"It is the summer of 1854. Cholera has seized London with unprecedented intensity. A metropolis of more than 2 million people, London is just emerging as one of the first modern cities in the world. But lacking the infrastructure necessary to support its dense population - garbage removal, clean water, sewers - the city has become the perfect breeding ground for a terrifying disease that no one knows how to cure." "As their neighbors begin dying, two men are spurred to action: the Reverend Henry Whitehead, whose faith in a benevolent God is shaken by the seemingly random nature of the victims, and Dr. John Snow, whose ideas about contagion have been dismissed by the scientific community, but who is convinced that he knows how the disease is being transmitted. The Ghost Map chronicles the outbreak's spread and the desperate efforts to put an end to the epidemic - and solve the most pressing medical riddle of the age."--BOOK JACKET.

The product of six years of collaborative research, this fine biography offers new interpretations of a pioneering figure in anesthesiology, epidemiology, medical cartography, and public health. It modifies the conventional rags to riches portrait of John Snow by synthesizing fresh information about his early life from archival research and recent studies. It explores the intellectual roots of his commitments to vegetarianism, temperance, and pure drinking water, first developed when he was a medical apprentice and assistant in the north of England. The authors argue that all of Snow's later contributions are traceable to the medical paradigm he imbibed as a medical student in London and put into practice early in his career as a clinician: that medicine as a science required the incorporation of recent developments in its collateral sciences--chiefly anatomy, chemistry, and physiology--in order to understand the causes of disease. Snow's theoretical breakthroughs in anesthesia were extensions of his experimental research in respiratory physiology and the properties of inhaled gases. Shortly thereafter, his understanding of gas laws led him to reject miasmatic explanations for the spread of cholera, and to develop an alternative theory in consonance with what was then known about chemistry and the physiology of digestion. Using all of Snow's writings, the authors follow him when working in his home laboratory, visiting patients throughout London, attending medical society meetings, and conducting studies during the cholera epidemics of 1849 and 1854. The result is a book that demythologizes some overly heroic views of Snow by providing a fairer measure of his actual contributions. It will have an impact not only on the understanding of the man but also on the history of epidemiology and medical science.

Cholera was the classic epidemic disease of the nineteenth century, as the plague had been for the fourteenth. Its defeat was a reflection not only of progress in medical knowledge but of enduring changes in American social thought. Rosenberg has focused his study on New York City, the most highly developed center of this new society. Carefully documented, full of descriptive detail, yet written with an urgent sense of the drama of the epidemic years, this narrative is as absorbing for general audiences as it is for the medical historian. In a new Afterword, Rosenberg discusses changes in historical method and concerns since the original publication of The Cholera Years. "A major work of interpretation of medical and social thought . . . this volume is also to be commended for its skillful, absorbing presentation of the background and the effects of this dread disease."—I.B. Cohen, New York Times "The Cholera Years is a masterful analysis of the moral and social interest attached to epidemic disease, providing generally applicable insights into how the connections between social change, changes in knowledge and changes in technical practice may be conceived."—Steven Shapin, Times Literary Supplement "In a way that is all too rarely done, Rosenberg has skillfully interwoven medical, social, and intellectual history to show how medicine and society interacted and changed during the 19th century. The history of medicine here takes its rightful place in the tapestry of human history."—John B. Blake, Science

This book features various accounts of a cholera outbreak in West London that killed over 500 people in ten days during the late summer of 1854. What had caused the outbreak? Local authorities of the time were flummoxed about the mode by which the disease had spread. What has become known as “the Broad Street pump episode” is one of the most significant early examples of a team-oriented investigation into the causes of an epidemic—a hallmark of epidemiology and public health today. This collection includes documents from the five separate investigations that were conducted into the possible causes. John Snow and Henry Whitehead made independent investigations; inspectors from the General Board of Health and the Sewer Commission, as well as a parish inquiry committee, also scrutinized the outbreak. This volume traces competing notions of how this disease was transmitted, starting with the first pandemic, which reached England in 1831, and it documents how they developed over time.