demonstrate the functions and roles of stellate cell in pathological processes.

The Endocrine Pancreas

The Endocrine Pancreas
Title The Endocrine Pancreas PDF eBook
Author Ellis Samols
Publisher Lippincott Williams & Wilkins
Pages 568
Release 1991
Genre Medical
ISBN

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The Genetic Landscape of Diabetes

The Genetic Landscape of Diabetes
Title The Genetic Landscape of Diabetes PDF eBook
Author Laura Dean
Publisher
Pages
Release 2004
Genre
ISBN

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Diabetes Mellitus in Children

Diabetes Mellitus in Children
Title Diabetes Mellitus in Children PDF eBook
Author Mark A. Sperling
Publisher
Pages 0
Release 2005
Genre Children
ISBN 9781416027539

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