Osteoporosis affects the bone density and leads to soft and fragile bones. Even a small pressure may to lead to broken bones accompanied by persistent pain and hindered body movement. There may be several causes that may lead to reduced bone strength such as anorexia, hyperthyroidism, alcohol, chemotherapy, menopause, etc. This disease on its own has no symptoms but it increases the risk of bone fracture even in case of a low intensity fall. Diagnostic measures include biomarkers, conventional radiography and dual energy x-ray absorptiometry. In this book, using case studies and examples, constant effort has been made to facilitate the in-depth understanding of the complex concepts of this area of study. The topics included in this book on osteoporosis are of utmost significance and bound to provide incredible insights to readers. The book is appropriate for students, orthopedic doctors and experts seeking detailed information in this area.

This issue of Endocrinology and Metabolism Clinics provides a comprehensive review of osteoporosis written by the world's leading experts. Topics include new mechanistic insights into pathophysiology; bisphosphonates; combination therapy; atypical fractures; non-BP anti resorbers; anabolic therapies; calcium; the impact of Vitamin D on bones; extraskeletal effects of Vitamin D; glucocorticoid osteoporosis; relation to anorexia nervosa, coeliac disease, and diabetes; and male osteoporosis.

In this issue of Endocrinology and Metabolism Clinics, Guest Editor Pauline Camacho brings her considerable expertise to the topic of Osteoporosis. - Provides concise and comprehensive coverage of the issues physicians face every day. - Presents the latest information on a timely, focused topic under the leadership of experienced editors in the field.

In this issue of Endocrinology and Metabolism Clinics, Guest Editor Pauline Camacho brings her considerable expertise to the topic of Osteoporosis. Provides concise and comprehensive coverage of the issues physicians face every day. Presents the latest information on a timely, focused topic under the leadership of experienced editors in the field.

This issue of Endocrinology and Metabolism Clinics provides a comprehensive review of osteoporosis written by the world's leading experts. Topics include new mechanistic insights into pathophysiology; bisphosphonates; combination therapy; atypical fractures; non-BP anti resorbers; anabolic therapies; calcium; the impact of Vitamin D on bones; extraskeletal effects of Vitamin D; glucocorticoid osteoporosis; relation to anorexia nervosa, coeliac disease, and diabetes; and male osteoporosis.

This issue of Endocrinology and Metabolism Clinics, guest edited by Dr. Albert Shieh of UCLA, is devoted to Bone Disorders. Articles in this outstanding issue include: Role of Osteocyte in Bone and Non-Bone Disease; Bone-Fat Interaction; Imaging Beyond DXA; Vitamin D in African-Americans; Pre-Menopausal Osteoporosis; Combined Pharmacologic Therapy in Osteoporosis; Drug-Related Adverse Events in Osteoporosis; Novel Therapies for Osteoporosis; Diabetes and Bone Disease; Bariatric Surgery and Bone Metabolism; Hyperparathyroidism and Bone Microarchitecture; FGF-23 Mediated Bone Disease; and Endothelin-Related Bone Disorder.

In a short decade, osteoporosis has been transformed from an inevitable and irreversible disorder of aging to a disorder for which there is true therapeutic optimism. Remarkable strides have been made in the understanding of the biology, diagnostics, and therapeutics of this disorder. This issue presents a summary of some of the most important developments in the field. The purpose of this issue was to identify those areas in which the most significant advances have been made and present them to you in a way this is not only informative but also clinically relevant.