Anyone who attempts to read genetics or epidemiology research literature needs to understand the essentials of biostatistics. This book, a revised new edition of the successful Essentials of Biostatistics has been written to provide such an understanding to those who have little or no statistical background and who need to keep abreast of new findings in this fast moving field. Unlike many other elementary books on biostatistics, the main focus of this book is to explain basic concepts needed to understand statistical procedures. This Book: Surveys basic statistical methods used in the genetics and epidemiology literature, including maximum likelihood and least squares. Introduces methods, such as permutation testing and bootstrapping, that are becoming more widely used in both genetic and epidemiological research. Is illustrated throughout with simple examples to clarify the statistical methodology. Explains Bayes’ theorem pictorially. Features exercises, with answers to alternate questions, enabling use as a course text. Written at an elementary mathematical level so that readers with high school mathematics will find the content accessible. Graduate students studying genetic epidemiology, researchers and practitioners from genetics, epidemiology, biology, medical research and statistics will find this an invaluable introduction to statistics.

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Biostatistics and Epidemiology/A Primer for Health Professionals offers practical guidelines and gives a concise framework for research and interpretation in the field. In addition to major sections covering statistics and epidemiology, the book includes a comprehensive exploration of scientific methodology, probability, and the clinical trial. The principles and methods described in this book are basic and apply to all medical subspecialties, psychology and education. The primer will be especially useful to public health officials and students looking for an understandable treatment of the subject.

Basic epidemiology provides an introduction to the core principles and methods of epidemiology, with a special emphasis on public health applications in developing countries. This edition includes chapters on the nature and uses of epidemiology; the epidemiological approach to defining and measuring the occurrence of health-related states in populations; the strengths and limitations of epidemiological study designs; and the role of epidemiology in evaluating the effectiveness and efficiency of health care. The book has a particular emphasis on modifiable environmental factors and encourages the application of epidemiology to the prevention of disease and the promotion of health, including environmental and occupational health.

This book covers the statistical models and methods that are used to understand human genetics, following the historical and recent developments of human genetics. Starting with Mendel’s first experiments to genome-wide association studies, the book describes how genetic information can be incorporated into statistical models to discover disease genes. All commonly used approaches in statistical genetics (e.g. aggregation analysis, segregation, linkage analysis, etc), are used, but the focus of the book is modern approaches to association analysis. Numerous examples illustrate key points throughout the text, both of Mendelian and complex genetic disorders. The intended audience is statisticians, biostatisticians, epidemiologists and quantitatively- oriented geneticists and health scientists wanting to learn about statistical methods for genetic analysis, whether to better analyze genetic data, or to pursue research in methodology. A background in intermediate level statistical methods is required. The authors include few mathematical derivations, and the exercises provide problems for students with a broad range of skill levels. No background in genetics is assumed.

High-YieldTM Biostatistics, Epidemiology, and Public Health, Fourth Edition provides a concise review of the biostatistics concepts that are tested in the USMLE Step 1. Information is presented in an easy-to-follow format, with High-Yield Points that help students focus on the most important USMLE Step 1 facts. The High-YieldTM outline format, with tables, diagrams, photographs, and images to clarify important material, provides a concentrated, efficient review for both course exams and the USMLE.