This book is designed to re-establish the position of the oral cavity and its mucosa at the forefront of defence and maintenance of homeostatic mechanisms that protect against disease not just locally but also systemically. The oral mucosa is a unique collection of tissues that constitutes a highly active environment with its own unique microflora and homeostatic interaction with the innate and adaptive immune responses. As an immune tissue the oral mucosa was somewhat neglected in the past owing to the tendency to assume similarity to the gut mucosa. More recently it has become apparent that the oral mucosa is a complex environment and, like the esophageal mucosa, has more in common with vaginal tissue than with the gut. Furthermore, the ability of the oral mucosa to act as an immune inductive site has made it an attractive area of research in terms of desensitization for allergic reactions and possibly autoimmune responses. In this book, recognized experts in the field provide up-to-date coverage of all aspects of the structure and function of the oral mucosa, reflecting important recent advances in knowledge, including at the molecular level.

This textbook details the latest diagnostic and management options available when treating patients with diseases affecting the oral mucosa. It comprehensively covers the content required to successfully pass dermatology and stomatology board examinations, while being a valuable resource for dentistry trainees. Chapters cover aspects of mucosal immunity and clinical scores along with a range of diseases. Didactic features including learning objectives enable the reader to better extrapolate the key concepts covered in each chapter. Diseases of the Oral Mucosa: Study Guide and Review presents an in depth overview of the latest diagnostic tools and management options available for diseases of the oral mucosa and is an ideal resource for trainee and practising dentists, dermatologists and stomatologists preparing to sit board examinations.

One of the most comprehensive illustrated coverages available, this book is a guide to the diagnosis and management of diseases of the oral mucosa, gingivae, teeth, salivary glands, bones, and joints, and also demonstrates the relation of medical disorders to oral disease, with new expanded material on maxillofacial diseases.

For the third edition, the text has been thoroughly revised to keep pace with new concepts in oral medicine. The structure of the text has been clarified and made more practically useful, with references to etiology, clinical images, differential diagnosis, laboratory diagnostic tests, and therapy guidelines. Also new in the third edition: four new chapters, and more than 240 new, exquisite illustrations of lesions and pathologic conditions affecting the oral cavity.

Translational Systems Medicine and Oral Disease bridges the gap between discovery science and clinical oral medicine, providing opportunities for both the scientific and clinical communities to understand how to apply recent findings in cell biology, genomic profiling, and systems medicine to favorably impact the diagnosis, treatment and management of oral diseases. Fully illustrated chapters from leading international contributors explore clinical applications of genomics, proteomics, metabolomics, microbiomics and epigenetics, as well as analytic methods and functional omics in oral medicine. Disease specific chapters detail systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease, and autoimmune disease, among others. In addition, the book emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology and primary care. - Presents the work of leading international researchers and clinicians who speak on the clinical applications of genomics, proteomics, metabolomics, microbiomics, and epigenetics, as well as analytic methods and functional omics in oral medicine - Provides full-color, richly illustrated chapters that examine systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease and autoimmune diseases - Includes clinical case studies that illustrate examples of oral disease diagnostics and management, highlighting points of key importance for the reader - Emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers, and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology, and primary care

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Human Oral Mucosa: Development, Structure and Function is a new text that reflects the considerable increase in knowledge of oral mucosa that has occurred in recent years. Our understanding of the structure of oral mucosa is now established at a molecular rather than a tissue or cellular level. This in turn has revealed a level of function that was previously not suspected, including a sophisticated barrier to the penetration of exogenous materials, and the synthesis of specific antimicrobial compounds, representing components of the innate immune system. There is also a growing realization of commonality in structure and function between regions of oral mucosa and the mucosae of the esophagus and vagina. The aim of the present volume is to provide a more sophisticated text on human oral mucosa than presently exists in textbooks and to bring together information that is otherwise to be found in separate, specialist volumes into a comprehensive text. It relates structure at the molecular, cellular and tissue level to function and to clinical behavior. The volume is directed to advanced students and researchers in oral biology, as well as those in allied areas of investigation, such as dermatology, gynecology, internal medicine and pathology.